Guanine

DB02377

small molecule experimental

Deskripsi

Struktur Molekul 2D

Berat 151.1261
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

369 Data
Regadenoson Guanine may decrease effectiveness of Regadenoson as a diagnostic agent.
Adalimumab The serum concentration of Guanine can be decreased when it is combined with Adalimumab.
Adenosine The therapeutic efficacy of Adenosine can be decreased when used in combination with Guanine.
Allopurinol The serum concentration of Guanine can be increased when it is combined with Allopurinol.
Carbamazepine The serum concentration of Guanine can be decreased when it is combined with Carbamazepine.
Cimetidine The metabolism of Guanine can be decreased when combined with Cimetidine.
Disulfiram The serum concentration of Guanine can be increased when it is combined with Disulfiram.
Febuxostat The serum concentration of the active metabolites of Guanine can be increased when Guanine is used in combination with Febuxostat.
Fluvoxamine The metabolism of Guanine can be decreased when combined with Fluvoxamine.
Formoterol The risk or severity of hypokalemia can be increased when Guanine is combined with Formoterol.
Indacaterol The risk or severity of adverse effects can be increased when Guanine is combined with Indacaterol.
Isoniazid The serum concentration of Guanine can be increased when it is combined with Isoniazid.
Lithium citrate The serum concentration of Lithium citrate can be decreased when it is combined with Guanine.
Lithium carbonate The serum concentration of Lithium carbonate can be decreased when it is combined with Guanine.
Lithium hydroxide The serum concentration of Lithium hydroxide can be decreased when it is combined with Guanine.
Mexiletine The metabolism of Guanine can be decreased when combined with Mexiletine.
Olodaterol Guanine may increase the hyperkalemic activities of Olodaterol.
Pancuronium The therapeutic efficacy of Pancuronium can be decreased when used in combination with Guanine.
Pentoxifylline The serum concentration of Guanine can be increased when it is combined with Pentoxifylline.
Phenytoin The serum concentration of Guanine can be decreased when it is combined with Phenytoin.
Fosphenytoin The serum concentration of Guanine can be decreased when it is combined with Fosphenytoin.
Propafenone The serum concentration of Guanine can be increased when it is combined with Propafenone.
Quinine The serum concentration of Guanine can be increased when it is combined with Quinine.
Quinidine The serum concentration of Guanine can be increased when it is combined with Quinidine.
Riociguat Guanine may increase the hypotensive activities of Riociguat.
Thiabendazole The metabolism of Guanine can be decreased when combined with Thiabendazole.
Ticlopidine The metabolism of Guanine can be decreased when combined with Ticlopidine.
Zafirlukast The serum concentration of Zafirlukast can be decreased when it is combined with Guanine.
Probenecid The serum concentration of Guanine can be increased when it is combined with Probenecid.
Isoprenaline The serum concentration of Guanine can be decreased when it is combined with Isoprenaline.
Amphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Guanine.
Phentermine The risk or severity of adverse effects can be increased when Phentermine is combined with Guanine.
Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Guanine.
Norepinephrine The risk or severity of adverse effects can be increased when Norepinephrine is combined with Guanine.
Phenylephrine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Guanine.
Phenylpropanolamine The risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Guanine.
Labetalol The risk or severity of adverse effects can be increased when Labetalol is combined with Guanine.
Metaraminol The risk or severity of adverse effects can be increased when Metaraminol is combined with Guanine.
Epinephrine The risk or severity of adverse effects can be increased when Epinephrine is combined with Guanine.
Methoxamine The risk or severity of adverse effects can be increased when Methoxamine is combined with Guanine.
Orciprenaline The risk or severity of adverse effects can be increased when Orciprenaline is combined with Guanine.
Phenmetrazine The risk or severity of adverse effects can be increased when Phenmetrazine is combined with Guanine.
Dobutamine The risk or severity of adverse effects can be increased when Dobutamine is combined with Guanine.
Pseudoephedrine The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Guanine.
Benzphetamine The risk or severity of adverse effects can be increased when Benzphetamine is combined with Guanine.
Ritodrine The risk or severity of adverse effects can be increased when Ritodrine is combined with Guanine.
Terbutaline The risk or severity of adverse effects can be increased when Terbutaline is combined with Guanine.
Oxymetazoline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Guanine.
Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Guanine.
Dopamine The risk or severity of adverse effects can be increased when Dopamine is combined with Guanine.
Acebutolol The risk or severity of adverse effects can be increased when Acebutolol is combined with Guanine.
Lisdexamfetamine The risk or severity of adverse effects can be increased when Lisdexamfetamine is combined with Guanine.
Fenoterol The risk or severity of adverse effects can be increased when Fenoterol is combined with Guanine.
Ephedrine The risk or severity of adverse effects can be increased when Ephedrine is combined with Guanine.
Mephentermine The risk or severity of adverse effects can be increased when Mephentermine is combined with Guanine.
Procaterol The risk or severity of adverse effects can be increased when Procaterol is combined with Guanine.
Clenbuterol The risk or severity of adverse effects can be increased when Clenbuterol is combined with Guanine.
MMDA The risk or severity of adverse effects can be increased when MMDA is combined with Guanine.
Midomafetamine The risk or severity of adverse effects can be increased when Midomafetamine is combined with Guanine.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Guanine.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Guanine.
Tenamfetamine The risk or severity of adverse effects can be increased when Tenamfetamine is combined with Guanine.
Chlorphentermine The risk or severity of adverse effects can be increased when Chlorphentermine is combined with Guanine.
Methylenedioxyethamphetamine The risk or severity of adverse effects can be increased when Methylenedioxyethamphetamine is combined with Guanine.
Dextroamphetamine The risk or severity of adverse effects can be increased when Dextroamphetamine is combined with Guanine.
Metamfetamine The risk or severity of adverse effects can be increased when Metamfetamine is combined with Guanine.
Celiprolol The risk or severity of adverse effects can be increased when Celiprolol is combined with Guanine.
Nylidrin The risk or severity of adverse effects can be increased when Nylidrin is combined with Guanine.
Tetryzoline The risk or severity of adverse effects can be increased when Tetryzoline is combined with Guanine.
Tyramine The risk or severity of adverse effects can be increased when Tyramine is combined with Guanine.
Isoxsuprine The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Guanine.
Etilefrine The risk or severity of adverse effects can be increased when Etilefrine is combined with Guanine.
Synephrine The risk or severity of adverse effects can be increased when Synephrine is combined with Guanine.
Hydroxyamphetamine The risk or severity of adverse effects can be increased when Hydroxyamphetamine is combined with Guanine.
Iofetamine I-123 The risk or severity of adverse effects can be increased when Iofetamine I-123 is combined with Guanine.
Racepinephrine The risk or severity of adverse effects can be increased when Racepinephrine is combined with Guanine.
Ritobegron The risk or severity of adverse effects can be increased when Ritobegron is combined with Guanine.
Bucindolol The risk or severity of adverse effects can be increased when Bucindolol is combined with Guanine.
Tramazoline The risk or severity of adverse effects can be increased when Tramazoline is combined with Guanine.
Mephedrone The risk or severity of adverse effects can be increased when Mephedrone is combined with Guanine.
Fenozolone The risk or severity of adverse effects can be increased when Fenozolone is combined with Guanine.
Methoxyphenamine The risk or severity of adverse effects can be increased when Methoxyphenamine is combined with Guanine.
Tretoquinol The risk or severity of adverse effects can be increased when Tretoquinol is combined with Guanine.
Gepefrine The risk or severity of adverse effects can be increased when Gepefrine is combined with Guanine.
Epanolol The risk or severity of adverse effects can be increased when Epanolol is combined with Guanine.
Prenalterol The risk or severity of adverse effects can be increased when Prenalterol is combined with Guanine.
Mefenorex The risk or severity of adverse effects can be increased when Mefenorex is combined with Guanine.
2,5-Dimethoxy-4-ethylthioamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Guanine.
Esmolol The risk or severity of adverse effects can be increased when Esmolol is combined with Guanine.
Betaxolol The risk or severity of adverse effects can be increased when Betaxolol is combined with Guanine.
Metoprolol The risk or severity of adverse effects can be increased when Metoprolol is combined with Guanine.
Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Guanine.
Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Guanine.
Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Guanine.
Propranolol The risk or severity of adverse effects can be increased when Propranolol is combined with Guanine.
Bisoprolol The risk or severity of adverse effects can be increased when Bisoprolol is combined with Guanine.
Alprenolol The risk or severity of adverse effects can be increased when Alprenolol is combined with Guanine.
Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Guanine.
Carvedilol The risk or severity of adverse effects can be increased when Carvedilol is combined with Guanine.
Bevantolol The risk or severity of adverse effects can be increased when Bevantolol is combined with Guanine.

Target Protein

GTP cyclohydrolase 1 GCH1
Purine nucleoside phosphorylase PNP
Purine nucleoside phosphorylase 2 xapA
Xanthine phosphoribosyltransferase gpt
Purine nucleoside phosphorylase

Referensi & Sumber

Synthesis reference: Takeo Suzuki, Toshihide Nakanishi, "(2'-Amino-2'-deoxypentofuranosyl) guanine and process for producing same." U.S. Patent US3987030, issued April, 1966.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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