Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Allopurinol | The risk or severity of adverse effects can be increased when Piretanide is combined with Allopurinol. |
| Canagliflozin | The risk or severity of hypotension can be increased when Canagliflozin is combined with Piretanide. |
| Cisplatin | The risk or severity of ototoxicity and nephrotoxicity can be increased when Piretanide is combined with Cisplatin. |
| Dofetilide | The risk or severity of QTc prolongation, torsade de pointes, hypokalemia, hypomagnesemia, and cardiac arrest can be increased when Piretanide is combined with Dofetilide. |
| Foscarnet | Piretanide may decrease the excretion rate of Foscarnet which could result in a higher serum level. |
| Ivabradine | The risk or severity of Cardiac Arrhythmia can be increased when Piretanide is combined with Ivabradine. |
| Lithium citrate | Piretanide may decrease the excretion rate of Lithium citrate which could result in a higher serum level. |
| Lithium carbonate | Piretanide may decrease the excretion rate of Lithium carbonate which could result in a higher serum level. |
| Lithium hydroxide | Piretanide may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level. |
| Nicotine | The risk or severity of adverse effects can be increased when Piretanide is combined with Nicotine. |
| Mecamylamine | The risk or severity of adverse effects can be increased when Piretanide is combined with Mecamylamine. |
| Pentolinium | The risk or severity of adverse effects can be increased when Piretanide is combined with Pentolinium. |
| Trimethaphan | The risk or severity of adverse effects can be increased when Piretanide is combined with Trimethaphan. |
| Hexamethonium | The risk or severity of adverse effects can be increased when Piretanide is combined with Hexamethonium. |
| Cyclopentamine | The risk or severity of adverse effects can be increased when Piretanide is combined with Cyclopentamine. |
| Probenecid | The risk or severity of adverse effects can be increased when Probenecid is combined with Piretanide. |
| Risperidone | The risk or severity of hypotension can be increased when Piretanide is combined with Risperidone. |
| Topiramate | The risk or severity of hypokalemia can be increased when Piretanide is combined with Topiramate. |
| Methotrexate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Methotrexate. |
| Digoxin | The risk or severity of adverse effects can be increased when Piretanide is combined with Digoxin. |
| Acetyldigitoxin | The risk or severity of adverse effects can be increased when Piretanide is combined with Acetyldigitoxin. |
| Deslanoside | The risk or severity of adverse effects can be increased when Piretanide is combined with Deslanoside. |
| Ouabain | The risk or severity of adverse effects can be increased when Piretanide is combined with Ouabain. |
| Digitoxin | The risk or severity of adverse effects can be increased when Piretanide is combined with Digitoxin. |
| Oleandrin | The risk or severity of adverse effects can be increased when Piretanide is combined with Oleandrin. |
| Cymarin | The risk or severity of adverse effects can be increased when Piretanide is combined with Cymarin. |
| Proscillaridin | The risk or severity of adverse effects can be increased when Piretanide is combined with Proscillaridin. |
| Metildigoxin | The risk or severity of adverse effects can be increased when Piretanide is combined with Metildigoxin. |
| Lanatoside C | The risk or severity of adverse effects can be increased when Piretanide is combined with Lanatoside C. |
| Gitoformate | The risk or severity of adverse effects can be increased when Piretanide is combined with Gitoformate. |
| Acetyldigoxin | The risk or severity of adverse effects can be increased when Piretanide is combined with Acetyldigoxin. |
| Peruvoside | The risk or severity of adverse effects can be increased when Piretanide is combined with Peruvoside. |
| Icosapent | The therapeutic efficacy of Piretanide can be decreased when used in combination with Icosapent. |
| Mesalazine | The risk or severity of adverse effects can be increased when Piretanide is combined with Mesalazine. |
| Nabumetone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Nabumetone. |
| Ketorolac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Ketorolac. |
| Tenoxicam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Tenoxicam. |
| Celecoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Celecoxib. |
| Tolmetin | The therapeutic efficacy of Piretanide can be decreased when used in combination with Tolmetin. |
| Rofecoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Rofecoxib. |
| Piroxicam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Piroxicam. |
| Fenoprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Fenoprofen. |
| Valdecoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Valdecoxib. |
| Diclofenac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Diclofenac. |
| Sulindac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Sulindac. |
| Flurbiprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Flurbiprofen. |
| Etodolac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Etodolac. |
| Mefenamic acid | The therapeutic efficacy of Piretanide can be decreased when used in combination with Mefenamic acid. |
| Naproxen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Naproxen. |
| Sulfasalazine | The therapeutic efficacy of Piretanide can be decreased when used in combination with Sulfasalazine. |
| Phenylbutazone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Phenylbutazone. |
| Carprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Carprofen. |
| Diflunisal | The therapeutic efficacy of Piretanide can be decreased when used in combination with Diflunisal. |
| Salicylic acid | The therapeutic efficacy of Piretanide can be decreased when used in combination with Salicylic acid. |
| Meclofenamic acid | The therapeutic efficacy of Piretanide can be decreased when used in combination with Meclofenamic acid. |
| Oxaprozin | The therapeutic efficacy of Piretanide can be decreased when used in combination with Oxaprozin. |
| Ketoprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Ketoprofen. |
| Balsalazide | The therapeutic efficacy of Piretanide can be decreased when used in combination with Balsalazide. |
| Ibuprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Ibuprofen. |
| Olsalazine | The risk or severity of adverse effects can be increased when Piretanide is combined with Olsalazine. |
| Lumiracoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Lumiracoxib. |
| Magnesium salicylate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Magnesium salicylate. |
| Salsalate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Salsalate. |
| Choline magnesium trisalicylate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Choline magnesium trisalicylate. |
| Antrafenine | The therapeutic efficacy of Piretanide can be decreased when used in combination with Antrafenine. |
| Aminophenazone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Aminophenazone. |
| Antipyrine | The therapeutic efficacy of Piretanide can be decreased when used in combination with Antipyrine. |
| Tiaprofenic acid | The therapeutic efficacy of Piretanide can be decreased when used in combination with Tiaprofenic acid. |
| Etoricoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Etoricoxib. |
| Taxifolin | The therapeutic efficacy of Piretanide can be decreased when used in combination with Taxifolin. |
| Oxyphenbutazone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Oxyphenbutazone. |
| Licofelone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Licofelone. |
| Nimesulide | The therapeutic efficacy of Piretanide can be decreased when used in combination with Nimesulide. |
| Benoxaprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Benoxaprofen. |
| Zomepirac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Zomepirac. |
| Cimicoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Cimicoxib. |
| Lornoxicam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Lornoxicam. |
| Aceclofenac | The therapeutic efficacy of Piretanide can be decreased when used in combination with Aceclofenac. |
| Zaltoprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Zaltoprofen. |
| Azapropazone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Azapropazone. |
| Parecoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Parecoxib. |
| Salicylamide | The therapeutic efficacy of Piretanide can be decreased when used in combination with Salicylamide. |
| Kebuzone | The therapeutic efficacy of Piretanide can be decreased when used in combination with Kebuzone. |
| Isoxicam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Isoxicam. |
| Indoprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Indoprofen. |
| Ibuproxam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Ibuproxam. |
| Floctafenine | The therapeutic efficacy of Piretanide can be decreased when used in combination with Floctafenine. |
| Fenbufen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Fenbufen. |
| Etofenamate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Etofenamate. |
| Epirizole | The therapeutic efficacy of Piretanide can be decreased when used in combination with Epirizole. |
| Benzydamine | The therapeutic efficacy of Piretanide can be decreased when used in combination with Benzydamine. |
| Dexibuprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Dexibuprofen. |
| Dexketoprofen | The therapeutic efficacy of Piretanide can be decreased when used in combination with Dexketoprofen. |
| Droxicam | The therapeutic efficacy of Piretanide can be decreased when used in combination with Droxicam. |
| Tolfenamic acid | The therapeutic efficacy of Piretanide can be decreased when used in combination with Tolfenamic acid. |
| Firocoxib | The therapeutic efficacy of Piretanide can be decreased when used in combination with Firocoxib. |
| Clonixin | The therapeutic efficacy of Piretanide can be decreased when used in combination with Clonixin. |
| Morniflumate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Morniflumate. |
| Propacetamol | The therapeutic efficacy of Piretanide can be decreased when used in combination with Propacetamol. |
| Talniflumate | The therapeutic efficacy of Piretanide can be decreased when used in combination with Talniflumate. |