Peringatan Keamanan

Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

Phenindamine

DB01619

small molecule approved

Deskripsi

Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.
Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

Struktur Molekul 2D

Berat 261.3609
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid alcohol.
  • 2. Take with food. Food reduces irritation.

Interaksi Obat

39 Data
Benzylpenicilloyl polylysine Phenindamine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Phenindamine.
Hyaluronidase (ovine) The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Phenindamine.
Hyaluronidase (human recombinant) The therapeutic efficacy of Hyaluronidase (human recombinant) can be decreased when used in combination with Phenindamine.
Hyaluronidase The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Phenindamine.
Amphetamine Amphetamine may decrease the sedative activities of Phenindamine.
Phentermine Phentermine may decrease the sedative activities of Phenindamine.
Pseudoephedrine Pseudoephedrine may decrease the sedative activities of Phenindamine.
Benzphetamine Benzphetamine may decrease the sedative activities of Phenindamine.
Diethylpropion Diethylpropion may decrease the sedative activities of Phenindamine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Phenindamine.
Mephentermine Mephentermine may decrease the sedative activities of Phenindamine.
MMDA MMDA may decrease the sedative activities of Phenindamine.
Midomafetamine Midomafetamine may decrease the sedative activities of Phenindamine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Phenindamine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Phenindamine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Phenindamine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Phenindamine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Phenindamine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Phenindamine.
Metamfetamine Metamfetamine may decrease the sedative activities of Phenindamine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Phenindamine.
Ritobegron Ritobegron may decrease the sedative activities of Phenindamine.
Mephedrone Mephedrone may decrease the sedative activities of Phenindamine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Phenindamine.
Gepefrine Gepefrine may decrease the sedative activities of Phenindamine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Phenindamine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Phenindamine.
Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Phenindamine.
Norepinephrine The therapeutic efficacy of Norepinephrine can be increased when used in combination with Phenindamine.
Epinephrine The therapeutic efficacy of Epinephrine can be increased when used in combination with Phenindamine.
Droxidopa The therapeutic efficacy of Droxidopa can be increased when used in combination with Phenindamine.
Levonordefrin The therapeutic efficacy of Levonordefrin can be increased when used in combination with Phenindamine.
Protokylol The therapeutic efficacy of Protokylol can be increased when used in combination with Phenindamine.
Racepinephrine The therapeutic efficacy of Racepinephrine can be increased when used in combination with Phenindamine.
Theodrenaline The therapeutic efficacy of Theodrenaline can be increased when used in combination with Phenindamine.
Deoxyepinephrine The therapeutic efficacy of Deoxyepinephrine can be increased when used in combination with Phenindamine.
Ephedrine The therapeutic efficacy of Ephedrine can be increased when used in combination with Phenindamine.
Hyoscyamine Phenindamine may increase the anticholinergic activities of Hyoscyamine.

Target Protein

Histamine H1 receptor HRH1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Nolahist
  • Thephorin

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul