A phosphodiesterase inhibitor with antidepressant properties.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Hydrocodone | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Magnesium sulfate | The therapeutic efficacy of Rolipram can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Rolipram may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Mirtazapine | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Orphenadrine | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Pramipexole | Rolipram may increase the sedative activities of Pramipexole. |
| Ropinirole | Rolipram may increase the sedative activities of Ropinirole. |
| Rotigotine | Rolipram may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Rolipram. |
| Sodium oxybate | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Thalidomide | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Rolipram. |
| Dicoumarol | The risk or severity of adverse effects can be increased when Rolipram is combined with Dicoumarol. |
| Phenindione | The risk or severity of adverse effects can be increased when Rolipram is combined with Phenindione. |
| Warfarin | The risk or severity of adverse effects can be increased when Rolipram is combined with Warfarin. |
| Phenprocoumon | The risk or severity of adverse effects can be increased when Rolipram is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of adverse effects can be increased when Rolipram is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of adverse effects can be increased when Rolipram is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of adverse effects can be increased when Rolipram is combined with Coumarin. |
| (R)-warfarin | The risk or severity of adverse effects can be increased when Rolipram is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of adverse effects can be increased when Rolipram is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of adverse effects can be increased when Rolipram is combined with Fluindione. |
| Clorindione | The risk or severity of adverse effects can be increased when Rolipram is combined with Clorindione. |
| Diphenadione | The risk or severity of adverse effects can be increased when Rolipram is combined with Diphenadione. |
| Tioclomarol | The risk or severity of adverse effects can be increased when Rolipram is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of adverse effects can be increased when Rolipram is combined with (S)-Warfarin. |
| Riociguat | Rolipram may increase the hypotensive activities of Riociguat. |
| Ethanol | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Rolipram may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Rolipram is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Rolipram is combined with Dapoxetine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Rolipram is combined with Seproxetine. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Rolipram is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Rolipram is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Rolipram is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Rolipram is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Rolipram is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Rolipram is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Rolipram is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Rolipram is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Rolipram is combined with Escitalopram. |
| Milnacipran | The risk or severity of adverse effects can be increased when Rolipram is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Rolipram is combined with Desvenlafaxine. |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Rolipram is combined with Levomilnacipran. |
| Indalpine | The risk or severity of adverse effects can be increased when Rolipram is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Rolipram is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Rolipram is combined with Alaproclate. |
| Cyproheptadine | The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Rolipram. |
| Propiomazine | The risk or severity of CNS depression can be increased when Propiomazine is combined with Rolipram. |
| Zopiclone | The risk or severity of adverse effects can be increased when Rolipram is combined with Zopiclone. |
| Botulinum toxin type B | The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Rolipram. |
| Botulinum toxin type A | The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Rolipram. |
| Baclofen | Baclofen may increase the central nervous system depressant (CNS depressant) activities of Rolipram. |
| Ethchlorvynol | The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Rolipram. |
| Succinylcholine | The risk or severity of CNS depression can be increased when Succinylcholine is combined with Rolipram. |
| Eletriptan | The risk or severity of CNS depression can be increased when Eletriptan is combined with Rolipram. |
| Enflurane | The risk or severity of CNS depression can be increased when Enflurane is combined with Rolipram. |
| Butabarbital | The risk or severity of CNS depression can be increased when Butabarbital is combined with Rolipram. |
| Butalbital | The risk or severity of CNS depression can be increased when Butalbital is combined with Rolipram. |
| Methysergide | The risk or severity of CNS depression can be increased when Methysergide is combined with Rolipram. |
| Cabergoline | The risk or severity of CNS depression can be increased when Cabergoline is combined with Rolipram. |
| Phenytoin | The risk or severity of CNS depression can be increased when Phenytoin is combined with Rolipram. |
| Topiramate | The risk or severity of CNS depression can be increased when Topiramate is combined with Rolipram. |
| Clemastine | The risk or severity of CNS depression can be increased when Clemastine is combined with Rolipram. |
| Etomidate | The risk or severity of CNS depression can be increased when Etomidate is combined with Rolipram. |
| Morphine | The risk or severity of CNS depression can be increased when Morphine is combined with Rolipram. |
| Talbutal | The risk or severity of CNS depression can be increased when Talbutal is combined with Rolipram. |
| Pentobarbital | The risk or severity of CNS depression can be increased when Pentobarbital is combined with Rolipram. |
| Zolmitriptan | The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Rolipram. |
| Codeine | The risk or severity of CNS depression can be increased when Codeine is combined with Rolipram. |
| Dihydroergotamine | The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Rolipram. |
| Tolcapone | The risk or severity of CNS depression can be increased when Tolcapone is combined with Rolipram. |
| Hydromorphone | The risk or severity of CNS depression can be increased when Hydromorphone is combined with Rolipram. |
| Cetirizine | The risk or severity of CNS depression can be increased when Cetirizine is combined with Rolipram. |
| Trimethadione | The risk or severity of CNS depression can be increased when Trimethadione is combined with Rolipram. |
| Chlorzoxazone | The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Rolipram. |
| Thiethylperazine | The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Rolipram. |
| Palonosetron | The risk or severity of CNS depression can be increased when Palonosetron is combined with Rolipram. |
| Dexbrompheniramine | The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Rolipram. |
| Metocurine iodide | The risk or severity of CNS depression can be increased when Metocurine iodide is combined with Rolipram. |
| Secobarbital | The risk or severity of CNS depression can be increased when Secobarbital is combined with Rolipram. |
| Methocarbamol | The risk or severity of CNS depression can be increased when Methocarbamol is combined with Rolipram. |
| Triprolidine | The risk or severity of CNS depression can be increased when Triprolidine is combined with Rolipram. |
| Meperidine | The risk or severity of CNS depression can be increased when Meperidine is combined with Rolipram. |
| Metharbital | The risk or severity of CNS depression can be increased when Metharbital is combined with Rolipram. |
| Quinine | The risk or severity of CNS depression can be increased when Quinine is combined with Rolipram. |