Cholic Acid

DB02659

small molecule approved

Deskripsi

A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. PubChem
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome).

Struktur Molekul 2D

Berat 408.5714
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Take separate from antacids. Take at least 1 hour before or 4-6 hours after aluminum-containing antacids.
  • 2. Take with food.

Interaksi Obat

468 Data
Lepirudin The risk or severity of bleeding and bruising can be increased when Lepirudin is combined with Cholic Acid.
Bivalirudin The risk or severity of bleeding and bruising can be increased when Bivalirudin is combined with Cholic Acid.
Alteplase The risk or severity of bleeding and bruising can be increased when Alteplase is combined with Cholic Acid.
Urokinase The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Cholic Acid.
Reteplase The risk or severity of bleeding and bruising can be increased when Reteplase is combined with Cholic Acid.
Anistreplase The risk or severity of bleeding and bruising can be increased when Anistreplase is combined with Cholic Acid.
Tenecteplase The risk or severity of bleeding and bruising can be increased when Tenecteplase is combined with Cholic Acid.
Drotrecogin alfa The risk or severity of bleeding and bruising can be increased when Drotrecogin alfa is combined with Cholic Acid.
Streptokinase The risk or severity of bleeding and bruising can be increased when Streptokinase is combined with Cholic Acid.
Dicoumarol The risk or severity of bleeding and bruising can be increased when Dicoumarol is combined with Cholic Acid.
Argatroban The risk or severity of bleeding and bruising can be increased when Argatroban is combined with Cholic Acid.
Ardeparin The risk or severity of bleeding and bruising can be increased when Ardeparin is combined with Cholic Acid.
Phenindione The risk or severity of bleeding and bruising can be increased when Phenindione is combined with Cholic Acid.
Fondaparinux The risk or severity of bleeding and bruising can be increased when Fondaparinux is combined with Cholic Acid.
Warfarin The risk or severity of bleeding and bruising can be increased when Warfarin is combined with Cholic Acid.
Pentosan polysulfate The risk or severity of bleeding and bruising can be increased when Pentosan polysulfate is combined with Cholic Acid.
Phenprocoumon The risk or severity of bleeding and bruising can be increased when Phenprocoumon is combined with Cholic Acid.
Heparin The risk or severity of bleeding and bruising can be increased when Heparin is combined with Cholic Acid.
Enoxaparin The risk or severity of bleeding and bruising can be increased when Enoxaparin is combined with Cholic Acid.
Acenocoumarol The risk or severity of bleeding and bruising can be increased when Acenocoumarol is combined with Cholic Acid.
4-hydroxycoumarin The risk or severity of bleeding and bruising can be increased when 4-hydroxycoumarin is combined with Cholic Acid.
Coumarin The risk or severity of bleeding and bruising can be increased when Coumarin is combined with Cholic Acid.
Ximelagatran The risk or severity of bleeding and bruising can be increased when Ximelagatran is combined with Cholic Acid.
Desmoteplase The risk or severity of bleeding and bruising can be increased when Desmoteplase is combined with Cholic Acid.
Ancrod The risk or severity of bleeding and bruising can be increased when Ancrod is combined with Cholic Acid.
Rivaroxaban The risk or severity of bleeding and bruising can be increased when Rivaroxaban is combined with Cholic Acid.
Sulodexide The risk or severity of bleeding and bruising can be increased when Sulodexide is combined with Cholic Acid.
Semuloparin The risk or severity of bleeding and bruising can be increased when Semuloparin is combined with Cholic Acid.
Idraparinux The risk or severity of bleeding and bruising can be increased when Idraparinux is combined with Cholic Acid.
Astaxanthin The risk or severity of bleeding and bruising can be increased when Astaxanthin is combined with Cholic Acid.
Apixaban The risk or severity of bleeding and bruising can be increased when Apixaban is combined with Cholic Acid.
Otamixaban The risk or severity of bleeding and bruising can be increased when Otamixaban is combined with Cholic Acid.
Amediplase The risk or severity of bleeding and bruising can be increased when Amediplase is combined with Cholic Acid.
Danaparoid The risk or severity of bleeding and bruising can be increased when Danaparoid is combined with Cholic Acid.
Dalteparin The risk or severity of bleeding and bruising can be increased when Dalteparin is combined with Cholic Acid.
Tinzaparin The risk or severity of bleeding and bruising can be increased when Tinzaparin is combined with Cholic Acid.
(R)-warfarin The risk or severity of bleeding and bruising can be increased when (R)-warfarin is combined with Cholic Acid.
Ethyl biscoumacetate The risk or severity of bleeding and bruising can be increased when Ethyl biscoumacetate is combined with Cholic Acid.
Nadroparin The risk or severity of bleeding and bruising can be increased when Nadroparin is combined with Cholic Acid.
Ditazole The risk or severity of bleeding and bruising can be increased when Ditazole is combined with Cholic Acid.
Edoxaban The risk or severity of bleeding and bruising can be increased when Edoxaban is combined with Cholic Acid.
Sodium citrate The risk or severity of bleeding and bruising can be increased when Sodium citrate is combined with Cholic Acid.
Dextran The risk or severity of bleeding and bruising can be increased when Dextran is combined with Cholic Acid.
Bemiparin The risk or severity of bleeding and bruising can be increased when Bemiparin is combined with Cholic Acid.
Parnaparin The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Cholic Acid.
Desirudin The risk or severity of bleeding and bruising can be increased when Desirudin is combined with Cholic Acid.
Antithrombin Alfa The risk or severity of bleeding and bruising can be increased when Antithrombin Alfa is combined with Cholic Acid.
Protein C The risk or severity of bleeding and bruising can be increased when Protein C is combined with Cholic Acid.
Antithrombin III human The risk or severity of bleeding and bruising can be increased when Antithrombin III human is combined with Cholic Acid.
Letaxaban The risk or severity of bleeding and bruising can be increased when Letaxaban is combined with Cholic Acid.
Darexaban The risk or severity of bleeding and bruising can be increased when Darexaban is combined with Cholic Acid.
Betrixaban The risk or severity of bleeding and bruising can be increased when Betrixaban is combined with Cholic Acid.
Nafamostat The risk or severity of bleeding and bruising can be increased when Nafamostat is combined with Cholic Acid.
Monteplase The risk or severity of bleeding and bruising can be increased when Monteplase is combined with Cholic Acid.
Gabexate The risk or severity of bleeding and bruising can be increased when Gabexate is combined with Cholic Acid.
Fluindione The risk or severity of bleeding and bruising can be increased when Fluindione is combined with Cholic Acid.
Protein S human The risk or severity of bleeding and bruising can be increased when Protein S human is combined with Cholic Acid.
Brinase The risk or severity of bleeding and bruising can be increased when Brinase is combined with Cholic Acid.
Clorindione The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Cholic Acid.
Diphenadione The risk or severity of bleeding and bruising can be increased when Diphenadione is combined with Cholic Acid.
Tioclomarol The risk or severity of bleeding and bruising can be increased when Tioclomarol is combined with Cholic Acid.
Melagatran The risk or severity of bleeding and bruising can be increased when Melagatran is combined with Cholic Acid.
Saruplase The risk or severity of bleeding and bruising can be increased when Saruplase is combined with Cholic Acid.
(S)-Warfarin The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Cholic Acid.
Tocopherylquinone The risk or severity of bleeding and bruising can be increased when Tocopherylquinone is combined with Cholic Acid.
Dabigatran The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Cholic Acid.
Dabigatran etexilate The risk or severity of bleeding and bruising can be increased when Dabigatran etexilate is combined with Cholic Acid.
Troxerutin The risk or severity of bleeding and bruising can be increased when Troxerutin is combined with Cholic Acid.
Edetic acid The risk or severity of bleeding and bruising can be increased when Edetic acid is combined with Cholic Acid.
Reviparin The risk or severity of bleeding and bruising can be increased when Reviparin is combined with Cholic Acid.
Dermatan sulfate The risk or severity of bleeding and bruising can be increased when Dermatan sulfate is combined with Cholic Acid.
SR-123781A The risk or severity of bleeding and bruising can be increased when SR-123781A is combined with Cholic Acid.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Cholic Acid.
Eptifibatide The risk or severity of adverse effects can be increased when Eptifibatide is combined with Cholic Acid.
Ticlopidine The risk or severity of adverse effects can be increased when Ticlopidine is combined with Cholic Acid.
Anagrelide The risk or severity of adverse effects can be increased when Anagrelide is combined with Cholic Acid.
Clopidogrel The risk or severity of adverse effects can be increased when Clopidogrel is combined with Cholic Acid.
Tirofiban The risk or severity of adverse effects can be increased when Tirofiban is combined with Cholic Acid.
Pentoxifylline The risk or severity of adverse effects can be increased when Pentoxifylline is combined with Cholic Acid.
Acetylsalicylic acid The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Cholic Acid.
Dipyridamole The risk or severity of adverse effects can be increased when Dipyridamole is combined with Cholic Acid.
Sulfinpyrazone The risk or severity of adverse effects can be increased when Sulfinpyrazone is combined with Cholic Acid.
Cilostazol The risk or severity of adverse effects can be increased when Cilostazol is combined with Cholic Acid.
Ridogrel The risk or severity of adverse effects can be increased when Ridogrel is combined with Cholic Acid.
Epoprostenol The risk or severity of adverse effects can be increased when Epoprostenol is combined with Cholic Acid.
Resveratrol The risk or severity of adverse effects can be increased when Resveratrol is combined with Cholic Acid.
Nimesulide The risk or severity of adverse effects can be increased when Nimesulide is combined with Cholic Acid.
Tesmilifene The risk or severity of adverse effects can be increased when Tesmilifene is combined with Cholic Acid.
Defibrotide The risk or severity of adverse effects can be increased when Defibrotide is combined with Cholic Acid.
Beraprost The risk or severity of adverse effects can be increased when Beraprost is combined with Cholic Acid.
Ibudilast The risk or severity of adverse effects can be increased when Ibudilast is combined with Cholic Acid.
Andrographolide The risk or severity of adverse effects can be increased when Andrographolide is combined with Cholic Acid.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Cholic Acid.
Prasugrel The risk or severity of adverse effects can be increased when Prasugrel is combined with Cholic Acid.
Cangrelor The risk or severity of adverse effects can be increased when Cangrelor is combined with Cholic Acid.
Tranilast The risk or severity of adverse effects can be increased when Tranilast is combined with Cholic Acid.
Triflusal The risk or severity of adverse effects can be increased when Triflusal is combined with Cholic Acid.
Ticagrelor The risk or severity of adverse effects can be increased when Ticagrelor is combined with Cholic Acid.
Icosapent ethyl The risk or severity of adverse effects can be increased when Icosapent ethyl is combined with Cholic Acid.
Vorapaxar The risk or severity of adverse effects can be increased when Vorapaxar is combined with Cholic Acid.

Target Protein

Phospholipase A2 PLA2G1B
Ferrochelatase, mitochondrial FECH
Liver carboxylesterase 1 CES1
Alcohol dehydrogenase 1C ADH1C
Estrogen-related receptor gamma ESRRG
Gastrotropin FABP6
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1
Cytochrome c oxidase subunit 1 MT-CO1
Cytochrome c oxidase subunit 2 MT-CO2
Cytochrome c oxidase subunit 3 MT-CO3
Cytochrome c oxidase subunit 5A, mitochondrial COX5A
Cytochrome c oxidase subunit 5B, mitochondrial COX5B
Cytochrome c oxidase subunit 6C COX6C
Cytochrome c oxidase subunit 7B, mitochondrial COX7B
Cytochrome c oxidase subunit 7C, mitochondrial COX7C
Cytochrome c oxidase subunit 8A, mitochondrial COX8A
Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2
Cytochrome c oxidase subunit 6B1 COX6B1
Cytochrome c oxidase subunit 7A1, mitochondrial COX7A1
Choloylglycine hydrolase cbh
Bile acid receptor NR1H4
G-protein coupled bile acid receptor 1 GPBAR1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 10 • International brands: 0
Produk
  • Cholbam
    Capsule • 50 mg/1 • Oral • US • Approved
  • Cholbam
    Capsule • 250 mg/1 • Oral • US • Approved
  • Kolbam
    Capsule • 50 mg • Oral • EU
  • Kolbam
    Capsule • 250 mg • Oral • EU
  • Orphacol
    Capsule • 50 mg • Oral • EU • Approved
  • Orphacol
    Capsule • 50 mg • Oral • EU • Approved
  • Orphacol
    Capsule • 50 mg • Oral • EU • Approved
  • Orphacol
    Capsule • 250 mg • Oral • EU • Approved
Menampilkan 8 dari 10 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul