Pyroquilon

DB02756

small molecule experimental

Deskripsi

Pyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene reductase active site.

Struktur Molekul 2D

Berat 173.2111

Wujud solid

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) -

Volume Distribusi -

Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

14 Data

Dicoumarol	The therapeutic efficacy of Dicoumarol can be increased when used in combination with Pyroquilon.
Phenindione	The therapeutic efficacy of Phenindione can be increased when used in combination with Pyroquilon.
Warfarin	The therapeutic efficacy of Warfarin can be increased when used in combination with Pyroquilon.
Phenprocoumon	The therapeutic efficacy of Phenprocoumon can be increased when used in combination with Pyroquilon.
Acenocoumarol	The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Pyroquilon.
4-hydroxycoumarin	The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Pyroquilon.
Coumarin	The therapeutic efficacy of Coumarin can be increased when used in combination with Pyroquilon.
(R)-warfarin	The therapeutic efficacy of (R)-warfarin can be increased when used in combination with Pyroquilon.
Ethyl biscoumacetate	The therapeutic efficacy of Ethyl biscoumacetate can be increased when used in combination with Pyroquilon.
Fluindione	The therapeutic efficacy of Fluindione can be increased when used in combination with Pyroquilon.
Clorindione	The therapeutic efficacy of Clorindione can be increased when used in combination with Pyroquilon.
Diphenadione	The therapeutic efficacy of Diphenadione can be increased when used in combination with Pyroquilon.
Tioclomarol	The therapeutic efficacy of Tioclomarol can be increased when used in combination with Pyroquilon.
(S)-Warfarin	The therapeutic efficacy of (S)-Warfarin can be increased when used in combination with Pyroquilon.

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 4

International Brands

Coratop
Fongoren
Fongorene
Lilolidone

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.