Geldanamycin

DB02424

small molecule experimental investigational

Deskripsi

Struktur Molekul 2D

Berat 560.6359
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

66 Data
Acetaminophen The serum concentration of Acetaminophen can be increased when it is combined with Geldanamycin.
Propacetamol The serum concentration of Propacetamol can be increased when it is combined with Geldanamycin.
Salmon calcitonin The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Geldanamycin.
Thyrotropin alfa The therapeutic efficacy of Thyrotropin alfa can be decreased when used in combination with Geldanamycin.
Follitropin The therapeutic efficacy of Follitropin can be decreased when used in combination with Geldanamycin.
Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Geldanamycin.
Carbimazole The therapeutic efficacy of Carbimazole can be decreased when used in combination with Geldanamycin.
Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Geldanamycin.
Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Geldanamycin.
Methimazole The therapeutic efficacy of Methimazole can be decreased when used in combination with Geldanamycin.
Liotrix The therapeutic efficacy of Liotrix can be decreased when used in combination with Geldanamycin.
3,5-Diiodotyrosine The therapeutic efficacy of 3,5-Diiodotyrosine can be decreased when used in combination with Geldanamycin.
Tiratricol The therapeutic efficacy of Tiratricol can be decreased when used in combination with Geldanamycin.
Parathyroid hormone The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Geldanamycin.
Teriparatide The therapeutic efficacy of Teriparatide can be decreased when used in combination with Geldanamycin.
Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Geldanamycin.
Dibromotyrosine The therapeutic efficacy of Dibromotyrosine can be decreased when used in combination with Geldanamycin.
Thyroid, porcine The therapeutic efficacy of Thyroid, porcine can be decreased when used in combination with Geldanamycin.
Potassium perchlorate The therapeutic efficacy of Potassium perchlorate can be decreased when used in combination with Geldanamycin.
Protirelin The therapeutic efficacy of Protirelin can be decreased when used in combination with Geldanamycin.
3,5-diiodothyropropionic acid The therapeutic efficacy of 3,5-diiodothyropropionic acid can be decreased when used in combination with Geldanamycin.
Methylthiouracil The therapeutic efficacy of Methylthiouracil can be decreased when used in combination with Geldanamycin.
Elcatonin The therapeutic efficacy of Elcatonin can be decreased when used in combination with Geldanamycin.
Benzylthiouracil The therapeutic efficacy of Benzylthiouracil can be decreased when used in combination with Geldanamycin.
Thyrotropin The therapeutic efficacy of Thyrotropin can be decreased when used in combination with Geldanamycin.
Darbepoetin alfa The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Geldanamycin.
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Geldanamycin.
Peginesatide The risk or severity of Thrombosis can be increased when Peginesatide is combined with Geldanamycin.
Methoxy polyethylene glycol-epoetin beta The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Geldanamycin.
Lidocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Quinisocaine.
Voriconazole The serum concentration of Geldanamycin can be increased when it is combined with Voriconazole.
Nelarabine The risk or severity of adverse effects can be increased when Nelarabine is combined with Geldanamycin.
Ambroxol The risk or severity of methemoglobinemia can be increased when Geldanamycin is combined with Ambroxol.
Etrasimod The risk or severity of immunosuppression can be increased when Geldanamycin is combined with Etrasimod.
Palopegteriparatide The therapeutic efficacy of Palopegteriparatide can be decreased when used in combination with Geldanamycin.

Target Protein

Heat shock protein HSP 90-alpha HSP90AA1
Endoplasmin HSP90B1
Heat shock protein HSP 90-beta HSP90AB1

Referensi & Sumber

Synthesis reference: Richard Hutchinson, "Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof." U.S. Patent US20040077058, issued April 22, 2004.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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