Zomepirac

DB04828

small molecule withdrawn

Deskripsi

Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.

Struktur Molekul 2D

Berat 291.73
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1453 Data
Amlodipine Zomepirac may decrease the antihypertensive activities of Amlodipine.
Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Zomepirac.
Isoetharine The risk or severity of hypertension can be increased when Isoetharine is combined with Zomepirac.
Zolmitriptan The risk or severity of hypertension can be increased when Zolmitriptan is combined with Zomepirac.
Norepinephrine The risk or severity of hypertension can be increased when Norepinephrine is combined with Zomepirac.
Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Zomepirac.
Phenylpropanolamine The risk or severity of hypertension can be increased when Phenylpropanolamine is combined with Zomepirac.
Droperidol The risk or severity of hypertension can be increased when Droperidol is combined with Zomepirac.
Doxapram The risk or severity of hypertension can be increased when Doxapram is combined with Zomepirac.
Atropine The risk or severity of hypertension can be increased when Atropine is combined with Zomepirac.
Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Zomepirac.
Metaraminol The risk or severity of hypertension can be increased when Metaraminol is combined with Zomepirac.
Furazolidone The risk or severity of hypertension can be increased when Furazolidone is combined with Zomepirac.
Thioridazine The risk or severity of hypertension can be increased when Thioridazine is combined with Zomepirac.
Nicergoline The risk or severity of hypertension can be increased when Nicergoline is combined with Zomepirac.
Methoxamine The risk or severity of hypertension can be increased when Methoxamine is combined with Zomepirac.
Isoflurane The risk or severity of hypertension can be increased when Isoflurane is combined with Zomepirac.
Propiomazine The risk or severity of hypertension can be increased when Propiomazine is combined with Zomepirac.
Minaprine The risk or severity of hypertension can be increased when Minaprine is combined with Zomepirac.
Orciprenaline The risk or severity of hypertension can be increased when Orciprenaline is combined with Zomepirac.
Propofol The risk or severity of hypertension can be increased when Propofol is combined with Zomepirac.
Phenmetrazine The risk or severity of hypertension can be increased when Phenmetrazine is combined with Zomepirac.
Pseudoephedrine The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Zomepirac.
Ritodrine The risk or severity of hypertension can be increased when Ritodrine is combined with Zomepirac.
Remifentanil The risk or severity of hypertension can be increased when Remifentanil is combined with Zomepirac.
Bitolterol The risk or severity of hypertension can be increased when Bitolterol is combined with Zomepirac.
Oxymetazoline The risk or severity of hypertension can be increased when Oxymetazoline is combined with Zomepirac.
Diethylpropion The risk or severity of hypertension can be increased when Diethylpropion is combined with Zomepirac.
Naratriptan The risk or severity of hypertension can be increased when Naratriptan is combined with Zomepirac.
Formoterol The risk or severity of hypertension can be increased when Formoterol is combined with Zomepirac.
Frovatriptan The risk or severity of hypertension can be increased when Frovatriptan is combined with Zomepirac.
Isoprenaline The risk or severity of hypertension can be increased when Isoprenaline is combined with Zomepirac.
Arbutamine The risk or severity of hypertension can be increased when Arbutamine is combined with Zomepirac.
Moclobemide The risk or severity of hypertension can be increased when Moclobemide is combined with Zomepirac.
Desflurane The risk or severity of hypertension can be increased when Desflurane is combined with Zomepirac.
Isocarboxazid The risk or severity of hypertension can be increased when Isocarboxazid is combined with Zomepirac.
Lisdexamfetamine The risk or severity of hypertension can be increased when Lisdexamfetamine is combined with Zomepirac.
Fenoterol The risk or severity of hypertension can be increased when Fenoterol is combined with Zomepirac.
Pirbuterol The risk or severity of hypertension can be increased when Pirbuterol is combined with Zomepirac.
Ephedra sinica root The risk or severity of hypertension can be increased when Ephedra sinica root is combined with Zomepirac.
Ephedrine The risk or severity of hypertension can be increased when Ephedrine is combined with Zomepirac.
Mephentermine The risk or severity of hypertension can be increased when Mephentermine is combined with Zomepirac.
Procaterol The risk or severity of hypertension can be increased when Procaterol is combined with Zomepirac.
Methotrimeprazine The risk or severity of hypertension can be increased when Methotrimeprazine is combined with Zomepirac.
Clenbuterol The risk or severity of hypertension can be increased when Clenbuterol is combined with Zomepirac.
Bambuterol The risk or severity of hypertension can be increased when Bambuterol is combined with Zomepirac.
MMDA The risk or severity of hypertension can be increased when MMDA is combined with Zomepirac.
Midomafetamine The risk or severity of hypertension can be increased when Midomafetamine is combined with Zomepirac.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of hypertension can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Zomepirac.
4-Methoxyamphetamine The risk or severity of hypertension can be increased when 4-Methoxyamphetamine is combined with Zomepirac.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of hypertension can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Zomepirac.
Tenamfetamine The risk or severity of hypertension can be increased when Tenamfetamine is combined with Zomepirac.
Chlorphentermine The risk or severity of hypertension can be increased when Chlorphentermine is combined with Zomepirac.
Dextroamphetamine The risk or severity of hypertension can be increased when Dextroamphetamine is combined with Zomepirac.
Phendimetrazine The risk or severity of hypertension can be increased when Phendimetrazine is combined with Zomepirac.
Periciazine The risk or severity of hypertension can be increased when Periciazine is combined with Zomepirac.
Acepromazine The risk or severity of hypertension can be increased when Acepromazine is combined with Zomepirac.
Thioproperazine The risk or severity of hypertension can be increased when Thioproperazine is combined with Zomepirac.
Epicaptopril The risk or severity of hypertension can be increased when Epicaptopril is combined with Zomepirac.
Clorgiline The risk or severity of hypertension can be increased when Clorgiline is combined with Zomepirac.
1-benzylimidazole The risk or severity of hypertension can be increased when 1-benzylimidazole is combined with Zomepirac.
Iproniazid The risk or severity of hypertension can be increased when Iproniazid is combined with Zomepirac.
Nialamide The risk or severity of hypertension can be increased when Nialamide is combined with Zomepirac.
Amibegron The risk or severity of hypertension can be increased when Zomepirac is combined with Amibegron.
Naluzotan The risk or severity of hypertension can be increased when Zomepirac is combined with Naluzotan.
Pizotifen The risk or severity of hypertension can be increased when Zomepirac is combined with Pizotifen.
Solabegron The risk or severity of hypertension can be increased when Zomepirac is combined with Solabegron.
Esmirtazapine The risk or severity of hypertension can be increased when Zomepirac is combined with Esmirtazapine.
Nitrous oxide The risk or severity of hypertension can be increased when Zomepirac is combined with Nitrous oxide.
Xylometazoline The risk or severity of hypertension can be increased when Zomepirac is combined with Xylometazoline.
Dexmethylphenidate The risk or severity of hypertension can be increased when Zomepirac is combined with Dexmethylphenidate.
Isometheptene The risk or severity of hypertension can be increased when Zomepirac is combined with Isometheptene.
Levonordefrin The risk or severity of hypertension can be increased when Zomepirac is combined with Levonordefrin.
Naphazoline The risk or severity of hypertension can be increased when Zomepirac is combined with Naphazoline.
Tetryzoline The risk or severity of hypertension can be increased when Zomepirac is combined with Tetryzoline.
Cinitapride The risk or severity of hypertension can be increased when Zomepirac is combined with Cinitapride.
Tyramine The risk or severity of hypertension can be increased when Zomepirac is combined with Tyramine.
Adrafinil The risk or severity of hypertension can be increased when Zomepirac is combined with Adrafinil.
Isoxsuprine The risk or severity of hypertension can be increased when Zomepirac is combined with Isoxsuprine.
Ifenprodil The risk or severity of hypertension can be increased when Zomepirac is combined with Ifenprodil.
Hexoprenaline The risk or severity of hypertension can be increased when Zomepirac is combined with Hexoprenaline.
Etilefrine The risk or severity of hypertension can be increased when Zomepirac is combined with Etilefrine.
Olodaterol The risk or severity of hypertension can be increased when Zomepirac is combined with Olodaterol.
Cirazoline The risk or severity of hypertension can be increased when Zomepirac is combined with Cirazoline.
Synephrine The risk or severity of hypertension can be increased when Zomepirac is combined with Synephrine.
Hydracarbazine The risk or severity of hypertension can be increased when Zomepirac is combined with Hydracarbazine.
Benmoxin The risk or severity of hypertension can be increased when Zomepirac is combined with Benmoxin.
Mebanazine The risk or severity of hypertension can be increased when Zomepirac is combined with Mebanazine.
Octamoxin The risk or severity of hypertension can be increased when Zomepirac is combined with Octamoxin.
Pheniprazine The risk or severity of hypertension can be increased when Zomepirac is combined with Pheniprazine.
Phenoxypropazine The risk or severity of hypertension can be increased when Zomepirac is combined with Phenoxypropazine.
Pivhydrazine The risk or severity of hypertension can be increased when Zomepirac is combined with Pivhydrazine.
Safrazine The risk or severity of hypertension can be increased when Zomepirac is combined with Safrazine.
Caroxazone The risk or severity of hypertension can be increased when Zomepirac is combined with Caroxazone.
Doxofylline The risk or severity of hypertension can be increased when Zomepirac is combined with Doxofylline.
Iofetamine I-123 The risk or severity of hypertension can be increased when Zomepirac is combined with Iofetamine I-123.
Racepinephrine The risk or severity of hypertension can be increased when Zomepirac is combined with Racepinephrine.
Amitraz The risk or severity of hypertension can be increased when Zomepirac is combined with Amitraz.
Medetomidine The risk or severity of hypertension can be increased when Zomepirac is combined with Medetomidine.
Xylazine The risk or severity of hypertension can be increased when Zomepirac is combined with Xylazine.

Target Protein

Prostaglandin G/H synthase 1 PTGS1
Prostaglandin G/H synthase 2 PTGS2
Prostaglandin D2 receptor 2 PTGDR2

Referensi & Sumber

Synthesis reference: James B. Doherty, Debra L. Allison, "Process for the preparation of zomepirac and related compounds." U.S. Patent US4374997, issued January, 1978.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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