Peringatan Keamanan

Estimates for the lethal dosage (LD50) of LSD range from 200 µg/kg to more than 1 mg/kg of human body mass, though most sources report that there are no known human cases of such an overdose.

Lysergic acid diethylamide

DB04829

small molecule illicit investigational withdrawn

Deskripsi

Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and varies according to the susceptibility of the individual to the disorder. Many emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience. However, not all published case reports of chronic flashbacks appear to describe an anxious hyper-vigilant state reminiscent of post-traumatic stress disorder.

Struktur Molekul 2D

Berat 323.432
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 3 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1348 Data
Valsartan Lysergic acid diethylamide may decrease the antihypertensive activities of Valsartan.
Ramipril Lysergic acid diethylamide may decrease the antihypertensive activities of Ramipril.
Remikiren Lysergic acid diethylamide may decrease the antihypertensive activities of Remikiren.
Torasemide Lysergic acid diethylamide may decrease the antihypertensive activities of Torasemide.
Guanadrel Lysergic acid diethylamide may decrease the antihypertensive activities of Guanadrel.
Olmesartan Lysergic acid diethylamide may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Lysergic acid diethylamide may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Lysergic acid diethylamide may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Lysergic acid diethylamide may decrease the antihypertensive activities of Minoxidil.
Treprostinil Lysergic acid diethylamide may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Bendroflumethiazide.
Prazosin Lysergic acid diethylamide may decrease the antihypertensive activities of Prazosin.
Fosinopril Lysergic acid diethylamide may decrease the antihypertensive activities of Fosinopril.
Trandolapril Lysergic acid diethylamide may decrease the antihypertensive activities of Trandolapril.
Metolazone Lysergic acid diethylamide may decrease the antihypertensive activities of Metolazone.
Benazepril Lysergic acid diethylamide may decrease the antihypertensive activities of Benazepril.
Cyclothiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Lysergic acid diethylamide may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Lysergic acid diethylamide may decrease the antihypertensive activities of Mecamylamine.
Moexipril Lysergic acid diethylamide may decrease the antihypertensive activities of Moexipril.
Lisinopril Lysergic acid diethylamide may decrease the antihypertensive activities of Lisinopril.
Hydroflumethiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Lysergic acid diethylamide may decrease the antihypertensive activities of Cryptenamine.
Perindopril Lysergic acid diethylamide may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Lysergic acid diethylamide may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Lysergic acid diethylamide may decrease the antihypertensive activities of Fenoldopam.
Eprosartan Lysergic acid diethylamide may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Lysergic acid diethylamide may decrease the antihypertensive activities of Quinapril.
Telmisartan Lysergic acid diethylamide may decrease the antihypertensive activities of Telmisartan.
Hydrochlorothiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Trichlormethiazide.
Deserpidine Lysergic acid diethylamide may decrease the antihypertensive activities of Deserpidine.
Pentolinium Lysergic acid diethylamide may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Lysergic acid diethylamide may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Lysergic acid diethylamide may decrease the antihypertensive activities of Diazoxide.
Bretylium Lysergic acid diethylamide may decrease the antihypertensive activities of Bretylium.
Terazosin Lysergic acid diethylamide may decrease the antihypertensive activities of Terazosin.
Epoprostenol Lysergic acid diethylamide may decrease the antihypertensive activities of Epoprostenol.
Polythiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Polythiazide.
Cilazapril Lysergic acid diethylamide may decrease the antihypertensive activities of Cilazapril.
Saprisartan Lysergic acid diethylamide may decrease the antihypertensive activities of Saprisartan.
Spirapril Lysergic acid diethylamide may decrease the antihypertensive activities of Spirapril.
Tienilic acid Lysergic acid diethylamide may decrease the antihypertensive activities of Tienilic acid.
Diethylnorspermine Lysergic acid diethylamide may decrease the antihypertensive activities of Diethylnorspermine.
Temocapril Lysergic acid diethylamide may decrease the antihypertensive activities of Temocapril.
Trimazosin Lysergic acid diethylamide may decrease the antihypertensive activities of Trimazosin.
Nicorandil Lysergic acid diethylamide may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Lysergic acid diethylamide may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Enalaprilat.
Angiotensin 1-7 Lysergic acid diethylamide may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Lysergic acid diethylamide may decrease the antihypertensive activities of Imidapril.
BQ-123 Lysergic acid diethylamide may decrease the antihypertensive activities of BQ-123.
Cicletanine Lysergic acid diethylamide may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Lysergic acid diethylamide may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Lysergic acid diethylamide may decrease the antihypertensive activities of Zofenopril.
Guanoxan Lysergic acid diethylamide may decrease the antihypertensive activities of Guanoxan.
Delapril Lysergic acid diethylamide may decrease the antihypertensive activities of Delapril.
Vincamine Lysergic acid diethylamide may decrease the antihypertensive activities of Vincamine.
Linsidomine Lysergic acid diethylamide may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Lysergic acid diethylamide may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Lysergic acid diethylamide may decrease the antihypertensive activities of Tolonidine.
Endralazine Lysergic acid diethylamide may decrease the antihypertensive activities of Endralazine.
Cadralazine Lysergic acid diethylamide may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Lysergic acid diethylamide may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Lysergic acid diethylamide may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Lysergic acid diethylamide may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Lysergic acid diethylamide may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Lysergic acid diethylamide may decrease the antihypertensive activities of Guanoclor.
Muzolimine Lysergic acid diethylamide may decrease the antihypertensive activities of Muzolimine.
Xipamide Lysergic acid diethylamide may decrease the antihypertensive activities of Xipamide.
Candesartan Lysergic acid diethylamide may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Lysergic acid diethylamide may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Lysergic acid diethylamide may decrease the antihypertensive activities of Quinaprilat.
Furosemide Lysergic acid diethylamide may decrease the antihypertensive activities of Furosemide.
Enalapril Lysergic acid diethylamide may decrease the antihypertensive activities of Enalapril.
Captopril Lysergic acid diethylamide may decrease the antihypertensive activities of Captopril.
Amlodipine Lysergic acid diethylamide may decrease the antihypertensive activities of Amlodipine.
Nimodipine Lysergic acid diethylamide may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Lysergic acid diethylamide may decrease the antihypertensive activities of Nisoldipine.
Bosentan Lysergic acid diethylamide may decrease the antihypertensive activities of Bosentan.
Doxazosin Lysergic acid diethylamide may decrease the antihypertensive activities of Doxazosin.
Losartan Lysergic acid diethylamide may decrease the antihypertensive activities of Losartan.
Eplerenone Lysergic acid diethylamide may decrease the antihypertensive activities of Eplerenone.
Indapamide Lysergic acid diethylamide may decrease the antihypertensive activities of Indapamide.
Tadalafil Lysergic acid diethylamide may decrease the antihypertensive activities of Tadalafil.
Irbesartan Lysergic acid diethylamide may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Lysergic acid diethylamide may decrease the antihypertensive activities of Nitrendipine.
Guanethidine Lysergic acid diethylamide may decrease the antihypertensive activities of Guanethidine.
Hydralazine Lysergic acid diethylamide may decrease the antihypertensive activities of Hydralazine.
Sitaxentan Lysergic acid diethylamide may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Lysergic acid diethylamide may decrease the antihypertensive activities of Ambrisentan.
Pinacidil Lysergic acid diethylamide may decrease the antihypertensive activities of Pinacidil.
Riociguat Lysergic acid diethylamide may decrease the antihypertensive activities of Riociguat.
Macitentan Lysergic acid diethylamide may decrease the antihypertensive activities of Macitentan.
Aliskiren Lysergic acid diethylamide may decrease the antihypertensive activities of Aliskiren.

Target Protein

5-hydroxytryptamine receptor 2A HTR2A
5-hydroxytryptamine receptor 1A HTR1A
5-hydroxytryptamine receptor 2B HTR2B
5-hydroxytryptamine receptor 6 HTR6

Referensi & Sumber

Artikel (PubMed)
  • PMID: 13497365
    GREINER T, BURCH NR, EDELBERG R: Psychopathology and psychophysiology of minimal LSD-25 dosage; a preliminary dosage-response spectrum. AMA Arch Neurol Psychiatry. 1958 Feb;79(2):208-10.
  • PMID: 14209776
    AGHAJANIAN GK, BING OH: PERSISTENCE OF LYSERGIC ACID DIETHYLAMIDE IN THE PLASMA OF HUMAN SUBJECTS. Clin Pharmacol Ther. 1964 Sep-Oct;5:611-4.
  • PMID: 2374410
    Papac DI, Foltz RL: Measurement of lysergic acid diethylamide (LSD) in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry. J Anal Toxicol. 1990 May-Jun;14(3):189-90.
  • PMID: 14761703
    Nichols DE: Hallucinogens. Pharmacol Ther. 2004 Feb;101(2):131-81.
  • PMID: 6873185
    Jacobs BL, Heym J, Rasmussen K: Raphe neurons: firing rate correlates with size of drug response. Eur J Pharmacol. 1983 Jun 3;90(2-3):275-8.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Delysid — Sandoz Laboratories

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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