Cyclic adenosine monophosphate

DB02527

small molecule experimental

Deskripsi

Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).

Struktur Molekul 2D

Berat 329.2059
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

137 Data
Aspartame The excretion of Cyclic adenosine monophosphate can be decreased when combined with Aspartame.
Pravastatin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Pravastatin.
Pantoprazole The excretion of Cyclic adenosine monophosphate can be decreased when combined with Pantoprazole.
Cefotiam The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefotiam.
Liothyronine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Liothyronine.
Conjugated estrogens The excretion of Cyclic adenosine monophosphate can be decreased when combined with Conjugated estrogens.
Valproic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Valproic acid.
Indomethacin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Indomethacin.
Aminohippuric acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Aminohippuric acid.
Lansoprazole The excretion of Cyclic adenosine monophosphate can be decreased when combined with Lansoprazole.
Cefalotin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefalotin.
Tenoxicam The excretion of Cyclic adenosine monophosphate can be decreased when combined with Tenoxicam.
Cefotaxime The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefotaxime.
Zidovudine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Zidovudine.
Cimetidine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cimetidine.
Guanidine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Guanidine.
Piroxicam The excretion of Cyclic adenosine monophosphate can be decreased when combined with Piroxicam.
Methotrexate The excretion of Cyclic adenosine monophosphate can be decreased when combined with Methotrexate.
Cephalexin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cephalexin.
Enalapril The excretion of Cyclic adenosine monophosphate can be decreased when combined with Enalapril.
Diclofenac The excretion of Cyclic adenosine monophosphate can be decreased when combined with Diclofenac.
Oxytetracycline The excretion of Cyclic adenosine monophosphate can be decreased when combined with Oxytetracycline.
Leucovorin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Leucovorin.
Furosemide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Furosemide.
Esomeprazole The excretion of Cyclic adenosine monophosphate can be decreased when combined with Esomeprazole.
Tetracycline The excretion of Cyclic adenosine monophosphate can be decreased when combined with Tetracycline.
Acyclovir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Acyclovir.
Phenylbutazone The excretion of Cyclic adenosine monophosphate can be decreased when combined with Phenylbutazone.
Cefaclor The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefaclor.
Bumetanide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Bumetanide.
Quinidine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Quinidine.
Dinoprostone The excretion of Cyclic adenosine monophosphate can be decreased when combined with Dinoprostone.
Famotidine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Famotidine.
Salicylic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Salicylic acid.
Acetylsalicylic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Acetylsalicylic acid.
Ganciclovir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ganciclovir.
Ketoprofen The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ketoprofen.
Minocycline The excretion of Cyclic adenosine monophosphate can be decreased when combined with Minocycline.
Probenecid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Probenecid.
Mercaptopurine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Mercaptopurine.
Ibuprofen The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ibuprofen.
Novobiocin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Novobiocin.
Benzylpenicillin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Benzylpenicillin.
Melatonin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Melatonin.
Ouabain The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ouabain.
Rosuvastatin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Rosuvastatin.
Cefadroxil The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefadroxil.
Ceftriaxone The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ceftriaxone.
Cefamandole The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefamandole.
Cefazolin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefazolin.
Cefoperazone The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefoperazone.
Ceftizoxime The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ceftizoxime.
Cefacetrile The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefacetrile.
Ceftibuten The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ceftibuten.
Liotrix The excretion of Cyclic adenosine monophosphate can be decreased when combined with Liotrix.
Cilastatin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cilastatin.
Tazobactam The excretion of Cyclic adenosine monophosphate can be decreased when combined with Tazobactam.
trans-2-hydroxycinnamic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with trans-2-hydroxycinnamic acid.
Topiroxostat The excretion of Cyclic adenosine monophosphate can be decreased when combined with Topiroxostat.
Cholic Acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cholic Acid.
Glutaric Acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Glutaric Acid.
Benzoic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Benzoic acid.
Taurocholic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Taurocholic acid.
Caprylic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Caprylic acid.
Ataluren The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ataluren.
Teriflunomide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Teriflunomide.
Dabrafenib The excretion of Cyclic adenosine monophosphate can be decreased when combined with Dabrafenib.
Dolutegravir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Dolutegravir.
Cefaloridine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefaloridine.
Lenvatinib The excretion of Cyclic adenosine monophosphate can be decreased when combined with Lenvatinib.
Cabotegravir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cabotegravir.
Apalutamide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Apalutamide.
Pradigastat The excretion of Cyclic adenosine monophosphate can be decreased when combined with Pradigastat.
Enasidenib The excretion of Cyclic adenosine monophosphate can be decreased when combined with Enasidenib.
Gemfibrozil The excretion of Cyclic adenosine monophosphate can be decreased when combined with Gemfibrozil.
Dronedarone The excretion of Cyclic adenosine monophosphate can be decreased when combined with Dronedarone.
Favipiravir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Favipiravir.
Tafamidis The excretion of Cyclic adenosine monophosphate can be decreased when combined with Tafamidis.
Linezolid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Linezolid.
Testosterone The excretion of Cyclic adenosine monophosphate can be increased when combined with Testosterone.
Methyltestosterone The excretion of Cyclic adenosine monophosphate can be increased when combined with Methyltestosterone.
Testosterone cypionate The excretion of Cyclic adenosine monophosphate can be increased when combined with Testosterone cypionate.
Testosterone enanthate The excretion of Cyclic adenosine monophosphate can be increased when combined with Testosterone enanthate.
Cyclosporine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cyclosporine.
Riboflavin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Riboflavin.
Folic acid The excretion of Cyclic adenosine monophosphate can be decreased when combined with Folic acid.
Ethoxzolamide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Ethoxzolamide.
Codeine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Codeine.
Piperacillin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Piperacillin.
Cidofovir The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cidofovir.
Trifluridine The excretion of Cyclic adenosine monophosphate can be decreased when combined with Trifluridine.
Chloramphenicol The excretion of Cyclic adenosine monophosphate can be decreased when combined with Chloramphenicol.
Tolmetin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Tolmetin.
Caspofungin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Caspofungin.
Foscarnet The excretion of Cyclic adenosine monophosphate can be decreased when combined with Foscarnet.
Carbenicillin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Carbenicillin.
Sulindac The excretion of Cyclic adenosine monophosphate can be decreased when combined with Sulindac.
Cyclothiazide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cyclothiazide.
Nafcillin The excretion of Cyclic adenosine monophosphate can be decreased when combined with Nafcillin.
Chlorpropamide The excretion of Cyclic adenosine monophosphate can be decreased when combined with Chlorpropamide.

Target Protein

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2
cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A
cAMP-dependent protein kinase type II-beta regulatory subunit PRKAR2B
cAMP-activated global transcriptional regulator CRP crp
Adenylate cyclase cyaB2
Cyclic nucleotide-gated potassium channel mll3241

Referensi & Sumber

Synthesis reference: Shigehiro Kataoka, Ayako Nasu, Nobuyuki Yamaji, Motohiko Kato, "Process for preparation of N.sup.6 -substituted 3',5'-cyclic adenosine monophosphate and salt thereof." U.S. Patent US4751293, issued July, 1984.

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Sekuens Gen/Protein (FASTA)

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