Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Efavirenz | The serum concentration of Maraviroc can be decreased when it is combined with Efavirenz. |
| Pitolisant | The serum concentration of Maraviroc can be decreased when it is combined with Pitolisant. |
| Metreleptin | The metabolism of Maraviroc can be increased when combined with Metreleptin. |
| Rubella virus vaccine | The therapeutic efficacy of Rubella virus vaccine can be decreased when used in combination with Maraviroc. |
| Bacillus calmette-guerin substrain tice live antigen | The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Maraviroc. |
| Bacillus calmette-guerin substrain connaught live antigen | The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Maraviroc. |
| Yellow fever vaccine | The therapeutic efficacy of Yellow fever vaccine can be decreased when used in combination with Maraviroc. |
| Anthrax vaccine | The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Maraviroc. |
| Typhoid Vaccine Live | The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Maraviroc. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Maraviroc. |
| Human adenovirus e serotype 4 strain cl-68578 antigen | The therapeutic efficacy of Human adenovirus e serotype 4 strain cl-68578 antigen can be decreased when used in combination with Maraviroc. |
| Vibrio cholerae CVD 103-HgR strain live antigen | The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Maraviroc. |
| Adenovirus type 7 vaccine live | The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Maraviroc. |
| Varicella zoster vaccine (live/attenuated) | The therapeutic efficacy of Varicella zoster vaccine (live/attenuated) can be decreased when used in combination with Maraviroc. |
| Bacillus calmette-guerin substrain russian BCG-I live antigen | The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Maraviroc. |
| Pexidartinib | Maraviroc may increase the hepatotoxic activities of Pexidartinib. |
| Cenobamate | The serum concentration of Maraviroc can be decreased when it is combined with Cenobamate. |
| Darunavir | The serum concentration of Maraviroc can be increased when it is combined with Darunavir. |
| Haloperidol | The serum concentration of Haloperidol can be increased when it is combined with Maraviroc. |
| Tucatinib | The metabolism of Tucatinib can be decreased when combined with Maraviroc. |
| Abametapir | The serum concentration of Maraviroc can be increased when it is combined with Abametapir. |
| Satralizumab | The serum concentration of Maraviroc can be decreased when it is combined with Satralizumab. |
| Sotorasib | The serum concentration of Maraviroc can be decreased when it is combined with Sotorasib. |
| Ritonavir | The metabolism of Maraviroc can be decreased when combined with Ritonavir. |
| Boceprevir | The metabolism of Maraviroc can be decreased when combined with Boceprevir. |
| Voriconazole | The metabolism of Maraviroc can be decreased when combined with Voriconazole. |
| Ditiocarb | The metabolism of Maraviroc can be decreased when combined with Ditiocarb. |
| Stiripentol | The metabolism of Maraviroc can be decreased when combined with Stiripentol. |
| Danoprevir | The metabolism of Maraviroc can be decreased when combined with Danoprevir. |
| Methimazole | The metabolism of Maraviroc can be decreased when combined with Methimazole. |
| Terfenadine | The metabolism of Maraviroc can be decreased when combined with Terfenadine. |
| Ergotamine | The metabolism of Maraviroc can be decreased when combined with Ergotamine. |
| Delavirdine | The metabolism of Maraviroc can be decreased when combined with Delavirdine. |
| Conivaptan | The metabolism of Maraviroc can be decreased when combined with Conivaptan. |
| Telithromycin | The metabolism of Maraviroc can be decreased when combined with Telithromycin. |
| Ketoconazole | The metabolism of Maraviroc can be decreased when combined with Ketoconazole. |
| Atazanavir | The metabolism of Maraviroc can be decreased when combined with Atazanavir. |
| Nefazodone | The metabolism of Maraviroc can be decreased when combined with Nefazodone. |
| Itraconazole | The metabolism of Maraviroc can be decreased when combined with Itraconazole. |
| Clarithromycin | The metabolism of Maraviroc can be decreased when combined with Clarithromycin. |
| Saquinavir | The metabolism of Maraviroc can be decreased when combined with Saquinavir. |
| Posaconazole | The metabolism of Maraviroc can be decreased when combined with Posaconazole. |
| Lopinavir | The metabolism of Maraviroc can be decreased when combined with Lopinavir. |
| Nilotinib | The metabolism of Maraviroc can be decreased when combined with Nilotinib. |
| Telaprevir | The metabolism of Maraviroc can be decreased when combined with Telaprevir. |
| Midostaurin | The metabolism of Maraviroc can be decreased when combined with Midostaurin. |
| Elvitegravir | The metabolism of Maraviroc can be decreased when combined with Elvitegravir. |
| Ribociclib | The metabolism of Maraviroc can be decreased when combined with Ribociclib. |
| Troleandomycin | The metabolism of Maraviroc can be decreased when combined with Troleandomycin. |
| Lonafarnib | The metabolism of Maraviroc can be decreased when combined with Lonafarnib. |
| Danazol | The metabolism of Maraviroc can be decreased when combined with Danazol. |
| Nelfinavir | The metabolism of Maraviroc can be decreased when combined with Nelfinavir. |
| Indinavir | The metabolism of Maraviroc can be decreased when combined with Indinavir. |
| Amprenavir | The metabolism of Maraviroc can be decreased when combined with Amprenavir. |
| Amiodarone | The metabolism of Maraviroc can be decreased when combined with Amiodarone. |
| Cyclosporine | The metabolism of Maraviroc can be decreased when combined with Cyclosporine. |
| Fluvoxamine | The metabolism of Maraviroc can be decreased when combined with Fluvoxamine. |
| Fluconazole | The metabolism of Maraviroc can be decreased when combined with Fluconazole. |
| Erythromycin | The serum concentration of Maraviroc can be increased when it is combined with Erythromycin. |
| Ziprasidone | The metabolism of Maraviroc can be decreased when combined with Ziprasidone. |
| Isradipine | The metabolism of Maraviroc can be decreased when combined with Isradipine. |
| Diltiazem | The metabolism of Maraviroc can be decreased when combined with Diltiazem. |
| Clozapine | The metabolism of Maraviroc can be decreased when combined with Clozapine. |
| Ciprofloxacin | The metabolism of Maraviroc can be decreased when combined with Ciprofloxacin. |
| Nicardipine | The metabolism of Maraviroc can be decreased when combined with Nicardipine. |
| Verapamil | The metabolism of Maraviroc can be decreased when combined with Verapamil. |
| Aprepitant | The metabolism of Maraviroc can be decreased when combined with Aprepitant. |
| Isoniazid | The metabolism of Maraviroc can be decreased when combined with Isoniazid. |
| Primaquine | The metabolism of Maraviroc can be decreased when combined with Primaquine. |
| Miconazole | The metabolism of Maraviroc can be decreased when combined with Miconazole. |
| Fusidic acid | The metabolism of Maraviroc can be decreased when combined with Fusidic acid. |
| Zimelidine | The metabolism of Maraviroc can be decreased when combined with Zimelidine. |
| Dronedarone | The metabolism of Maraviroc can be decreased when combined with Dronedarone. |
| Milnacipran | The metabolism of Maraviroc can be decreased when combined with Milnacipran. |
| Simeprevir | The metabolism of Maraviroc can be decreased when combined with Simeprevir. |
| Isavuconazonium | The metabolism of Maraviroc can be decreased when combined with Isavuconazonium. |
| Desvenlafaxine | The metabolism of Maraviroc can be decreased when combined with Desvenlafaxine. |
| Nilvadipine | The metabolism of Maraviroc can be decreased when combined with Nilvadipine. |
| Seproxetine | The metabolism of Maraviroc can be decreased when combined with Seproxetine. |
| Linagliptin | The metabolism of Maraviroc can be decreased when combined with Linagliptin. |
| Indalpine | The metabolism of Maraviroc can be decreased when combined with Indalpine. |
| Netupitant | The metabolism of Maraviroc can be decreased when combined with Netupitant. |
| Barnidipine | The metabolism of Maraviroc can be decreased when combined with Barnidipine. |
| Benidipine | The metabolism of Maraviroc can be decreased when combined with Benidipine. |
| Venetoclax | The metabolism of Maraviroc can be decreased when combined with Venetoclax. |
| Isavuconazole | The metabolism of Maraviroc can be decreased when combined with Isavuconazole. |
| Fosnetupitant | The metabolism of Maraviroc can be decreased when combined with Fosnetupitant. |
| Berotralstat | The metabolism of Maraviroc can be decreased when combined with Berotralstat. |
| Tipranavir | The metabolism of Maraviroc can be decreased when combined with Tipranavir. |
| Phenytoin | The metabolism of Maraviroc can be increased when combined with Phenytoin. |
| Pentobarbital | The metabolism of Maraviroc can be increased when combined with Pentobarbital. |
| Carbamazepine | The metabolism of Maraviroc can be increased when combined with Carbamazepine. |
| Mitotane | The metabolism of Maraviroc can be increased when combined with Mitotane. |
| Primidone | The metabolism of Maraviroc can be increased when combined with Primidone. |
| Rifampin | The metabolism of Maraviroc can be increased when combined with Rifampicin. |
| Phenobarbital | The metabolism of Maraviroc can be increased when combined with Phenobarbital. |
| Dexamethasone | The metabolism of Maraviroc can be increased when combined with Dexamethasone. |
| Fosphenytoin | The metabolism of Maraviroc can be increased when combined with Fosphenytoin. |
| St. John's Wort | The metabolism of Maraviroc can be increased when combined with St. John's Wort. |
| Enzalutamide | The metabolism of Maraviroc can be increased when combined with Enzalutamide. |