Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with congestive heart failure. Trials were halted in the U.S., but the drug is used in various countries.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Milrinone | The risk or severity of congestive heart failure, bleeding, hypotension, and Tachycardia can be increased when Milrinone is combined with Enoximone. |
| Anagrelide | The risk or severity of congestive heart failure, bleeding, hypotension, and Tachycardia can be increased when Anagrelide is combined with Enoximone. |
| Cilostazol | The risk or severity of congestive heart failure, bleeding, hypotension, and Tachycardia can be increased when Cilostazol is combined with Enoximone. |
| Amrinone | The risk or severity of congestive heart failure, bleeding, hypotension, and Tachycardia can be increased when Amrinone is combined with Enoximone. |
| Riociguat | Enoximone may increase the hypotensive activities of Riociguat. |
| Patent Blue | The therapeutic efficacy of Enoximone can be decreased when used in combination with Patent Blue. |
| Isosorbide mononitrate | Enoximone may increase the vasodilatory activities of Isosorbide mononitrate. |
| Iloprost | Iloprost may increase the hypotensive activities of Enoximone. |