An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Debrisoquine. |
| Amifostine | Debrisoquine may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Debrisoquine. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Debrisoquine. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Debrisoquine. |
| Obinutuzumab | Debrisoquine may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Debrisoquine. |
| Rituximab | Debrisoquine may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Debrisoquine. |
| Phentermine | Phentermine may decrease the antihypertensive activities of Debrisoquine. |
| Isoetharine | Isoetharine may decrease the antihypertensive activities of Debrisoquine. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Debrisoquine. |
| Etomidate | Etomidate may decrease the antihypertensive activities of Debrisoquine. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Debrisoquine. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Debrisoquine. |
| Norepinephrine | Norepinephrine may decrease the antihypertensive activities of Debrisoquine. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Debrisoquine. |
| Phenylpropanolamine | Phenylpropanolamine may decrease the antihypertensive activities of Debrisoquine. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Debrisoquine. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Debrisoquine. |
| Atropine | Atropine may decrease the antihypertensive activities of Debrisoquine. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Debrisoquine. |
| Epinephrine | Epinephrine may decrease the antihypertensive activities of Debrisoquine. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Debrisoquine. |
| Propiomazine | Propiomazine may decrease the antihypertensive activities of Debrisoquine. |
| Orciprenaline | Orciprenaline may decrease the antihypertensive activities of Debrisoquine. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Debrisoquine. |
| Dobutamine | Dobutamine may decrease the antihypertensive activities of Debrisoquine. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Debrisoquine. |
| Benzphetamine | Benzphetamine may decrease the antihypertensive activities of Debrisoquine. |
| Ritodrine | Ritodrine may decrease the antihypertensive activities of Debrisoquine. |
| Terbutaline | Terbutaline may decrease the antihypertensive activities of Debrisoquine. |
| Bitolterol | Bitolterol may decrease the antihypertensive activities of Debrisoquine. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Debrisoquine. |
| Salmeterol | Salmeterol may decrease the antihypertensive activities of Debrisoquine. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Debrisoquine. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Debrisoquine. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Debrisoquine. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Debrisoquine. |
| Albuterol | Salbutamol may decrease the antihypertensive activities of Debrisoquine. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Debrisoquine. |
| Isoprenaline | Isoprenaline may decrease the antihypertensive activities of Debrisoquine. |
| Arbutamine | Arbutamine may decrease the antihypertensive activities of Debrisoquine. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Debrisoquine. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Debrisoquine. |
| Fenoterol | Fenoterol may decrease the antihypertensive activities of Debrisoquine. |
| Pirbuterol | Pirbuterol may decrease the antihypertensive activities of Debrisoquine. |
| Ephedra sinica root | Ephedra sinica root may decrease the antihypertensive activities of Debrisoquine. |
| Ephedrine | Ephedrine may decrease the antihypertensive activities of Debrisoquine. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Debrisoquine. |
| Procaterol | Procaterol may decrease the antihypertensive activities of Debrisoquine. |
| Clenbuterol | Clenbuterol may decrease the antihypertensive activities of Debrisoquine. |
| Bambuterol | Bambuterol may decrease the antihypertensive activities of Debrisoquine. |
| MMDA | MMDA may decrease the antihypertensive activities of Debrisoquine. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Debrisoquine. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Debrisoquine. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Debrisoquine. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Debrisoquine. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Debrisoquine. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Debrisoquine. |
| Solifenacin | Solifenacin may decrease the antihypertensive activities of Debrisoquine. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Debrisoquine. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Debrisoquine. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Debrisoquine. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Debrisoquine. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Debrisoquine. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Debrisoquine. |
| Amibegron | Amibegron may decrease the antihypertensive activities of Debrisoquine. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Debrisoquine. |
| Nylidrin | Nylidrin may decrease the antihypertensive activities of Debrisoquine. |
| Pizotifen | Pizotifen may decrease the antihypertensive activities of Debrisoquine. |
| Solabegron | Solabegron may decrease the antihypertensive activities of Debrisoquine. |
| Droxidopa | Droxidopa may decrease the antihypertensive activities of Debrisoquine. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Debrisoquine. |
| Xylometazoline | Xylometazoline may decrease the antihypertensive activities of Debrisoquine. |
| Isometheptene | Isometheptene may decrease the antihypertensive activities of Debrisoquine. |
| Levonordefrin | Levonordefrin may decrease the antihypertensive activities of Debrisoquine. |
| Naphazoline | Naphazoline may decrease the antihypertensive activities of Debrisoquine. |
| Saralasin | Saralasin may decrease the antihypertensive activities of Debrisoquine. |
| Tetryzoline | Tetryzoline may decrease the antihypertensive activities of Debrisoquine. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Debrisoquine. |
| Lurasidone | Lurasidone may decrease the antihypertensive activities of Debrisoquine. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Debrisoquine. |
| Adrafinil | Adrafinil may decrease the antihypertensive activities of Debrisoquine. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Debrisoquine. |
| Hexoprenaline | Hexoprenaline may decrease the antihypertensive activities of Debrisoquine. |
| Etilefrine | Etilefrine may decrease the antihypertensive activities of Debrisoquine. |
| Dimetacrine | Dimetacrine may decrease the antihypertensive activities of Debrisoquine. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Debrisoquine. |
| Olodaterol | Olodaterol may decrease the antihypertensive activities of Debrisoquine. |
| Vilanterol | Vilanterol may decrease the antihypertensive activities of Debrisoquine. |
| Cirazoline | Cirazoline may decrease the antihypertensive activities of Debrisoquine. |
| Synephrine | Synephrine may decrease the antihypertensive activities of Debrisoquine. |
| Moxisylyte | Moxisylyte may decrease the antihypertensive activities of Debrisoquine. |
| Tianeptine | Tianeptine may decrease the antihypertensive activities of Debrisoquine. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Debrisoquine. |
| Iofetamine I-123 | Iofetamine I-123 may decrease the antihypertensive activities of Debrisoquine. |
| Racepinephrine | Racepinephrine may decrease the antihypertensive activities of Debrisoquine. |
| Dihydroergocornine | Dihydroergocornine may decrease the antihypertensive activities of Debrisoquine. |
| DL-Methylephedrine | DL-Methylephedrine may decrease the antihypertensive activities of Debrisoquine. |