There are no reported instances of deliberate or accidental overdosage in humans. Animal toxicology studies have shown no adverse reactions in single doses up to 20 mg/kg and in repeated doses up to 6 mg/kg/day for 13 weeks, which were the highest doses studied. The highest single dose tested in animals represents 800-times the clinical dose.
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the immune response in the treatment of other diseases.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Darbepoetin alfa | The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Thymalfasin. |
| Erythropoietin | The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Thymalfasin. |
| Peginesatide | The risk or severity of Thrombosis can be increased when Peginesatide is combined with Thymalfasin. |
| Methoxy polyethylene glycol-epoetin beta | The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Thymalfasin. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Lidocaine. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Ropivacaine. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Bupivacaine. |
| Cinchocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Cinchocaine. |
| Dyclonine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Dyclonine. |
| Procaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Procaine. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Prilocaine. |
| Proparacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Proparacaine. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Meloxicam. |
| Oxybuprocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Oxybuprocaine. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Cocaine. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Mepivacaine. |
| Levobupivacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Levobupivacaine. |
| Diphenhydramine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Diphenhydramine. |
| Benzocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Benzocaine. |
| Chloroprocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Chloroprocaine. |
| Phenol | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Phenol. |
| Tetrodotoxin | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Tetrodotoxin. |
| Benzyl alcohol | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Benzyl alcohol. |
| Capsaicin | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Capsaicin. |
| Etidocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Etidocaine. |
| Articaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Tetracaine. |
| Propoxycaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Propoxycaine. |
| Pramocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Pramocaine. |
| Butamben | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Butamben. |
| Butacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Butacaine. |
| Oxetacaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Oxetacaine. |
| Ethyl chloride | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Ethyl chloride. |
| Butanilicaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Butanilicaine. |
| Metabutethamine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Metabutethamine. |
| Quinisocaine | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Quinisocaine. |
| Ambroxol | The risk or severity of methemoglobinemia can be increased when Thymalfasin is combined with Ambroxol. |
| Etrasimod | The risk or severity of immunosuppression can be increased when Thymalfasin is combined with Etrasimod. |