Elacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors. In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline. Development is assumed to have been discontinued.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Afatinib | The serum concentration of Afatinib can be increased when it is combined with Elacridar. |
| Bosutinib | The serum concentration of Bosutinib can be increased when it is combined with Elacridar. |
| Brentuximab vedotin | The serum concentration of Brentuximab vedotin can be increased when it is combined with Elacridar. |
| Colchicine | The serum concentration of Colchicine can be increased when it is combined with Elacridar. |
| Edoxaban | The serum concentration of Edoxaban can be increased when it is combined with Elacridar. |
| Ledipasvir | The serum concentration of Ledipasvir can be increased when it is combined with Elacridar. |
| Naloxegol | The serum concentration of Naloxegol can be increased when it is combined with Elacridar. |
| Pazopanib | The serum concentration of Pazopanib can be increased when it is combined with Elacridar. |
| Prucalopride | The serum concentration of Prucalopride can be increased when it is combined with Elacridar. |
| Ranolazine | The serum concentration of Ranolazine can be increased when it is combined with Elacridar. |
| Silodosin | The excretion of Silodosin can be decreased when combined with Elacridar. |
| Topotecan | The serum concentration of Topotecan can be increased when it is combined with Elacridar. |
| Everolimus | The serum concentration of Everolimus can be increased when it is combined with Elacridar. |
| Rifaximin | The serum concentration of Rifaximin can be increased when it is combined with Elacridar. |
| Vincristine | The excretion of Vincristine can be decreased when combined with Elacridar. |
| Doxorubicin | The serum concentration of Doxorubicin can be increased when it is combined with Elacridar. |
| Betrixaban | The serum concentration of Betrixaban can be increased when it is combined with Elacridar. |
| Folic acid | Elacridar may decrease the excretion rate of Folic acid which could result in a higher serum level. |
| Allopurinol | Elacridar may decrease the excretion rate of Allopurinol which could result in a higher serum level. |
| Raloxifene | Elacridar may decrease the excretion rate of Raloxifene which could result in a higher serum level. |
| Celecoxib | Elacridar may decrease the excretion rate of Celecoxib which could result in a higher serum level. |
| Oxaliplatin | Elacridar may decrease the excretion rate of Oxaliplatin which could result in a higher serum level. |
| Fluorouracil | Elacridar may decrease the excretion rate of Fluorouracil which could result in a higher serum level. |
| Testosterone | Elacridar may decrease the excretion rate of Testosterone which could result in a higher serum level. |
| Clofarabine | Elacridar may decrease the excretion rate of Clofarabine which could result in a higher serum level. |
| Nitrofurantoin | Elacridar may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
| Riluzole | Elacridar may decrease the excretion rate of Riluzole which could result in a higher serum level. |
| Sulfasalazine | Elacridar may decrease the excretion rate of Sulfasalazine which could result in a higher serum level. |
| Glyburide | Elacridar may decrease the excretion rate of Glyburide which could result in a higher serum level. |
| Tegaserod | Elacridar may decrease the excretion rate of Tegaserod which could result in a higher serum level. |
| Leflunomide | Elacridar may decrease the excretion rate of Leflunomide which could result in a higher serum level. |
| Rosuvastatin | Elacridar may decrease the excretion rate of Rosuvastatin which could result in a higher serum level. |
| Alvocidib | Elacridar may decrease the excretion rate of Alvocidib which could result in a higher serum level. |
| Teriflunomide | Elacridar may decrease the excretion rate of Teriflunomide which could result in a higher serum level. |
| Riociguat | Elacridar may decrease the excretion rate of Riociguat which could result in a higher serum level. |
| Palbociclib | Elacridar may decrease the excretion rate of Palbociclib which could result in a higher serum level. |
| Fimasartan | Elacridar may decrease the excretion rate of Fimasartan which could result in a higher serum level. |
| Delafloxacin | Elacridar may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
| Glasdegib | Elacridar may decrease the excretion rate of Glasdegib which could result in a higher serum level. |
| Brigatinib | Elacridar may decrease the excretion rate of Brigatinib which could result in a higher serum level. |
| Enasidenib | Elacridar may decrease the excretion rate of Enasidenib which could result in a higher serum level. |
| Testosterone cypionate | Elacridar may decrease the excretion rate of Testosterone cypionate which could result in a higher serum level. |
| Testosterone enanthate | Elacridar may decrease the excretion rate of Testosterone enanthate which could result in a higher serum level. |
| Darolutamide | Elacridar may decrease the excretion rate of Darolutamide which could result in a higher serum level. |
| Tazemetostat | Elacridar may decrease the excretion rate of Tazemetostat which could result in a higher serum level. |
| Conjugated estrogens | Elacridar may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level. |
| Gefitinib | Elacridar may decrease the excretion rate of Gefitinib which could result in a higher serum level. |
| Cerivastatin | Elacridar may decrease the excretion rate of Cerivastatin which could result in a higher serum level. |
| Teniposide | Elacridar may decrease the excretion rate of Teniposide which could result in a higher serum level. |
| Prazosin | Elacridar may decrease the excretion rate of Prazosin which could result in a higher serum level. |
| Zidovudine | Elacridar may decrease the excretion rate of Zidovudine which could result in a higher serum level. |
| Ritonavir | Elacridar may decrease the excretion rate of Ritonavir which could result in a higher serum level. |
| Methotrexate | Elacridar may decrease the excretion rate of Methotrexate which could result in a higher serum level. |
| Ivermectin | Elacridar may decrease the excretion rate of Ivermectin which could result in a higher serum level. |
| Imatinib | Elacridar may decrease the excretion rate of Imatinib which could result in a higher serum level. |
| Sumatriptan | Elacridar may decrease the excretion rate of Sumatriptan which could result in a higher serum level. |
| Tamoxifen | Elacridar may decrease the excretion rate of Tamoxifen which could result in a higher serum level. |
| Mycophenolate mofetil | Elacridar may decrease the excretion rate of Mycophenolate mofetil which could result in a higher serum level. |
| Daunorubicin | Elacridar may decrease the excretion rate of Daunorubicin which could result in a higher serum level. |
| Lamivudine | Elacridar may decrease the excretion rate of Lamivudine which could result in a higher serum level. |
| Irinotecan | Elacridar may decrease the excretion rate of Irinotecan which could result in a higher serum level. |
| Donepezil | Elacridar may decrease the excretion rate of Donepezil which could result in a higher serum level. |
| Ezetimibe | Elacridar may decrease the excretion rate of Ezetimibe which could result in a higher serum level. |
| Mitoxantrone | Elacridar may decrease the excretion rate of Mitoxantrone which could result in a higher serum level. |
| Camptothecin | Elacridar may decrease the excretion rate of Camptothecin which could result in a higher serum level. |
| Nilotinib | Elacridar may decrease the excretion rate of Nilotinib which could result in a higher serum level. |
| Tenofovir alafenamide | The serum concentration of Tenofovir alafenamide can be increased when it is combined with Elacridar. |
| Revefenacin | Elacridar may decrease the excretion rate of Revefenacin which could result in a higher serum level. |
| Tucatinib | Elacridar may decrease the excretion rate of Tucatinib which could result in a higher serum level. |
| Selumetinib | Elacridar may decrease the excretion rate of Selumetinib which could result in a higher serum level. |
| Pralatrexate | Elacridar may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
| Ripretinib | Elacridar may decrease the excretion rate of Ripretinib which could result in a higher serum level. |
| Fostemsavir | Elacridar may decrease the excretion rate of Fostemsavir which could result in a higher serum level. |
| Ponatinib | Elacridar may decrease the excretion rate of Ponatinib which could result in a higher serum level. |
| Trilaciclib | Elacridar may decrease the excretion rate of Trilaciclib which could result in a higher serum level. |
| Pravastatin | Elacridar may decrease the excretion rate of Pravastatin which could result in a higher serum level. |
| Sildenafil | The serum concentration of Sildenafil can be increased when it is combined with Elacridar. |
| Morphine | The serum concentration of Morphine can be increased when it is combined with Elacridar. |
| Tenofovir disoproxil | The serum concentration of Tenofovir disoproxil can be increased when it is combined with Elacridar. |
| Clobazam | The serum concentration of Clobazam can be increased when it is combined with Elacridar. |
| Quinine | The serum concentration of Quinine can be increased when it is combined with Elacridar. |
| Toremifene | The serum concentration of Toremifene can be increased when it is combined with Elacridar. |
| Bisoprolol | The serum concentration of Bisoprolol can be increased when it is combined with Elacridar. |
| Simvastatin | The serum concentration of Simvastatin can be increased when it is combined with Elacridar. |
| Mannitol | The serum concentration of Mannitol can be increased when it is combined with Elacridar. |
| Loperamide | The excretion of Loperamide can be decreased when combined with Elacridar. |
| Vardenafil | The serum concentration of Vardenafil can be increased when it is combined with Elacridar. |
| Clomifene | The serum concentration of Clomifene can be increased when it is combined with Elacridar. |
| Fexofenadine | The serum concentration of Fexofenadine can be increased when it is combined with Elacridar. |
| Saquinavir | The serum concentration of Saquinavir can be increased when it is combined with Elacridar. |
| Sitagliptin | The serum concentration of Sitagliptin can be increased when it is combined with Elacridar. |
| Posaconazole | The serum concentration of Posaconazole can be increased when it is combined with Elacridar. |
| Paliperidone | The serum concentration of Paliperidone can be increased when it is combined with Elacridar. |
| Belinostat | The serum concentration of Belinostat can be increased when it is combined with Elacridar. |
| Indacaterol | The serum concentration of Indacaterol can be increased when it is combined with Elacridar. |
| Telaprevir | The serum concentration of Telaprevir can be increased when it is combined with Elacridar. |
| Rivaroxaban | Elacridar may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
| Simeprevir | Elacridar may decrease the excretion rate of Simeprevir which could result in a higher serum level. |
| Ambrisentan | The serum concentration of Ambrisentan can be increased when it is combined with Elacridar. |
| Apixaban | Elacridar may decrease the excretion rate of Apixaban which could result in a higher serum level. |