Peringatan Keamanan

Symptoms of overdose include central nervous system depression, coma, difficulty swallowing, dizziness, drowsiness, head tilted to the side, low blood pressure, muscle twitching, rigid muscles, salivation, tremors, walking disturbances, and weakness.

Thiothixene

DB01623

small molecule approved

Deskripsi

A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

Struktur Molekul 2D

Berat 443.625
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 10-20 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid alcohol.

Interaksi Obat

1208 Data
Deferasirox The serum concentration of Thiothixene can be increased when it is combined with Deferasirox.
Peginterferon alfa-2b The serum concentration of Thiothixene can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Thiothixene can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Thiothixene can be decreased when it is combined with Teriflunomide.
Buprenorphine Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Hydrocodone Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Magnesium sulfate The therapeutic efficacy of Thiothixene can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Thiothixene may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Mirtazapine Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Orphenadrine Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Rotigotine Thiothixene may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Thiothixene.
Sodium oxybate Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Thalidomide Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Amisulpride Thiothixene may increase the antipsychotic activities of Amisulpride.
Methylphenidate The risk or severity of adverse effects can be increased when Thiothixene is combined with Methylphenidate.
Dexmethylphenidate The risk or severity of adverse effects can be increased when Thiothixene is combined with Dexmethylphenidate.
Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Thiothixene.
Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Thiothixene.
Sulpiride Thiothixene may increase the antipsychotic activities of Sulpiride.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Thiothixene.
Lithium citrate Lithium citrate may increase the neurotoxic activities of Thiothixene.
Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Thiothixene.
Mequitazine Thiothixene may increase the arrhythmogenic activities of Mequitazine.
Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Thiothixene.
Dicoumarol The risk or severity of adverse effects can be increased when Thiothixene is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Thiothixene is combined with Phenindione.
Phenprocoumon The risk or severity of adverse effects can be increased when Thiothixene is combined with Phenprocoumon.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Thiothixene is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Thiothixene is combined with Coumarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Thiothixene is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Thiothixene is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Thiothixene is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Thiothixene is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Thiothixene is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Thiothixene is combined with (S)-Warfarin.
Abiraterone The serum concentration of Thiothixene can be increased when it is combined with Abiraterone.
Cyproterone acetate The metabolism of Thiothixene can be increased when combined with Cyproterone acetate.
Ethanol Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Zimelidine The risk or severity of adverse effects can be increased when Thiothixene is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Thiothixene is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Thiothixene is combined with Seproxetine.
Citalopram The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Thiothixene is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Thiothixene is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Thiothixene is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Thiothixene is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Thiothixene is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Thiothixene is combined with Escitalopram.
Milnacipran The risk or severity of adverse effects can be increased when Thiothixene is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Thiothixene is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Thiothixene.
Indalpine The risk or severity of adverse effects can be increased when Thiothixene is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Thiothixene is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Thiothixene is combined with Alaproclate.
Carbidopa The therapeutic efficacy of Carbidopa can be decreased when used in combination with Thiothixene.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Thiothixene.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Thiothixene.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Thiothixene.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Thiothixene.
Apomorphine The therapeutic efficacy of Apomorphine can be decreased when used in combination with Thiothixene.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Thiothixene.
Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Thiothixene.
Memantine The therapeutic efficacy of Memantine can be decreased when used in combination with Thiothixene.
Pergolide The therapeutic efficacy of Pergolide can be decreased when used in combination with Thiothixene.
3,5-Dinitrocatechol The therapeutic efficacy of 3,5-Dinitrocatechol can be decreased when used in combination with Thiothixene.
Etilevodopa The therapeutic efficacy of Etilevodopa can be decreased when used in combination with Thiothixene.
Dexetimide The therapeutic efficacy of Dexetimide can be decreased when used in combination with Thiothixene.
Opicapone The therapeutic efficacy of Opicapone can be decreased when used in combination with Thiothixene.
Piribedil The therapeutic efficacy of Piribedil can be decreased when used in combination with Thiothixene.
Benserazide The therapeutic efficacy of Benserazide can be decreased when used in combination with Thiothixene.
Tropatepine The therapeutic efficacy of Tropatepine can be decreased when used in combination with Thiothixene.
Melevodopa The therapeutic efficacy of Melevodopa can be decreased when used in combination with Thiothixene.
Dihydroergocryptine The therapeutic efficacy of Dihydroergocryptine can be decreased when used in combination with Thiothixene.
Phenglutarimide The therapeutic efficacy of Phenglutarimide can be decreased when used in combination with Thiothixene.
Mazaticol The therapeutic efficacy of Mazaticol can be decreased when used in combination with Thiothixene.
Etybenzatropine The therapeutic efficacy of Etybenzatropine can be decreased when used in combination with Thiothixene.
Budipine The therapeutic efficacy of Budipine can be decreased when used in combination with Thiothixene.
Bornaprine The therapeutic efficacy of Bornaprine can be decreased when used in combination with Thiothixene.
Etanautine The therapeutic efficacy of Etanautine can be decreased when used in combination with Thiothixene.
Dexpramipexole The therapeutic efficacy of Dexpramipexole can be decreased when used in combination with Thiothixene.
Cabergoline The therapeutic efficacy of Cabergoline can be decreased when used in combination with Thiothixene.
Bromocriptine The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Thiothixene.
Rasagiline The therapeutic efficacy of Rasagiline can be decreased when used in combination with Thiothixene.
Tolcapone The therapeutic efficacy of Tolcapone can be decreased when used in combination with Thiothixene.
Entacapone The therapeutic efficacy of Entacapone can be decreased when used in combination with Thiothixene.
Levodopa The therapeutic efficacy of Levodopa can be decreased when used in combination with Thiothixene.

Target Protein

D(2) dopamine receptor DRD2
D(1A) dopamine receptor DRD1
5-hydroxytryptamine receptor 2A HTR2A

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 53 • International brands: 3
Produk
  • Navane
    Capsule • 1 mg/1 • Oral • US • Approved
  • Navane
    Capsule • 2 mg/1 • Oral • US • Approved
  • Navane
    Capsule • 5 mg/1 • Oral • US • Approved
  • Navane
    Capsule • 10 mg/1 • Oral • US • Approved
  • Navane
    Capsule • 20 mg/1 • Oral • US • Approved
  • Navane
    Solution, concentrate • 5 mg/1mL • Oral • US • Approved
  • Navane
    Capsule • 5 mg • Oral • Canada • Approved
  • Navane Cap 2mg
    Capsule • 2 mg • Oral • Canada • Approved
Menampilkan 8 dari 53 produk.
International Brands
  • Navan
  • Navaron
  • Orbinamon

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul