4-hydroxycoumarin

DB03410

small molecule experimental

Deskripsi

Struktur Molekul 2D

Berat 162.144
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1294 Data
Apixaban Apixaban may increase the anticoagulant activities of 4-hydroxycoumarin.
Dabigatran etexilate Dabigatran etexilate may increase the anticoagulant activities of 4-hydroxycoumarin.
Dasatinib The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with 4-hydroxycoumarin.
Deferasirox The risk or severity of gastrointestinal bleeding can be increased when 4-hydroxycoumarin is combined with Deferasirox.
Ursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Ursodeoxycholic acid.
Glycochenodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Glycochenodeoxycholic Acid.
Cholic Acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Cholic Acid.
Glycocholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Glycocholic acid.
Deoxycholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Deoxycholic acid.
Taurocholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Taurocholic acid.
Obeticholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Obeticholic acid.
Chenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Chenodeoxycholic acid.
Taurochenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Taurochenodeoxycholic acid.
Tauroursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Tauroursodeoxycholic acid.
Bamet-UD2 The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Bamet-UD2.
Dehydrocholic acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Dehydrocholic acid.
Hyodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Hyodeoxycholic Acid.
Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with 4-hydroxycoumarin.
Ibrutinib The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with 4-hydroxycoumarin.
Obinutuzumab The risk or severity of bleeding and hemorrhage can be increased when 4-hydroxycoumarin is combined with Obinutuzumab.
Rivaroxaban 4-hydroxycoumarin may increase the anticoagulant activities of Rivaroxaban.
Sugammadex The risk or severity of bleeding and hemorrhage can be increased when 4-hydroxycoumarin is combined with Sugammadex.
Tibolone Tibolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Tipranavir The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with 4-hydroxycoumarin.
Urokinase Urokinase may increase the anticoagulant activities of 4-hydroxycoumarin.
Vitamin E Vitamin E may increase the anticoagulant activities of 4-hydroxycoumarin.
Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Vorapaxar is combined with 4-hydroxycoumarin.
Gemcitabine The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Gemcitabine.
Flunisolide Flunisolide may increase the anticoagulant activities of 4-hydroxycoumarin.
Beclomethasone dipropionate Beclomethasone dipropionate may increase the anticoagulant activities of 4-hydroxycoumarin.
Betamethasone Betamethasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluticasone propionate Fluticasone propionate may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluocinolone acetonide Fluocinolone acetonide may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisone Prednisone may increase the anticoagulant activities of 4-hydroxycoumarin.
Fludrocortisone Fludrocortisone may increase the anticoagulant activities of 4-hydroxycoumarin.
Hydrocortisone Hydrocortisone may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisolone Prednisolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Methylprednisolone Methylprednisolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Trilostane Trilostane may increase the anticoagulant activities of 4-hydroxycoumarin.
Budesonide Budesonide may increase the anticoagulant activities of 4-hydroxycoumarin.
Dexamethasone Dexamethasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Corticotropin Corticotropin may increase the anticoagulant activities of 4-hydroxycoumarin.
Cortisone acetate Cortisone acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Paramethasone Paramethasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Ciclesonide Ciclesonide may increase the anticoagulant activities of 4-hydroxycoumarin.
Aldosterone Aldosterone may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluticasone furoate Fluticasone furoate may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluprednidene Fluprednidene may increase the anticoagulant activities of 4-hydroxycoumarin.
Tixocortol Tixocortol may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluprednisolone Fluprednisolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Meprednisone Meprednisone may increase the anticoagulant activities of 4-hydroxycoumarin.
Dexamethasone isonicotinate Dexamethasone isonicotinate may increase the anticoagulant activities of 4-hydroxycoumarin.
Melengestrol Melengestrol may increase the anticoagulant activities of 4-hydroxycoumarin.
Deflazacort Deflazacort may increase the anticoagulant activities of 4-hydroxycoumarin.
Cortivazol Cortivazol may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednylidene Prednylidene may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluocortin Fluocortin may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluperolone Fluperolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Cloprednol Cloprednol may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluclorolone Fluclorolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluticasone Fluticasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Mometasone furoate Mometasone furoate may increase the anticoagulant activities of 4-hydroxycoumarin.
Hydrocortisone acetate Hydrocortisone acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Hydrocortisone cypionate Hydrocortisone cypionate may increase the anticoagulant activities of 4-hydroxycoumarin.
Hydrocortisone succinate Hydrocortisone succinate may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisolone phosphate Prednisolone phosphate may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisolone hemisuccinate Prednisolone hemisuccinate may increase the anticoagulant activities of 4-hydroxycoumarin.
Methylprednisolone hemisuccinate Methylprednisolone hemisuccinate may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisone acetate Prednisone acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Clocortolone acetate Clocortolone acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Melengestrol acetate Melengestrol acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Betamethasone phosphate Betamethasone phosphate may increase the anticoagulant activities of 4-hydroxycoumarin.
Cortisone Cortisone may increase the anticoagulant activities of 4-hydroxycoumarin.
Clobetasol propionate Clobetasol propionate may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluocinonide Fluocinonide may increase the anticoagulant activities of 4-hydroxycoumarin.
Hydrocortisone butyrate Hydrocortisone butyrate may increase the anticoagulant activities of 4-hydroxycoumarin.
Desoximetasone Desoximetasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Mometasone Mometasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluocortolone Fluocortolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Prednisolone acetate Prednisolone acetate may increase the anticoagulant activities of 4-hydroxycoumarin.
Fluorometholone Fluorometholone may increase the anticoagulant activities of 4-hydroxycoumarin.
Difluocortolone Difluocortolone may increase the anticoagulant activities of 4-hydroxycoumarin.
Flumethasone Flumethasone may increase the anticoagulant activities of 4-hydroxycoumarin.
Methylprednisolone aceponate Methylprednisolone aceponate may increase the anticoagulant activities of 4-hydroxycoumarin.
Erlotinib The serum concentration of 4-hydroxycoumarin can be increased when it is combined with Erlotinib.
Acetaminophen Acetaminophen may increase the anticoagulant activities of 4-hydroxycoumarin.
Allopurinol The risk or severity of bleeding can be increased when Allopurinol is combined with 4-hydroxycoumarin.
Azathioprine The therapeutic efficacy of 4-hydroxycoumarin can be decreased when used in combination with Azathioprine.
Chloral hydrate The protein binding of 4-hydroxycoumarin can be decreased when combined with Chloral hydrate.
Methylphenidate The metabolism of 4-hydroxycoumarin can be decreased when combined with Methylphenidate.
Disulfiram Disulfiram may increase the anticoagulant activities of 4-hydroxycoumarin.
Etacrynic acid The protein binding of 4-hydroxycoumarin can be decreased when combined with Etacrynic acid.
Ethotoin The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Ethotoin.
Etoposide The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Etoposide.
Exenatide Exenatide can cause an increase in the absorption of 4-hydroxycoumarin resulting in an increased serum concentration and potentially a worsening of adverse effects.
Gefitinib Gefitinib may increase the anticoagulant activities of 4-hydroxycoumarin.
Ginkgo biloba Ginkgo biloba may increase the anticoagulant activities of 4-hydroxycoumarin.
Glutethimide The therapeutic efficacy of 4-hydroxycoumarin can be decreased when used in combination with Glutethimide.
Ifosfamide The risk or severity of bleeding can be increased when Ifosfamide is combined with 4-hydroxycoumarin.
Leflunomide The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Leflunomide.

Target Protein

Major NAD(P)H-flavin oxidoreductase

Referensi & Sumber

Synthesis reference: Nasri W. Badran, "Microcrystalline 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin (warfarin) and methods of making." U.S. Patent US4113744, issued April, 1960.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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