Mouse, Subcutaneous, LD50: 0.3-0.35 g/kg. (Duplay and Cazin, 1891; Tollens, 1905).
Rat, Subcutaneous, LD50: 0.45. (Deichmann and Witherup, 1944).
Rat, Oral, LD50: 0.53. (Deichmann and Witherup, 1944).
Rat, Oral, LD50: 0.65. (Flickinger, 1976).
Rat, Cutaneous, LD50: 0.67. (Conning and Hayes, 1970).
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization. Research indicates that parental exposure to phenol and its related compounds are positively associated with spontaneous abortion. During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Hyaluronidase (ovine) | Hyaluronidase (ovine) can cause an increase in the absorption of Phenol resulting in an increased serum concentration and potentially a worsening of adverse effects. |
| Hyaluronidase (human recombinant) | Hyaluronidase (human recombinant) can cause an increase in the absorption of Phenol resulting in an increased serum concentration and potentially a worsening of adverse effects. |
| Hyaluronidase | Hyaluronidase can cause an increase in the absorption of Phenol resulting in an increased serum concentration and potentially a worsening of adverse effects. |
| Technetium Tc-99m tilmanocept | Phenol may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent. |
| Chloroprocaine | The risk or severity of adverse effects can be increased when Phenol is combined with Chloroprocaine. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when Lidocaine is combined with Phenol. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when Ropivacaine is combined with Phenol. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when Bupivacaine is combined with Phenol. |
| Cinchocaine | The risk or severity of methemoglobinemia can be increased when Cinchocaine is combined with Phenol. |
| Dyclonine | The risk or severity of methemoglobinemia can be increased when Dyclonine is combined with Phenol. |
| Procaine | The risk or severity of methemoglobinemia can be increased when Procaine is combined with Phenol. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Prilocaine is combined with Phenol. |
| Proparacaine | The risk or severity of methemoglobinemia can be increased when Proparacaine is combined with Phenol. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when Meloxicam is combined with Phenol. |
| Oxybuprocaine | The risk or severity of methemoglobinemia can be increased when Oxybuprocaine is combined with Phenol. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when Cocaine is combined with Phenol. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when Mepivacaine is combined with Phenol. |
| Levobupivacaine | The risk or severity of methemoglobinemia can be increased when Levobupivacaine is combined with Phenol. |
| Diphenhydramine | The risk or severity of methemoglobinemia can be increased when Diphenhydramine is combined with Phenol. |
| Tetrodotoxin | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Tetrodotoxin. |
| Benzyl alcohol | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Benzyl alcohol. |
| Capsaicin | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Capsaicin. |
| Etidocaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Etidocaine. |
| Articaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Tetracaine. |
| Propoxycaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Propoxycaine. |
| Pramocaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Pramocaine. |
| Butamben | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Butamben. |
| Butacaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Butacaine. |
| Oxetacaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Oxetacaine. |
| Ethyl chloride | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Ethyl chloride. |
| Butanilicaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Butanilicaine. |
| Metabutethamine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Metabutethamine. |
| Quinisocaine | The risk or severity of methemoglobinemia can be increased when Phenol is combined with Quinisocaine. |
| Cetuximab | The risk or severity of methemoglobinemia can be increased when Cetuximab is combined with Phenol. |
| Denileukin diftitox | The risk or severity of methemoglobinemia can be increased when Denileukin diftitox is combined with Phenol. |
| Leuprolide | The risk or severity of methemoglobinemia can be increased when Leuprolide is combined with Phenol. |
| Peginterferon alfa-2a | The risk or severity of methemoglobinemia can be increased when Peginterferon alfa-2a is combined with Phenol. |
| Goserelin | The risk or severity of methemoglobinemia can be increased when Goserelin is combined with Phenol. |
| Asparaginase Escherichia coli | The risk or severity of methemoglobinemia can be increased when Asparaginase Escherichia coli is combined with Phenol. |
| Interferon alfa-2a | The risk or severity of methemoglobinemia can be increased when Interferon alfa-2a is combined with Phenol. |
| Aldesleukin | The risk or severity of methemoglobinemia can be increased when Aldesleukin is combined with Phenol. |
| Gemtuzumab ozogamicin | The risk or severity of methemoglobinemia can be increased when Gemtuzumab ozogamicin is combined with Phenol. |
| Pegaspargase | The risk or severity of methemoglobinemia can be increased when Pegaspargase is combined with Phenol. |
| Trastuzumab | The risk or severity of methemoglobinemia can be increased when Trastuzumab is combined with Phenol. |
| Rituximab | The risk or severity of methemoglobinemia can be increased when Rituximab is combined with Phenol. |
| Tositumomab | The risk or severity of methemoglobinemia can be increased when Tositumomab is combined with Phenol. |
| Alemtuzumab | The risk or severity of methemoglobinemia can be increased when Alemtuzumab is combined with Phenol. |
| Octreotide | The risk or severity of methemoglobinemia can be increased when Octreotide is combined with Phenol. |
| Interferon alfa-2b | The risk or severity of methemoglobinemia can be increased when Interferon alfa-2b is combined with Phenol. |
| Bevacizumab | The risk or severity of methemoglobinemia can be increased when Bevacizumab is combined with Phenol. |
| Masoprocol | The risk or severity of methemoglobinemia can be increased when Masoprocol is combined with Phenol. |
| Bortezomib | The risk or severity of methemoglobinemia can be increased when Bortezomib is combined with Phenol. |
| Pipobroman | The risk or severity of methemoglobinemia can be increased when Pipobroman is combined with Phenol. |
| Cladribine | The risk or severity of methemoglobinemia can be increased when Cladribine is combined with Phenol. |
| Cabergoline | The risk or severity of methemoglobinemia can be increased when Cabergoline is combined with Phenol. |
| Anagrelide | The risk or severity of methemoglobinemia can be increased when Anagrelide is combined with Phenol. |
| Carmustine | The risk or severity of methemoglobinemia can be increased when Carmustine is combined with Phenol. |
| Chlorotrianisene | The risk or severity of methemoglobinemia can be increased when Chlorotrianisene is combined with Phenol. |
| Amsacrine | The risk or severity of methemoglobinemia can be increased when Amsacrine is combined with Phenol. |
| Pamidronic acid | The risk or severity of methemoglobinemia can be increased when Pamidronic acid is combined with Phenol. |
| Bleomycin | The risk or severity of methemoglobinemia can be increased when Bleomycin is combined with Phenol. |
| Chlorambucil | The risk or severity of methemoglobinemia can be increased when Chlorambucil is combined with Phenol. |
| Raltitrexed | The risk or severity of methemoglobinemia can be increased when Raltitrexed is combined with Phenol. |
| Mitomycin | The risk or severity of methemoglobinemia can be increased when Mitomycin is combined with Phenol. |
| Bexarotene | The risk or severity of methemoglobinemia can be increased when Bexarotene is combined with Phenol. |
| Vindesine | The risk or severity of methemoglobinemia can be increased when Vindesine is combined with Phenol. |
| Valproic acid | The risk or severity of methemoglobinemia can be increased when Valproic acid is combined with Phenol. |
| Gefitinib | The risk or severity of methemoglobinemia can be increased when Gefitinib is combined with Phenol. |
| Floxuridine | The risk or severity of methemoglobinemia can be increased when Floxuridine is combined with Phenol. |
| Megestrol acetate | The risk or severity of methemoglobinemia can be increased when Megestrol acetate is combined with Phenol. |
| Tioguanine | The risk or severity of methemoglobinemia can be increased when Tioguanine is combined with Phenol. |
| Aminoglutethimide | The risk or severity of methemoglobinemia can be increased when Aminoglutethimide is combined with Phenol. |
| Vinorelbine | The risk or severity of methemoglobinemia can be increased when Vinorelbine is combined with Phenol. |
| Valrubicin | The risk or severity of methemoglobinemia can be increased when Valrubicin is combined with Phenol. |
| Sorafenib | The risk or severity of methemoglobinemia can be increased when Sorafenib is combined with Phenol. |
| Streptozocin | The risk or severity of methemoglobinemia can be increased when Streptozocin is combined with Phenol. |
| Trifluridine | The risk or severity of methemoglobinemia can be increased when Trifluridine is combined with Phenol. |
| Gemcitabine | The risk or severity of methemoglobinemia can be increased when Gemcitabine is combined with Phenol. |
| Teniposide | The risk or severity of methemoglobinemia can be increased when Teniposide is combined with Phenol. |
| Epirubicin | The risk or severity of methemoglobinemia can be increased when Epirubicin is combined with Phenol. |
| Lenalidomide | The risk or severity of methemoglobinemia can be increased when Lenalidomide is combined with Phenol. |
| Altretamine | The risk or severity of methemoglobinemia can be increased when Altretamine is combined with Phenol. |
| Flutamide | The risk or severity of methemoglobinemia can be increased when Flutamide is combined with Phenol. |
| Cisplatin | The risk or severity of methemoglobinemia can be increased when Cisplatin is combined with Phenol. |
| Alitretinoin | The risk or severity of methemoglobinemia can be increased when Alitretinoin is combined with Phenol. |
| Oxaliplatin | The risk or severity of methemoglobinemia can be increased when Oxaliplatin is combined with Phenol. |
| Erlotinib | The risk or severity of methemoglobinemia can be increased when Erlotinib is combined with Phenol. |
| Cyclophosphamide | The risk or severity of methemoglobinemia can be increased when Cyclophosphamide is combined with Phenol. |
| Toremifene | The risk or severity of methemoglobinemia can be increased when Toremifene is combined with Phenol. |
| Vincristine | The risk or severity of methemoglobinemia can be increased when Vincristine is combined with Phenol. |
| Fluorouracil | The risk or severity of methemoglobinemia can be increased when Fluorouracil is combined with Phenol. |
| Pentostatin | The risk or severity of methemoglobinemia can be increased when Pentostatin is combined with Phenol. |
| Methotrexate | The risk or severity of methemoglobinemia can be increased when Methotrexate is combined with Phenol. |
| Vinblastine | The risk or severity of methemoglobinemia can be increased when Vinblastine is combined with Phenol. |
| Medroxyprogesterone acetate | The risk or severity of methemoglobinemia can be increased when Medroxyprogesterone acetate is combined with Phenol. |
| Imatinib | The risk or severity of methemoglobinemia can be increased when Imatinib is combined with Phenol. |
| Clofarabine | The risk or severity of methemoglobinemia can be increased when Clofarabine is combined with Phenol. |
| Prednisone | The risk or severity of methemoglobinemia can be increased when Prednisone is combined with Phenol. |
| Pemetrexed | The risk or severity of methemoglobinemia can be increased when Pemetrexed is combined with Phenol. |