NN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile. The product is intended for basal insulin treatment of diabetes mellitus.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Liraglutide | Liraglutide may increase the hypoglycemic activities of NN344. |
| Metreleptin | Metreleptin may increase the hypoglycemic activities of NN344. |
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with NN344. |
| Pioglitazone | The risk or severity of adverse effects can be increased when Pioglitazone is combined with NN344. |
| Pramlintide | Pramlintide may increase the hypoglycemic activities of NN344. |
| Rosiglitazone | The risk or severity of congestive heart failure can be increased when NN344 is combined with Rosiglitazone. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with NN344. |
| Edetic acid | Edetic acid may increase the hypoglycemic activities of NN344. |
| Esmolol | Esmolol may increase the hypoglycemic activities of NN344. |
| Landiolol | Landiolol may increase the hypoglycemic activities of NN344. |
| Moxifloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Moxifloxacin. |
| Grepafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Grepafloxacin. |
| Enoxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Ciprofloxacin. |
| Trovafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Trovafloxacin. |
| Nalidixic acid | The therapeutic efficacy of NN344 can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Ofloxacin. |
| Sparfloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Sparfloxacin. |
| Temafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Temafloxacin. |
| Fleroxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of NN344 can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of NN344 can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of NN344 can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of NN344 can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The risk or severity of hypoglycemia can be increased when Methyclothiazide is combined with NN344. |
| Chlorthalidone | The risk or severity of hypoglycemia can be increased when Chlorthalidone is combined with NN344. |
| Bendroflumethiazide | The risk or severity of hypoglycemia can be increased when Bendroflumethiazide is combined with NN344. |
| Metolazone | The risk or severity of hypoglycemia can be increased when Metolazone is combined with NN344. |
| Benzthiazide | The risk or severity of hypoglycemia can be increased when Benzthiazide is combined with NN344. |
| Hydroflumethiazide | The risk or severity of hypoglycemia can be increased when Hydroflumethiazide is combined with NN344. |
| Indapamide | The risk or severity of hypoglycemia can be increased when Indapamide is combined with NN344. |
| Chlorothiazide | The risk or severity of hypoglycemia can be increased when Chlorothiazide is combined with NN344. |
| Hydrochlorothiazide | The risk or severity of hypoglycemia can be increased when Hydrochlorothiazide is combined with NN344. |
| Trichlormethiazide | The risk or severity of hypoglycemia can be increased when Trichlormethiazide is combined with NN344. |
| Polythiazide | The risk or severity of hypoglycemia can be increased when Polythiazide is combined with NN344. |
| Quinethazone | The risk or severity of hypoglycemia can be increased when Quinethazone is combined with NN344. |
| Cyclopenthiazide | The risk or severity of hypoglycemia can be increased when Cyclopenthiazide is combined with NN344. |
| Epitizide | The therapeutic efficacy of NN344 can be decreased when used in combination with Epitizide. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of NN344. |
| Amoxapine | Amoxapine may decrease the hypoglycemic activities of NN344. |
| Trimipramine | Trimipramine may decrease the hypoglycemic activities of NN344. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of NN344. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of NN344. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of NN344. |
| Dosulepin | Dosulepin may decrease the hypoglycemic activities of NN344. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of NN344. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of NN344. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of NN344. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of NN344. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of NN344. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of NN344. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of NN344. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of NN344. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of NN344. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of NN344. |
| Nortriptyline | Nortriptyline may decrease the hypoglycemic activities of NN344. |
| Desipramine | Desipramine may decrease the hypoglycemic activities of NN344. |
| Dapagliflozin | The risk or severity of hypoglycemia can be increased when NN344 is combined with Dapagliflozin. |
| Canagliflozin | The risk or severity of hypoglycemia can be increased when NN344 is combined with Canagliflozin. |
| Leuprolide | The therapeutic efficacy of NN344 can be decreased when used in combination with Leuprolide. |
| Goserelin | The therapeutic efficacy of NN344 can be decreased when used in combination with Goserelin. |
| Nelfinavir | The therapeutic efficacy of NN344 can be decreased when used in combination with Nelfinavir. |
| Indinavir | The therapeutic efficacy of NN344 can be decreased when used in combination with Indinavir. |
| Ziprasidone | The therapeutic efficacy of NN344 can be decreased when used in combination with Ziprasidone. |
| Etonogestrel | The therapeutic efficacy of NN344 can be decreased when used in combination with Etonogestrel. |
| Desogestrel | The therapeutic efficacy of NN344 can be decreased when used in combination with Desogestrel. |
| Olanzapine | The therapeutic efficacy of NN344 can be decreased when used in combination with Olanzapine. |
| Megestrol acetate | The therapeutic efficacy of NN344 can be decreased when used in combination with Megestrol acetate. |
| Clozapine | The therapeutic efficacy of NN344 can be decreased when used in combination with Clozapine. |
| Levonorgestrel | The therapeutic efficacy of NN344 can be decreased when used in combination with Levonorgestrel. |
| Progesterone | The therapeutic efficacy of NN344 can be decreased when used in combination with Progesterone. |
| Chlorpromazine | The therapeutic efficacy of NN344 can be decreased when used in combination with Chlorpromazine. |
| Haloperidol | The therapeutic efficacy of NN344 can be decreased when used in combination with Haloperidol. |
| Ritonavir | The therapeutic efficacy of NN344 can be decreased when used in combination with Ritonavir. |
| Piperazine | The therapeutic efficacy of NN344 can be decreased when used in combination with Piperazine. |
| Medroxyprogesterone acetate | The therapeutic efficacy of NN344 can be decreased when used in combination with Medroxyprogesterone acetate. |
| Niacin | The therapeutic efficacy of NN344 can be decreased when used in combination with Niacin. |
| Epinephrine | The therapeutic efficacy of NN344 can be decreased when used in combination with Epinephrine. |
| Norethisterone | The therapeutic efficacy of NN344 can be decreased when used in combination with Norethisterone. |
| Risperidone | The therapeutic efficacy of NN344 can be decreased when used in combination with Risperidone. |
| Pentamidine | The risk or severity of hypoglycemia can be increased when Pentamidine is combined with NN344. |