Peldesine

DB02568

small molecule investigational

Deskripsi

Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.

Struktur Molekul 2D

Berat 241.2486
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

605 Data
Deferasirox The serum concentration of Peldesine can be increased when it is combined with Deferasirox.
Peginterferon alfa-2b The serum concentration of Peldesine can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Peldesine can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Peldesine can be decreased when it is combined with Teriflunomide.
Regadenoson Peldesine may decrease effectiveness of Regadenoson as a diagnostic agent.
Adalimumab The serum concentration of Peldesine can be decreased when it is combined with Adalimumab.
Adenosine The therapeutic efficacy of Adenosine can be decreased when used in combination with Peldesine.
Allopurinol The serum concentration of Peldesine can be increased when it is combined with Allopurinol.
Carbamazepine The serum concentration of Peldesine can be decreased when it is combined with Carbamazepine.
Cimetidine The metabolism of Peldesine can be decreased when combined with Cimetidine.
Disulfiram The serum concentration of Peldesine can be increased when it is combined with Disulfiram.
Febuxostat The serum concentration of the active metabolites of Peldesine can be increased when Peldesine is used in combination with Febuxostat.
Fluvoxamine The metabolism of Peldesine can be decreased when combined with Fluvoxamine.
Formoterol The risk or severity of hypokalemia can be increased when Peldesine is combined with Formoterol.
Indacaterol The risk or severity of adverse effects can be increased when Peldesine is combined with Indacaterol.
Isoniazid The serum concentration of Peldesine can be increased when it is combined with Isoniazid.
Lithium citrate The serum concentration of Lithium citrate can be decreased when it is combined with Peldesine.
Lithium carbonate The serum concentration of Lithium carbonate can be decreased when it is combined with Peldesine.
Lithium hydroxide The serum concentration of Lithium hydroxide can be decreased when it is combined with Peldesine.
Mexiletine The metabolism of Peldesine can be decreased when combined with Mexiletine.
Olodaterol Peldesine may increase the hyperkalemic activities of Olodaterol.
Pancuronium The therapeutic efficacy of Pancuronium can be decreased when used in combination with Peldesine.
Pentoxifylline The serum concentration of Peldesine can be increased when it is combined with Pentoxifylline.
Phenytoin The serum concentration of Peldesine can be decreased when it is combined with Phenytoin.
Fosphenytoin The serum concentration of Peldesine can be decreased when it is combined with Fosphenytoin.
Propafenone The serum concentration of Peldesine can be increased when it is combined with Propafenone.
Quinine The serum concentration of Peldesine can be increased when it is combined with Quinine.
Quinidine The serum concentration of Peldesine can be increased when it is combined with Quinidine.
Riociguat Peldesine may increase the hypotensive activities of Riociguat.
Thiabendazole The metabolism of Peldesine can be decreased when combined with Thiabendazole.
Ticlopidine The metabolism of Peldesine can be decreased when combined with Ticlopidine.
Zafirlukast The serum concentration of Zafirlukast can be decreased when it is combined with Peldesine.
Probenecid The serum concentration of Peldesine can be increased when it is combined with Probenecid.
Abiraterone The serum concentration of Peldesine can be increased when it is combined with Abiraterone.
Isoprenaline The serum concentration of Peldesine can be decreased when it is combined with Isoprenaline.
Cyproterone acetate The metabolism of Peldesine can be increased when combined with Cyproterone acetate.
Amphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Peldesine.
Phentermine The risk or severity of adverse effects can be increased when Phentermine is combined with Peldesine.
Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Peldesine.
Norepinephrine The risk or severity of adverse effects can be increased when Norepinephrine is combined with Peldesine.
Phenylephrine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Peldesine.
Phenylpropanolamine The risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Peldesine.
Labetalol The risk or severity of adverse effects can be increased when Labetalol is combined with Peldesine.
Metaraminol The risk or severity of adverse effects can be increased when Metaraminol is combined with Peldesine.
Epinephrine The risk or severity of adverse effects can be increased when Epinephrine is combined with Peldesine.
Methoxamine The risk or severity of adverse effects can be increased when Methoxamine is combined with Peldesine.
Orciprenaline The risk or severity of adverse effects can be increased when Orciprenaline is combined with Peldesine.
Phenmetrazine The risk or severity of adverse effects can be increased when Phenmetrazine is combined with Peldesine.
Dobutamine The risk or severity of adverse effects can be increased when Dobutamine is combined with Peldesine.
Pseudoephedrine The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Peldesine.
Benzphetamine The risk or severity of adverse effects can be increased when Benzphetamine is combined with Peldesine.
Ritodrine The risk or severity of adverse effects can be increased when Ritodrine is combined with Peldesine.
Terbutaline The risk or severity of adverse effects can be increased when Terbutaline is combined with Peldesine.
Oxymetazoline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Peldesine.
Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Peldesine.
Dopamine The risk or severity of adverse effects can be increased when Dopamine is combined with Peldesine.
Acebutolol The risk or severity of adverse effects can be increased when Acebutolol is combined with Peldesine.
Lisdexamfetamine The risk or severity of adverse effects can be increased when Lisdexamfetamine is combined with Peldesine.
Fenoterol The risk or severity of adverse effects can be increased when Fenoterol is combined with Peldesine.
Ephedrine The risk or severity of adverse effects can be increased when Ephedrine is combined with Peldesine.
Mephentermine The risk or severity of adverse effects can be increased when Mephentermine is combined with Peldesine.
Procaterol The risk or severity of adverse effects can be increased when Procaterol is combined with Peldesine.
Clenbuterol The risk or severity of adverse effects can be increased when Clenbuterol is combined with Peldesine.
MMDA The risk or severity of adverse effects can be increased when MMDA is combined with Peldesine.
Midomafetamine The risk or severity of adverse effects can be increased when Midomafetamine is combined with Peldesine.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Peldesine.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Peldesine.
Tenamfetamine The risk or severity of adverse effects can be increased when Tenamfetamine is combined with Peldesine.
Chlorphentermine The risk or severity of adverse effects can be increased when Chlorphentermine is combined with Peldesine.
Methylenedioxyethamphetamine The risk or severity of adverse effects can be increased when Methylenedioxyethamphetamine is combined with Peldesine.
Dextroamphetamine The risk or severity of adverse effects can be increased when Dextroamphetamine is combined with Peldesine.
Metamfetamine The risk or severity of adverse effects can be increased when Metamfetamine is combined with Peldesine.
Celiprolol The risk or severity of adverse effects can be increased when Celiprolol is combined with Peldesine.
Nylidrin The risk or severity of adverse effects can be increased when Nylidrin is combined with Peldesine.
Tetryzoline The risk or severity of adverse effects can be increased when Tetryzoline is combined with Peldesine.
Tyramine The risk or severity of adverse effects can be increased when Tyramine is combined with Peldesine.
Isoxsuprine The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Peldesine.
Etilefrine The risk or severity of adverse effects can be increased when Etilefrine is combined with Peldesine.
Synephrine The risk or severity of adverse effects can be increased when Synephrine is combined with Peldesine.
Hydroxyamphetamine The risk or severity of adverse effects can be increased when Hydroxyamphetamine is combined with Peldesine.
Iofetamine I-123 The risk or severity of adverse effects can be increased when Iofetamine I-123 is combined with Peldesine.
Racepinephrine The risk or severity of adverse effects can be increased when Racepinephrine is combined with Peldesine.
Ritobegron The risk or severity of adverse effects can be increased when Ritobegron is combined with Peldesine.
Bucindolol The risk or severity of adverse effects can be increased when Bucindolol is combined with Peldesine.
Tramazoline The risk or severity of adverse effects can be increased when Tramazoline is combined with Peldesine.
Mephedrone The risk or severity of adverse effects can be increased when Mephedrone is combined with Peldesine.
Fenozolone The risk or severity of adverse effects can be increased when Fenozolone is combined with Peldesine.
Methoxyphenamine The risk or severity of adverse effects can be increased when Methoxyphenamine is combined with Peldesine.
Tretoquinol The risk or severity of adverse effects can be increased when Tretoquinol is combined with Peldesine.
Gepefrine The risk or severity of adverse effects can be increased when Gepefrine is combined with Peldesine.
Epanolol The risk or severity of adverse effects can be increased when Epanolol is combined with Peldesine.
Prenalterol The risk or severity of adverse effects can be increased when Prenalterol is combined with Peldesine.
Mefenorex The risk or severity of adverse effects can be increased when Mefenorex is combined with Peldesine.
2,5-Dimethoxy-4-ethylthioamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Peldesine.
Esmolol The risk or severity of adverse effects can be increased when Esmolol is combined with Peldesine.
Betaxolol The risk or severity of adverse effects can be increased when Betaxolol is combined with Peldesine.
Metoprolol The risk or severity of adverse effects can be increased when Metoprolol is combined with Peldesine.
Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Peldesine.
Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Peldesine.
Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Peldesine.

Target Protein

Purine nucleoside phosphorylase PNP

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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