Pargyline

DB01626

small molecule approved

Deskripsi

Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.

Struktur Molekul 2D

Berat 159.2276
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid tyramine-containing foods and supplements. Foods that contain tyramine include yogurt, aged cheese, ripe bananas, wine, and sourdough bread.

Interaksi Obat

1349 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Pargyline.
Amifostine Pargyline may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Pargyline.
Obinutuzumab Pargyline may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Pargyline.
Rituximab Pargyline may increase the hypotensive activities of Rituximab.
Epicaptopril Epicaptopril may decrease the antihypertensive activities of Pargyline.
Siponimod Siponimod may decrease the antihypertensive activities of Pargyline.
Selpercatinib Selpercatinib may decrease the antihypertensive activities of Pargyline.
Naxitamab Naxitamab may decrease the antihypertensive activities of Pargyline.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Magnesium sulfate The therapeutic efficacy of Pargyline can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Pargyline may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Pargyline may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Orphenadrine Pargyline may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Pargyline may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Pargyline.
Pramipexole Pargyline may increase the sedative activities of Pramipexole.
Ropinirole Pargyline may increase the sedative activities of Ropinirole.
Rotigotine Pargyline may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Pargyline.
Sodium oxybate Pargyline may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Pargyline may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Thalidomide Pargyline may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Pargyline may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Desmopressin Desmopressin may decrease the antihypertensive activities of Pargyline.
Cyclosporine Cyclosporine may decrease the antihypertensive activities of Pargyline.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Pargyline.
Nicergoline Nicergoline may decrease the antihypertensive activities of Pargyline.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Pargyline.
Dutasteride Dutasteride may decrease the antihypertensive activities of Pargyline.
Propafenone Propafenone may decrease the antihypertensive activities of Pargyline.
Finasteride Finasteride may decrease the antihypertensive activities of Pargyline.
Ephedrine Ephedrine may decrease the antihypertensive activities of Pargyline.
1-benzylimidazole 1-benzylimidazole may decrease the antihypertensive activities of Pargyline.
Dronedarone Dronedarone may decrease the antihypertensive activities of Pargyline.
Amibegron Amibegron may decrease the antihypertensive activities of Pargyline.
Nylidrin Nylidrin may decrease the antihypertensive activities of Pargyline.
Solabegron Solabegron may decrease the antihypertensive activities of Pargyline.
Saralasin Saralasin may decrease the antihypertensive activities of Pargyline.
Tyramine Tyramine may decrease the antihypertensive activities of Pargyline.
Mirabegron Mirabegron may decrease the antihypertensive activities of Pargyline.
Adrafinil Adrafinil may decrease the antihypertensive activities of Pargyline.
Etilefrine Etilefrine may decrease the antihypertensive activities of Pargyline.
Synephrine Synephrine may decrease the antihypertensive activities of Pargyline.
Moxisylyte Moxisylyte may decrease the antihypertensive activities of Pargyline.
Dihydroergocornine Dihydroergocornine may decrease the antihypertensive activities of Pargyline.
DL-Methylephedrine DL-Methylephedrine may decrease the antihypertensive activities of Pargyline.
Amitraz Amitraz may decrease the antihypertensive activities of Pargyline.
Atipamezole Atipamezole may decrease the antihypertensive activities of Pargyline.
Ractopamine Ractopamine may decrease the antihypertensive activities of Pargyline.
Anisodamine Anisodamine may decrease the antihypertensive activities of Pargyline.
Tulobuterol Tulobuterol may decrease the antihypertensive activities of Pargyline.
Dopexamine Dopexamine may decrease the antihypertensive activities of Pargyline.
Idazoxan Idazoxan may decrease the antihypertensive activities of Pargyline.
Higenamine Higenamine may decrease the antihypertensive activities of Pargyline.
Reproterol Reproterol may decrease the antihypertensive activities of Pargyline.
Theodrenaline Theodrenaline may decrease the antihypertensive activities of Pargyline.
Tramazoline Tramazoline may decrease the antihypertensive activities of Pargyline.
Octopamine Octopamine may decrease the antihypertensive activities of Pargyline.
Fenozolone Fenozolone may decrease the antihypertensive activities of Pargyline.
Dihydroergocristine Dihydroergocristine may decrease the antihypertensive activities of Pargyline.
Norfenefrine Norfenefrine may decrease the antihypertensive activities of Pargyline.
Dihydroergocryptine Dihydroergocryptine may decrease the antihypertensive activities of Pargyline.
Oxyfedrine Oxyfedrine may decrease the antihypertensive activities of Pargyline.
Terguride Terguride may decrease the antihypertensive activities of Pargyline.
Xenon The risk or severity of adverse effects can be increased when Xenon is combined with Pargyline.
Rimiterol Rimiterol may decrease the antihypertensive activities of Pargyline.
Tretoquinol Tretoquinol may decrease the antihypertensive activities of Pargyline.
Prenalterol Prenalterol may decrease the antihypertensive activities of Pargyline.
Xamoterol Xamoterol may decrease the antihypertensive activities of Pargyline.
Mefenorex Mefenorex may decrease the antihypertensive activities of Pargyline.
Deoxyepinephrine Deoxyepinephrine may decrease the antihypertensive activities of Pargyline.
Quinoline Yellow WS Quinoline Yellow WS may decrease the antihypertensive activities of Pargyline.
Apraclonidine Pargyline may increase the alpha-adrenergic activities of Apraclonidine.
Atomoxetine The risk or severity of adverse effects can be increased when Pargyline is combined with Atomoxetine.
Betahistine The metabolism of Betahistine can be decreased when combined with Pargyline.
Bezafibrate Pargyline may increase the hepatotoxic activities of Bezafibrate.
Buprenorphine Pargyline may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Bupropion The risk or severity of adverse effects can be increased when Pargyline is combined with Bupropion.
Buspirone The risk or severity of hypertension can be increased when Pargyline is combined with Buspirone.
Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Pargyline.
Cyclobenzaprine Cyclobenzaprine may increase the serotonergic activities of Pargyline.
Cyproheptadine Pargyline may increase the anticholinergic activities of Cyproheptadine.
Dextromethorphan The risk or severity of serotonin syndrome can be increased when Pargyline is combined with Dextromethorphan.
Diethylpropion The risk or severity of adverse effects can be increased when Pargyline is combined with Diethylpropion.
Domperidone The risk or severity of QTc prolongation, torsade de pointes, and cardiotoxicity can be increased when Pargyline is combined with Domperidone.
Hydrocodone Pargyline may increase the serotonergic and central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydromorphone Pargyline may increase the serotonergic activities of Hydromorphone.
Isometheptene Pargyline may increase the sympathomimetic activities of Isometheptene.
Levonordefrin Pargyline may increase the hypertensive activities of Levonordefrin.
Lithium citrate The risk or severity of serotonin syndrome can be increased when Pargyline is combined with Lithium citrate.
Lithium carbonate The risk or severity of serotonin syndrome can be increased when Pargyline is combined with Lithium carbonate.
Lithium hydroxide The risk or severity of serotonin syndrome can be increased when Pargyline is combined with Lithium hydroxide.
Maprotiline The risk or severity of adverse effects can be increased when Pargyline is combined with Maprotiline.

Target Protein

Amine oxidase [flavin-containing] B MAOB
Amine oxidase [flavin-containing] A MAOA

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Eutonyl
  • Eutron

Sekuens Gen/Protein (FASTA)

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