Peringatan Keamanan

Oral rat LD50: 10080 mg/kg. Intravenous mouse LD50: 600 mg/kg. Skin rabbit LD50: over 5000 mg/kg.

Caprylic acid

DB04519

small molecule investigational

Deskripsi

Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid-like smell that is minimally soluble in water.

Struktur Molekul 2D

Berat 144.2114
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

80 Data
Succinic acid The excretion of Succinic acid can be decreased when combined with Caprylic acid.
Citrulline The excretion of Citrulline can be decreased when combined with Caprylic acid.
Pravastatin The excretion of Pravastatin can be decreased when combined with Caprylic acid.
Oseltamivir The excretion of Oseltamivir can be decreased when combined with Caprylic acid.
Cefotiam The excretion of Cefotiam can be decreased when combined with Caprylic acid.
Conjugated estrogens The excretion of Conjugated estrogens can be decreased when combined with Caprylic acid.
Tenofovir disoproxil The excretion of Tenofovir disoproxil can be decreased when combined with Caprylic acid.
Piperacillin The excretion of Piperacillin can be decreased when combined with Caprylic acid.
Indomethacin The excretion of Indomethacin can be decreased when combined with Caprylic acid.
Aminohippuric acid The excretion of Aminohippuric acid can be decreased when combined with Caprylic acid.
Trifluridine The excretion of Trifluridine can be decreased when combined with Caprylic acid.
Allopurinol The excretion of Allopurinol can be decreased when combined with Caprylic acid.
Zidovudine The excretion of Zidovudine can be decreased when combined with Caprylic acid.
Cimetidine The excretion of Cimetidine can be decreased when combined with Caprylic acid.
Cefdinir The excretion of Cefdinir can be decreased when combined with Caprylic acid.
Methotrexate The excretion of Methotrexate can be decreased when combined with Caprylic acid.
Cephalexin The excretion of Cephalexin can be decreased when combined with Caprylic acid.
Valaciclovir The excretion of Valaciclovir can be decreased when combined with Caprylic acid.
Levocarnitine The excretion of Levocarnitine can be decreased when combined with Caprylic acid.
Leucovorin The excretion of Leucovorin can be decreased when combined with Caprylic acid.
Fluorescein The excretion of Fluorescein can be decreased when combined with Caprylic acid.
Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Caprylic acid.
Tetracycline The excretion of Tetracycline can be decreased when combined with Caprylic acid.
Estradiol The excretion of Estradiol can be decreased when combined with Caprylic acid.
Acyclovir The excretion of Acyclovir can be decreased when combined with Caprylic acid.
Cefaclor The excretion of Cefaclor can be decreased when combined with Caprylic acid.
Ranitidine The excretion of Ranitidine can be decreased when combined with Caprylic acid.
Quinapril The excretion of Quinapril can be decreased when combined with Caprylic acid.
Bumetanide The excretion of Bumetanide can be decreased when combined with Caprylic acid.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Caprylic acid.
Famotidine The excretion of Famotidine can be decreased when combined with Caprylic acid.
Fexofenadine The excretion of Fexofenadine can be decreased when combined with Caprylic acid.
Benzylpenicillin The excretion of Benzylpenicillin can be decreased when combined with Caprylic acid.
Rosuvastatin The excretion of Rosuvastatin can be decreased when combined with Caprylic acid.
Captopril The excretion of Captopril can be decreased when combined with Caprylic acid.
Sitagliptin The excretion of Sitagliptin can be decreased when combined with Caprylic acid.
Cefazolin The excretion of Cefazolin can be decreased when combined with Caprylic acid.
Ceftizoxime The excretion of Ceftizoxime can be decreased when combined with Caprylic acid.
Cefacetrile The excretion of Cefacetrile can be decreased when combined with Caprylic acid.
Ceftibuten The excretion of Ceftibuten can be decreased when combined with Caprylic acid.
Tazobactam The excretion of Tazobactam can be decreased when combined with Caprylic acid.
Cyclic adenosine monophosphate The excretion of Cyclic adenosine monophosphate can be decreased when combined with Caprylic acid.
Cholic Acid The excretion of Cholic Acid can be decreased when combined with Caprylic acid.
Glutaric Acid The excretion of Glutaric Acid can be decreased when combined with Caprylic acid.
Oxalic Acid The excretion of Oxalic Acid can be decreased when combined with Caprylic acid.
Taurocholic acid The excretion of Taurocholic acid can be decreased when combined with Caprylic acid.
Doripenem The excretion of Doripenem can be decreased when combined with Caprylic acid.
Saxagliptin The excretion of Saxagliptin can be decreased when combined with Caprylic acid.
Ellagic acid The excretion of Ellagic acid can be decreased when combined with Caprylic acid.
Cefaloridine The excretion of Cefaloridine can be decreased when combined with Caprylic acid.
Avibactam The excretion of Avibactam can be decreased when combined with Caprylic acid.
Eluxadoline The excretion of Eluxadoline can be decreased when combined with Caprylic acid.
Silibinin The excretion of Silibinin can be decreased when combined with Caprylic acid.
Tenofovir alafenamide The excretion of Tenofovir alafenamide can be decreased when combined with Caprylic acid.
Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Caprylic acid.
Relebactam The excretion of Relebactam can be decreased when combined with Caprylic acid.
Tenofovir The excretion of Tenofovir can be decreased when combined with Caprylic acid.
Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Caprylic acid.
Dexamethasone The excretion of Dexamethasone can be decreased when combined with Caprylic acid.
Oxytetracycline The excretion of Oxytetracycline can be decreased when combined with Caprylic acid.
Polythiazide The excretion of Polythiazide can be decreased when combined with Caprylic acid.
Prednisolone phosphate The excretion of Prednisolone phosphate can be decreased when combined with Caprylic acid.
Dexamethasone acetate The excretion of Dexamethasone acetate can be decreased when combined with Caprylic acid.
Acamprosate The excretion of Acamprosate can be decreased when combined with Caprylic acid.
Pemetrexed Caprylic acid may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Caprylic acid.
Valproic acid The excretion of Valproic acid can be decreased when combined with Caprylic acid.
Clofarabine The excretion of Clofarabine can be decreased when combined with Caprylic acid.
Grepafloxacin The excretion of Grepafloxacin can be decreased when combined with Caprylic acid.
Cidofovir The excretion of Cidofovir can be decreased when combined with Caprylic acid.
Stavudine The excretion of Stavudine can be decreased when combined with Caprylic acid.
Lamivudine The excretion of Lamivudine can be decreased when combined with Caprylic acid.
Adefovir dipivoxil The excretion of Adefovir dipivoxil can be decreased when combined with Caprylic acid.
Didanosine The excretion of Didanosine can be decreased when combined with Caprylic acid.
Zalcitabine The excretion of Zalcitabine can be decreased when combined with Caprylic acid.
Levofloxacin The excretion of Levofloxacin can be decreased when combined with Caprylic acid.
Vadadustat The serum concentration of Vadadustat can be increased when it is combined with Caprylic acid.
Sulbactam The excretion of Sulbactam can be decreased when combined with Caprylic acid.
Seladelpar The excretion of Seladelpar can be decreased when combined with Caprylic acid.
Sulopenem etzadroxil The serum concentration of Sulopenem etzadroxil can be increased when it is combined with Caprylic acid.

Target Protein

Peroxisome proliferator-activated receptor alpha PPARA
3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB
Acyl-CoA thioesterase I tesA

Referensi & Sumber

Synthesis reference: William Elliott Bay, Joseph Norman Bernadino, George Frederick Klein, Yi Ren, Pingsheng Zhang, "METHODS FOR PRODUCING N-(8-2-HYDROXYBENZOYL-AMINO) CAPRYLIC ACID." U.S. Patent US20080064890, issued March 13, 2008.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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