6-Deoxyerythronolide B

DB04070

small molecule experimental

Deskripsi

Struktur Molekul 2D

Berat 386.5228
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

315 Data
Eliglustat The metabolism of Eliglustat can be decreased when combined with 6-Deoxyerythronolide B.
Ibrutinib The metabolism of Ibrutinib can be decreased when combined with 6-Deoxyerythronolide B.
Alfentanil The serum concentration of Alfentanil can be increased when it is combined with 6-Deoxyerythronolide B.
Buspirone The metabolism of Buspirone can be decreased when combined with 6-Deoxyerythronolide B.
Carbamazepine The metabolism of Carbamazepine can be decreased when combined with 6-Deoxyerythronolide B.
Cisapride The serum concentration of Cisapride can be increased when it is combined with 6-Deoxyerythronolide B.
Disopyramide 6-Deoxyerythronolide B may increase the QTc-prolonging activities of Disopyramide.
Estazolam The serum concentration of Estazolam can be increased when it is combined with 6-Deoxyerythronolide B.
Quinine The serum concentration of Quinine can be increased when it is combined with 6-Deoxyerythronolide B.
Quinidine The serum concentration of Quinidine can be increased when it is combined with 6-Deoxyerythronolide B.
Repaglinide The serum concentration of Repaglinide can be increased when it is combined with 6-Deoxyerythronolide B.
Sirolimus The metabolism of Sirolimus can be decreased when combined with 6-Deoxyerythronolide B.
Temsirolimus The metabolism of Temsirolimus can be decreased when combined with 6-Deoxyerythronolide B.
Terfenadine The serum concentration of Terfenadine can be increased when it is combined with 6-Deoxyerythronolide B.
Triazolam The serum concentration of Triazolam can be increased when it is combined with 6-Deoxyerythronolide B.
Cilostazol The metabolism of Cilostazol can be decreased when combined with 6-Deoxyerythronolide B.
Colchicine The metabolism of Colchicine can be decreased when combined with 6-Deoxyerythronolide B.
Iloperidone The metabolism of Iloperidone can be decreased when combined with 6-Deoxyerythronolide B.
Retapamulin The metabolism of Retapamulin can be decreased when combined with 6-Deoxyerythronolide B.
Tofacitinib The metabolism of Tofacitinib can be decreased when combined with 6-Deoxyerythronolide B.
Vardenafil The metabolism of Vardenafil can be decreased when combined with 6-Deoxyerythronolide B.
Eszopiclone The metabolism of Eszopiclone can be decreased when combined with 6-Deoxyerythronolide B.
Zopiclone The metabolism of Zopiclone can be decreased when combined with 6-Deoxyerythronolide B.
Lovastatin The metabolism of Lovastatin can be decreased when combined with 6-Deoxyerythronolide B.
Alfuzosin The metabolism of Alfuzosin can be decreased when combined with 6-Deoxyerythronolide B.
Alprazolam The serum concentration of Alprazolam can be increased when it is combined with 6-Deoxyerythronolide B.
Warfarin The serum concentration of Warfarin can be increased when it is combined with 6-Deoxyerythronolide B.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with 6-Deoxyerythronolide B.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with 6-Deoxyerythronolide B.
R,S-Warfarin alcohol The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with 6-Deoxyerythronolide B.
S,R-Warfarin alcohol The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with 6-Deoxyerythronolide B.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with 6-Deoxyerythronolide B.
Midazolam The serum concentration of Midazolam can be increased when it is combined with 6-Deoxyerythronolide B.
Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with 6-Deoxyerythronolide B.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with 6-Deoxyerythronolide B.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with 6-Deoxyerythronolide B.
Vintafolide The serum concentration of Vintafolide can be increased when it is combined with 6-Deoxyerythronolide B.
Vincamine The serum concentration of Vincamine can be increased when it is combined with 6-Deoxyerythronolide B.
Acetyldigitoxin The serum concentration of Acetyldigitoxin can be increased when it is combined with 6-Deoxyerythronolide B.
Deslanoside The serum concentration of Deslanoside can be increased when it is combined with 6-Deoxyerythronolide B.
Ouabain The serum concentration of Ouabain can be increased when it is combined with 6-Deoxyerythronolide B.
Oleandrin The serum concentration of Oleandrin can be increased when it is combined with 6-Deoxyerythronolide B.
Cymarin The serum concentration of Cymarin can be increased when it is combined with 6-Deoxyerythronolide B.
Proscillaridin The serum concentration of Proscillaridin can be increased when it is combined with 6-Deoxyerythronolide B.
Metildigoxin The serum concentration of Metildigoxin can be increased when it is combined with 6-Deoxyerythronolide B.
Lanatoside C The serum concentration of Lanatoside C can be increased when it is combined with 6-Deoxyerythronolide B.
Gitoformate The serum concentration of Gitoformate can be increased when it is combined with 6-Deoxyerythronolide B.
Acetyldigoxin The serum concentration of Acetyldigoxin can be increased when it is combined with 6-Deoxyerythronolide B.
Peruvoside The serum concentration of Peruvoside can be increased when it is combined with 6-Deoxyerythronolide B.
Cyclosporine The metabolism of Cyclosporine can be decreased when combined with 6-Deoxyerythronolide B.
Dicoumarol The serum concentration of Dicoumarol can be increased when it is combined with 6-Deoxyerythronolide B.
Phenindione The serum concentration of Phenindione can be increased when it is combined with 6-Deoxyerythronolide B.
Coumarin The serum concentration of Coumarin can be increased when it is combined with 6-Deoxyerythronolide B.
Tioclomarol The serum concentration of Tioclomarol can be increased when it is combined with 6-Deoxyerythronolide B.
Ethyl biscoumacetate The serum concentration of Ethyl biscoumacetate can be increased when it is combined with 6-Deoxyerythronolide B.
Diphenadione The serum concentration of Diphenadione can be increased when it is combined with 6-Deoxyerythronolide B.
4-hydroxycoumarin The serum concentration of 4-hydroxycoumarin can be increased when it is combined with 6-Deoxyerythronolide B.
Fluindione The serum concentration of Fluindione can be increased when it is combined with 6-Deoxyerythronolide B.
Clorindione The serum concentration of Clorindione can be increased when it is combined with 6-Deoxyerythronolide B.
Oxtriphylline The metabolism of Oxtriphylline can be decreased when combined with 6-Deoxyerythronolide B.
Doxofylline The metabolism of Doxofylline can be decreased when combined with 6-Deoxyerythronolide B.
Bamifylline The metabolism of Bamifylline can be decreased when combined with 6-Deoxyerythronolide B.
Acefylline The metabolism of Acefylline can be decreased when combined with 6-Deoxyerythronolide B.
Bufylline The metabolism of Bufylline can be decreased when combined with 6-Deoxyerythronolide B.
Fenethylline The metabolism of Fenethylline can be decreased when combined with 6-Deoxyerythronolide B.
Proxyphylline The metabolism of Proxyphylline can be decreased when combined with 6-Deoxyerythronolide B.
Bromotheophylline The metabolism of Bromotheophylline can be decreased when combined with 6-Deoxyerythronolide B.
Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with 6-Deoxyerythronolide B.
8-azaguanine The metabolism of 8-azaguanine can be decreased when combined with 6-Deoxyerythronolide B.
7,9-Dimethylguanine The metabolism of 7,9-Dimethylguanine can be decreased when combined with 6-Deoxyerythronolide B.
Xanthine The metabolism of Xanthine can be decreased when combined with 6-Deoxyerythronolide B.
7-Deazaguanine The metabolism of 7-Deazaguanine can be decreased when combined with 6-Deoxyerythronolide B.
Guanine The metabolism of Guanine can be decreased when combined with 6-Deoxyerythronolide B.
9-Methylguanine The metabolism of 9-Methylguanine can be decreased when combined with 6-Deoxyerythronolide B.
Peldesine The metabolism of Peldesine can be decreased when combined with 6-Deoxyerythronolide B.
Hypoxanthine The metabolism of Hypoxanthine can be decreased when combined with 6-Deoxyerythronolide B.
9-Deazaguanine The metabolism of 9-Deazaguanine can be decreased when combined with 6-Deoxyerythronolide B.
Valomaciclovir The metabolism of Valomaciclovir can be decreased when combined with 6-Deoxyerythronolide B.
3-isobutyl-1-methyl-7H-xanthine The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with 6-Deoxyerythronolide B.
Uric acid The metabolism of Uric acid can be decreased when combined with 6-Deoxyerythronolide B.
6-O-benzylguanine The metabolism of 6-O-benzylguanine can be decreased when combined with 6-Deoxyerythronolide B.
Lisofylline The metabolism of Lisofylline can be decreased when combined with 6-Deoxyerythronolide B.
Lobucavir The metabolism of Lobucavir can be decreased when combined with 6-Deoxyerythronolide B.
Cafedrine The metabolism of Cafedrine can be decreased when combined with 6-Deoxyerythronolide B.
Theodrenaline The metabolism of Theodrenaline can be decreased when combined with 6-Deoxyerythronolide B.
Etamiphylline The metabolism of Etamiphylline can be decreased when combined with 6-Deoxyerythronolide B.
Pentifylline The metabolism of Pentifylline can be decreased when combined with 6-Deoxyerythronolide B.
Furafylline The metabolism of Furafylline can be decreased when combined with 6-Deoxyerythronolide B.
Theobromine The metabolism of Theobromine can be decreased when combined with 6-Deoxyerythronolide B.
Propentofylline The metabolism of Propentofylline can be decreased when combined with 6-Deoxyerythronolide B.
Caffeine The metabolism of Caffeine can be decreased when combined with 6-Deoxyerythronolide B.
8-chlorotheophylline The metabolism of 8-chlorotheophylline can be decreased when combined with 6-Deoxyerythronolide B.
Mercaptopurine The metabolism of Mercaptopurine can be decreased when combined with 6-Deoxyerythronolide B.
PCS-499 The metabolism of PCS-499 can be decreased when combined with 6-Deoxyerythronolide B.
Methylergometrine The serum concentration of Methylergometrine can be increased when it is combined with 6-Deoxyerythronolide B.
Lisuride The serum concentration of Lisuride can be increased when it is combined with 6-Deoxyerythronolide B.
Nicergoline The serum concentration of Nicergoline can be increased when it is combined with 6-Deoxyerythronolide B.
Ergoloid mesylate The serum concentration of Ergoloid mesylate can be increased when it is combined with 6-Deoxyerythronolide B.
Pergolide The serum concentration of Pergolide can be increased when it is combined with 6-Deoxyerythronolide B.
Ergometrine The serum concentration of Ergometrine can be increased when it is combined with 6-Deoxyerythronolide B.

Target Protein

6-deoxyerythronolide B hydroxylase eryF

Referensi & Sumber

Synthesis reference: Robert McDaniel, "Production of 8,8a-dihydroxy-6-deoxyerythronolide B." U.S. Patent US20010034046, issued October 25, 2001.

Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

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