Galiximab

DB04901

biotech investigational

Deskripsi

Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 13 to 24 days
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

411 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Galiximab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Galiximab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Galiximab.
Estrone Estrone may increase the thrombogenic activities of Galiximab.
Estradiol Estradiol may increase the thrombogenic activities of Galiximab.
Dienestrol Dienestrol may increase the thrombogenic activities of Galiximab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Galiximab.
Mestranol Mestranol may increase the thrombogenic activities of Galiximab.
Estriol Estriol may increase the thrombogenic activities of Galiximab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Galiximab.
Quinestrol Quinestrol may increase the thrombogenic activities of Galiximab.
Hexestrol Hexestrol may increase the thrombogenic activities of Galiximab.
Tibolone Tibolone may increase the thrombogenic activities of Galiximab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Galiximab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Galiximab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Galiximab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Galiximab.
Zeranol Zeranol may increase the thrombogenic activities of Galiximab.
Equol Equol may increase the thrombogenic activities of Galiximab.
Promestriene Promestriene may increase the thrombogenic activities of Galiximab.
Methallenestril Methallenestril may increase the thrombogenic activities of Galiximab.
Epimestrol Epimestrol may increase the thrombogenic activities of Galiximab.
Moxestrol Moxestrol may increase the thrombogenic activities of Galiximab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Galiximab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Galiximab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Galiximab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Galiximab.
Biochanin A Biochanin A may increase the thrombogenic activities of Galiximab.
Formononetin Formononetin may increase the thrombogenic activities of Galiximab.
Estetrol Estetrol may increase the thrombogenic activities of Galiximab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Galiximab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Galiximab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Galiximab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Galiximab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Galiximab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Galiximab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Galiximab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Galiximab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Galiximab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Galiximab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Galiximab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Galiximab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Galiximab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Galiximab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Galiximab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Galiximab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Galiximab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Galiximab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Galiximab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Galiximab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Galiximab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Galiximab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Galiximab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Galiximab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Galiximab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Galiximab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Galiximab.
Pexelizumab The risk or severity of adverse effects can be increased when Galiximab is combined with Pexelizumab.
Afelimomab The risk or severity of adverse effects can be increased when Galiximab is combined with Afelimomab.
Epratuzumab The risk or severity of adverse effects can be increased when Galiximab is combined with Epratuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Galiximab is combined with Bectumomab.
Oregovomab The risk or severity of adverse effects can be increased when Galiximab is combined with Oregovomab.
IGN311 The risk or severity of adverse effects can be increased when Galiximab is combined with IGN311.
Adecatumumab The risk or severity of adverse effects can be increased when Galiximab is combined with Adecatumumab.
Labetuzumab The risk or severity of adverse effects can be increased when Galiximab is combined with Labetuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Galiximab is combined with Matuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Galiximab is combined with Fontolizumab.
Bavituximab The risk or severity of adverse effects can be increased when Galiximab is combined with Bavituximab.
CR002 The risk or severity of adverse effects can be increased when Galiximab is combined with CR002.
Rozrolimupab The risk or severity of adverse effects can be increased when Galiximab is combined with Rozrolimupab.
Girentuximab The risk or severity of adverse effects can be increased when Galiximab is combined with Girentuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Galiximab is combined with Obiltoxaximab.
XTL-001 The risk or severity of adverse effects can be increased when Galiximab is combined with XTL-001.
NAV 1800 The risk or severity of adverse effects can be increased when Galiximab is combined with NAV 1800.
Briakinumab The risk or severity of adverse effects can be increased when Galiximab is combined with Briakinumab.
Otelixizumab The risk or severity of adverse effects can be increased when Galiximab is combined with Otelixizumab.
AMG 108 The risk or severity of adverse effects can be increased when Galiximab is combined with AMG 108.
Iratumumab The risk or severity of adverse effects can be increased when Galiximab is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Galiximab is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Galiximab is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Galiximab is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Galiximab is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Galiximab is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Galiximab is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Galiximab is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Galiximab is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Galiximab is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Galiximab is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Galiximab is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Galiximab is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Galiximab is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Galiximab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Galiximab is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Galiximab is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Galiximab is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Galiximab is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Galiximab is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Galiximab is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Galiximab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Galiximab is combined with Canakinumab.

Target Protein

T-lymphocyte activation antigen CD80 CD80

Referensi & Sumber

Artikel (PubMed)
  • PMID: 15994148
    Czuczman MS, Thall A, Witzig TE, Vose JM, Younes A, Emmanouilides C, Miller TP, Moore JO, Leonard JP, Gordon LI, Sweetenham J, Alkuzweny B, Finucane DM, Leigh BR: Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma. J Clin Oncol. 2005 Jul 1;23(19):4390-8.
  • PMID: 17470451
    Leonard JP, Friedberg JW, Younes A, Fisher D, Gordon LI, Moore J, Czuczman M, Miller T, Stiff P, Cheson BD, Forero-Torres A, Chieffo N, McKinney B, Finucane D, Molina A: A phase I/II study of galiximab (an anti-CD80 monoclonal antibody) in combination with rituximab for relapsed or refractory, follicular lymphoma. Ann Oncol. 2007 Jul;18(7):1216-23. Epub 2007 Apr 29.
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