Flavin adenine dinucleotide

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) -

Volume Distribusi -

Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data

1. Avoid alcohol. Ingesting alcohol may reduce the absorption of FAD.

Interaksi Obat

0 Data

Tidak ada data.

Target Protein

Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2

Nitric oxide synthase 1 NOS1

Dihydropyrimidine dehydrogenase [NADP(+)] DPYD

Xanthine dehydrogenase/oxidase XDH

Glutathione reductase, mitochondrial GSR

NAD(P)H dehydrogenase [quinone] 1 NQO1

Amine oxidase [flavin-containing] A MAOA

Thioredoxin reductase 1, cytoplasmic TXNRD1

Amine oxidase [flavin-containing] B MAOB

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9

p-hydroxybenzoate hydroxylase pobA

Fumarate reductase flavoprotein subunit

ERO1-like protein beta ERO1B

NADPH-ferredoxin reductase FprA fprA

NADH-cytochrome b5 reductase 3 CYB5R3

Cholesterol oxidase choA

Thymidylate synthase ThyX thyX

Pyruvate oxidase pox5

Glutathione reductase gor

Monomeric sarcosine oxidase soxA

Trypanothione reductase TPR

Isovaleryl-CoA dehydrogenase, mitochondrial IVD

Cholesterol oxidase choB

D-lactate dehydrogenase dld

Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8

Apoptosis-inducing factor 1, mitochondrial AIFM1

UDP-galactopyranose mutase glf

Flavohemoprotein hmp

Glycine oxidase thiO

NADPH--cytochrome P450 reductase POR

Glutaryl-CoA dehydrogenase, mitochondrial GCDH

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM

D-amino-acid oxidase DAO

Bifunctional protein PutA putA

Deoxyribodipyrimidine photo-lyase phr

Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS

L-amino-acid oxidase IL4I1

2,4-dienoyl-CoA reductase [NADPH] fadH

2-oxopropyl-CoM reductase, carboxylating xecC

Fumarate reductase flavoprotein subunit fccA

Thioredoxin reductase trxB

5,10-methylenetetrahydrofolate reductase metF

Dimethylglycine oxidase dmg

NADH peroxidase npr

Ferredoxin--NADP reductase petH

Sulfite reductase [NADPH] flavoprotein alpha-component cysJ

Ferredoxin--NADP reductase fpr

Acyl-CoA dehydrogenase, short-chain specific

Ferredoxin reductase bphA4

Dihydrolipoyl dehydrogenase

Amine oxidase, flavin-containing protein

Deoxyribodipyrimidine photo-lyase phrB

Deoxyribodipyrimidine photo-lyase phr

L-aspartate oxidase nadB

Cryptochrome DASH cry

Dihydrolipoyl dehydrogenase, mitochondrial DLD

Fumarate reductase flavoprotein subunit ifcA

NADH-cytochrome b5 reductase 1 CYB5R1

Oxidoreductase

NADPH:adrenodoxin oxidoreductase, mitochondrial FDXR

Peroxisomal acyl-coenzyme A oxidase 1 ACOX1

UDP-N-acetylenolpyruvoylglucosamine reductase murB

FAD-linked sulfhydryl oxidase ALR GFER

UDP-N-acetylenolpyruvoylglucosamine reductase murB

Flavohemoprotein hmp

Phenol 2-hydroxylase component B pheA2

Methylenetetrahydrofolate reductase metF

Putidaredoxin reductase camA

NAD(P)H dehydrogenase (quinone) lpdA

UDP-galactopyranose mutase glf

4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase abfD

4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF

Alkyl hydroperoxide reductase subunit F ahpF

Dihydrolipoyl dehydrogenase m-6

Glutathione reductase GR2

Phenylacetone monooxygenase pamO

Benzoate 1,2-dioxygenase electron transfer component benC

Putative acyl-CoA dehydrogenase

FkbI fkbI

Dihydrolipoyl dehydrogenase lpdV

Dihydrolipoyl dehydrogenase lpd

Alkyl hydroperoxide reductase subunit F ahpF

Ferredoxin--NADP reductase petH

Ferredoxin--NADP reductase fpr

Mersacidin decarboxylase mrsD

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 7 • International brands: 2

Produk

BumP DHA

Capsule • - • Oral • US
BumP DHA

Capsule • - • Oral • US
EnBrace HR

Capsule, delayed release pellets • - • Oral • US
Enl

Capsule, liquid filled • - • Oral • US
EnLyte

Capsule, delayed release pellets • - • Oral • US
PaxLyte

Capsule • - • Oral • US
PramLyte

Kit • - • Oral • US • Generic • Approved

International Brands

Adeflavin
Flaziren

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.

Peringatan Keamanan

Deskripsi

Struktur Molekul 2D

Deskripsi metode visualisasi