A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pitolisant | The serum concentration of Pregnenolone can be decreased when it is combined with Pitolisant. |
| Metreleptin | The metabolism of Pregnenolone can be increased when combined with Metreleptin. |
| Cenobamate | The serum concentration of Pregnenolone can be decreased when it is combined with Cenobamate. |
| Ritonavir | The serum concentration of Pregnenolone can be increased when it is combined with Ritonavir. |
| Haloperidol | The serum concentration of Haloperidol can be increased when it is combined with Pregnenolone. |
| Tucatinib | The metabolism of Tucatinib can be decreased when combined with Pregnenolone. |
| Abametapir | The serum concentration of Pregnenolone can be increased when it is combined with Abametapir. |
| Satralizumab | The serum concentration of Pregnenolone can be decreased when it is combined with Satralizumab. |
| Sotorasib | The serum concentration of Pregnenolone can be decreased when it is combined with Sotorasib. |
| Cyclosporine | The metabolism of Pregnenolone can be decreased when combined with Cyclosporine. |
| Fluvoxamine | The metabolism of Pregnenolone can be decreased when combined with Fluvoxamine. |
| Fluconazole | The metabolism of Pregnenolone can be decreased when combined with Fluconazole. |
| Erythromycin | The serum concentration of Pregnenolone can be increased when it is combined with Erythromycin. |
| Ziprasidone | The metabolism of Pregnenolone can be decreased when combined with Ziprasidone. |
| Isradipine | The metabolism of Pregnenolone can be decreased when combined with Isradipine. |
| Diltiazem | The metabolism of Pregnenolone can be decreased when combined with Diltiazem. |
| Clozapine | The metabolism of Pregnenolone can be decreased when combined with Clozapine. |
| Ciprofloxacin | The metabolism of Pregnenolone can be decreased when combined with Ciprofloxacin. |
| Nicardipine | The metabolism of Pregnenolone can be decreased when combined with Nicardipine. |
| Verapamil | The metabolism of Pregnenolone can be decreased when combined with Verapamil. |
| Aprepitant | The metabolism of Pregnenolone can be decreased when combined with Aprepitant. |
| Isoniazid | The metabolism of Pregnenolone can be decreased when combined with Isoniazid. |
| Primaquine | The metabolism of Pregnenolone can be decreased when combined with Primaquine. |
| Miconazole | The metabolism of Pregnenolone can be decreased when combined with Miconazole. |
| Fusidic acid | The metabolism of Pregnenolone can be decreased when combined with Fusidic acid. |
| Zimelidine | The metabolism of Pregnenolone can be decreased when combined with Zimelidine. |
| Dronedarone | The metabolism of Pregnenolone can be decreased when combined with Dronedarone. |
| Milnacipran | The metabolism of Pregnenolone can be decreased when combined with Milnacipran. |
| Simeprevir | The metabolism of Pregnenolone can be decreased when combined with Simeprevir. |
| Isavuconazonium | The metabolism of Pregnenolone can be decreased when combined with Isavuconazonium. |
| Desvenlafaxine | The metabolism of Pregnenolone can be decreased when combined with Desvenlafaxine. |
| Nilvadipine | The metabolism of Pregnenolone can be decreased when combined with Nilvadipine. |
| Seproxetine | The metabolism of Pregnenolone can be decreased when combined with Seproxetine. |
| Linagliptin | The metabolism of Pregnenolone can be decreased when combined with Linagliptin. |
| Indalpine | The metabolism of Pregnenolone can be decreased when combined with Indalpine. |
| Netupitant | The metabolism of Pregnenolone can be decreased when combined with Netupitant. |
| Barnidipine | The metabolism of Pregnenolone can be decreased when combined with Barnidipine. |
| Benidipine | The metabolism of Pregnenolone can be decreased when combined with Benidipine. |
| Venetoclax | The metabolism of Pregnenolone can be decreased when combined with Venetoclax. |
| Isavuconazole | The metabolism of Pregnenolone can be decreased when combined with Isavuconazole. |
| Fosnetupitant | The metabolism of Pregnenolone can be decreased when combined with Fosnetupitant. |
| Berotralstat | The metabolism of Pregnenolone can be decreased when combined with Berotralstat. |
| Midostaurin | The metabolism of Pregnenolone can be decreased when combined with Midostaurin. |
| Voriconazole | The metabolism of Pregnenolone can be decreased when combined with Voriconazole. |
| Danazol | The metabolism of Pregnenolone can be decreased when combined with Danazol. |
| Nelfinavir | The metabolism of Pregnenolone can be decreased when combined with Nelfinavir. |
| Indinavir | The metabolism of Pregnenolone can be decreased when combined with Indinavir. |
| Terfenadine | The metabolism of Pregnenolone can be decreased when combined with Terfenadine. |
| Efavirenz | The metabolism of Pregnenolone can be decreased when combined with Efavirenz. |
| Ergotamine | The metabolism of Pregnenolone can be decreased when combined with Ergotamine. |
| Amprenavir | The metabolism of Pregnenolone can be decreased when combined with Amprenavir. |
| Delavirdine | The metabolism of Pregnenolone can be decreased when combined with Delavirdine. |
| Methimazole | The metabolism of Pregnenolone can be decreased when combined with Methimazole. |
| Conivaptan | The metabolism of Pregnenolone can be decreased when combined with Conivaptan. |
| Tipranavir | The metabolism of Pregnenolone can be decreased when combined with Tipranavir. |
| Telithromycin | The metabolism of Pregnenolone can be decreased when combined with Telithromycin. |
| Ketoconazole | The metabolism of Pregnenolone can be decreased when combined with Ketoconazole. |
| Atazanavir | The metabolism of Pregnenolone can be decreased when combined with Atazanavir. |
| Amiodarone | The metabolism of Pregnenolone can be decreased when combined with Amiodarone. |
| Nefazodone | The metabolism of Pregnenolone can be decreased when combined with Nefazodone. |
| Itraconazole | The metabolism of Pregnenolone can be decreased when combined with Itraconazole. |
| Clarithromycin | The metabolism of Pregnenolone can be decreased when combined with Clarithromycin. |
| Saquinavir | The metabolism of Pregnenolone can be decreased when combined with Saquinavir. |
| Posaconazole | The metabolism of Pregnenolone can be decreased when combined with Posaconazole. |
| Darunavir | The metabolism of Pregnenolone can be decreased when combined with Darunavir. |
| Lopinavir | The metabolism of Pregnenolone can be decreased when combined with Lopinavir. |
| Ditiocarb | The metabolism of Pregnenolone can be decreased when combined with Ditiocarb. |
| Nilotinib | The metabolism of Pregnenolone can be decreased when combined with Nilotinib. |
| Telaprevir | The metabolism of Pregnenolone can be decreased when combined with Telaprevir. |
| Lonafarnib | The metabolism of Pregnenolone can be decreased when combined with Lonafarnib. |
| Boceprevir | The metabolism of Pregnenolone can be decreased when combined with Boceprevir. |
| Elvitegravir | The metabolism of Pregnenolone can be decreased when combined with Elvitegravir. |
| Stiripentol | The metabolism of Pregnenolone can be decreased when combined with Stiripentol. |
| Ribociclib | The metabolism of Pregnenolone can be decreased when combined with Ribociclib. |
| Danoprevir | The metabolism of Pregnenolone can be decreased when combined with Danoprevir. |
| Troleandomycin | The metabolism of Pregnenolone can be decreased when combined with Troleandomycin. |
| Phenytoin | The metabolism of Pregnenolone can be increased when combined with Phenytoin. |
| Pentobarbital | The metabolism of Pregnenolone can be increased when combined with Pentobarbital. |
| Carbamazepine | The metabolism of Pregnenolone can be increased when combined with Carbamazepine. |
| Mitotane | The metabolism of Pregnenolone can be increased when combined with Mitotane. |
| Primidone | The metabolism of Pregnenolone can be increased when combined with Primidone. |
| Rifampin | The metabolism of Pregnenolone can be increased when combined with Rifampicin. |
| Phenobarbital | The metabolism of Pregnenolone can be increased when combined with Phenobarbital. |
| Dexamethasone | The metabolism of Pregnenolone can be increased when combined with Dexamethasone. |
| Fosphenytoin | The metabolism of Pregnenolone can be increased when combined with Fosphenytoin. |
| St. John's Wort | The metabolism of Pregnenolone can be increased when combined with St. John's Wort. |
| Enzalutamide | The serum concentration of Pregnenolone can be decreased when it is combined with Enzalutamide. |
| Lumacaftor | The metabolism of Pregnenolone can be increased when combined with Lumacaftor. |
| Apalutamide | The serum concentration of Pregnenolone can be decreased when it is combined with Apalutamide. |
| Rifapentine | The metabolism of Pregnenolone can be increased when combined with Rifapentine. |
| Curcumin | The metabolism of Pregnenolone can be decreased when combined with Curcumin. |
| Somatrogon | The metabolism of Pregnenolone can be increased when combined with Somatrogon. |
| Levoketoconazole | The metabolism of Pregnenolone can be decreased when combined with Levoketoconazole. |
| Mavacamten | The serum concentration of Pregnenolone can be decreased when it is combined with Mavacamten. |
| Viloxazine | The metabolism of Pregnenolone can be decreased when combined with Viloxazine. |
| Ivosidenib | The metabolism of Pregnenolone can be increased when combined with Ivosidenib. |
| Dabrafenib | The serum concentration of Pregnenolone can be decreased when it is combined with Dabrafenib. |
| Telotristat ethyl | The serum concentration of Pregnenolone can be decreased when it is combined with Telotristat ethyl. |
| Avanafil | The serum concentration of Avanafil can be increased when it is combined with Pregnenolone. |
| Omaveloxolone | The serum concentration of Pregnenolone can be decreased when it is combined with Omaveloxolone. |