(6R)-Folinic acid

DB03256

small molecule experimental

Deskripsi

Struktur Molekul 2D

Berat 473.4393
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

18 Data
Fosphenytoin The serum concentration of Fosphenytoin can be decreased when it is combined with (6R)-Folinic acid.
Raltitrexed The therapeutic efficacy of Raltitrexed can be decreased when used in combination with (6R)-Folinic acid.
Sulfasalazine The serum concentration of (6R)-Folinic acid can be decreased when it is combined with Sulfasalazine.
Phenytoin The serum concentration of Phenytoin can be decreased when it is combined with (6R)-Folinic acid.
Glucarpidase The serum concentration of the active metabolites of (6R)-Folinic acid can be reduced when (6R)-Folinic acid is used in combination with Glucarpidase resulting in a loss in efficacy.
Phenobarbital The serum concentration of Phenobarbital can be decreased when it is combined with (6R)-Folinic acid.
Primidone The serum concentration of Primidone can be decreased when it is combined with (6R)-Folinic acid.
Valproic acid The serum concentration of (6R)-Folinic acid can be decreased when it is combined with Valproic acid.
Colestipol The serum concentration of (6R)-Folinic acid can be decreased when it is combined with Colestipol.
Carbamazepine The serum concentration of (6R)-Folinic acid can be decreased when it is combined with Carbamazepine.
Fluorouracil The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Fluorouracil.
Flucytosine The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Flucytosine.
Capecitabine The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Capecitabine.
5-fluorouridine The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with 5-fluorouridine.
Uracil The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Uracil.
Tegafur The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Tegafur.
Doxifluridine The risk or severity of adverse effects can be increased when (6R)-Folinic acid is combined with Doxifluridine.
Pafolacianine (6R)-Folinic acid may decrease effectiveness of Pafolacianine as a diagnostic agent.

Target Protein

Serine hydroxymethyltransferase glyA
Aminomethyltransferase gcvT
Bifunctional polymyxin resistance protein ArnA arnA
Formimidoyltransferase-cyclodeaminase FTCD
Dimethylglycine oxidase dmg

Referensi & Sumber

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Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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