An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of clozapine. (From AMA Drug Evaluations Annual, 1994, p283)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Molindone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Hydrocodone | Molindone may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Magnesium sulfate | The therapeutic efficacy of Molindone can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Molindone may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Molindone may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Mirtazapine | Molindone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Orphenadrine | Molindone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Molindone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Rotigotine | Molindone may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Molindone. |
| Sodium oxybate | Molindone may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Molindone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Thalidomide | Molindone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Molindone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Amisulpride | Molindone may increase the antipsychotic activities of Amisulpride. |
| Methylphenidate | The risk or severity of adverse effects can be increased when Molindone is combined with Methylphenidate. |
| Dexmethylphenidate | The risk or severity of adverse effects can be increased when Molindone is combined with Dexmethylphenidate. |
| Metoclopramide | The risk or severity of adverse effects can be increased when Metoclopramide is combined with Molindone. |
| Quinagolide | The therapeutic efficacy of Quinagolide can be decreased when used in combination with Molindone. |
| Sulpiride | Molindone may increase the antipsychotic activities of Sulpiride. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Molindone. |
| Lithium citrate | Lithium citrate may increase the neurotoxic activities of Molindone. |
| Lithium hydroxide | Lithium hydroxide may increase the neurotoxic activities of Molindone. |
| Mequitazine | Molindone may increase the arrhythmogenic activities of Mequitazine. |
| Dicoumarol | The risk or severity of adverse effects can be increased when Molindone is combined with Dicoumarol. |
| Phenindione | The risk or severity of adverse effects can be increased when Molindone is combined with Phenindione. |
| Warfarin | The risk or severity of adverse effects can be increased when Molindone is combined with Warfarin. |
| Phenprocoumon | The risk or severity of adverse effects can be increased when Molindone is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of adverse effects can be increased when Molindone is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of adverse effects can be increased when Molindone is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of adverse effects can be increased when Molindone is combined with Coumarin. |
| (R)-warfarin | The risk or severity of adverse effects can be increased when Molindone is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of adverse effects can be increased when Molindone is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of adverse effects can be increased when Molindone is combined with Fluindione. |
| Clorindione | The risk or severity of adverse effects can be increased when Molindone is combined with Clorindione. |
| Diphenadione | The risk or severity of adverse effects can be increased when Molindone is combined with Diphenadione. |
| Tioclomarol | The risk or severity of adverse effects can be increased when Molindone is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of adverse effects can be increased when Molindone is combined with (S)-Warfarin. |
| Ethanol | Molindone may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Molindone may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Molindone. |
| Zimelidine | The risk or severity of adverse effects can be increased when Molindone is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Molindone is combined with Dapoxetine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Molindone is combined with Seproxetine. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Molindone is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Molindone is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Molindone is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Molindone is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Molindone is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Molindone is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Molindone is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Molindone is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Molindone is combined with Escitalopram. |
| Milnacipran | The risk or severity of adverse effects can be increased when Molindone is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Molindone is combined with Desvenlafaxine. |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Molindone. |
| Indalpine | The risk or severity of adverse effects can be increased when Molindone is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Molindone is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Molindone is combined with Alaproclate. |
| Carbidopa | The therapeutic efficacy of Carbidopa can be decreased when used in combination with Molindone. |
| Metixene | The therapeutic efficacy of Metixene can be decreased when used in combination with Molindone. |
| Trihexyphenidyl | The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Molindone. |
| Procyclidine | The therapeutic efficacy of Procyclidine can be decreased when used in combination with Molindone. |
| Profenamine | The therapeutic efficacy of Profenamine can be decreased when used in combination with Molindone. |
| Lisuride | The therapeutic efficacy of Lisuride can be decreased when used in combination with Molindone. |
| Apomorphine | The therapeutic efficacy of Apomorphine can be decreased when used in combination with Molindone. |
| Biperiden | The therapeutic efficacy of Biperiden can be decreased when used in combination with Molindone. |
| Amantadine | The therapeutic efficacy of Amantadine can be decreased when used in combination with Molindone. |
| Memantine | The therapeutic efficacy of Memantine can be decreased when used in combination with Molindone. |
| Pergolide | The therapeutic efficacy of Pergolide can be decreased when used in combination with Molindone. |
| 3,5-Dinitrocatechol | The therapeutic efficacy of 3,5-Dinitrocatechol can be decreased when used in combination with Molindone. |
| Etilevodopa | The therapeutic efficacy of Etilevodopa can be decreased when used in combination with Molindone. |
| Safinamide | The therapeutic efficacy of Safinamide can be decreased when used in combination with Molindone. |
| Dexetimide | The therapeutic efficacy of Dexetimide can be decreased when used in combination with Molindone. |
| Opicapone | The therapeutic efficacy of Opicapone can be decreased when used in combination with Molindone. |
| Piribedil | The therapeutic efficacy of Piribedil can be decreased when used in combination with Molindone. |
| Benserazide | The therapeutic efficacy of Benserazide can be decreased when used in combination with Molindone. |
| Tropatepine | The therapeutic efficacy of Tropatepine can be decreased when used in combination with Molindone. |
| Melevodopa | The therapeutic efficacy of Melevodopa can be decreased when used in combination with Molindone. |
| Dihydroergocryptine | The therapeutic efficacy of Dihydroergocryptine can be decreased when used in combination with Molindone. |
| Phenglutarimide | The therapeutic efficacy of Phenglutarimide can be decreased when used in combination with Molindone. |
| Mazaticol | The therapeutic efficacy of Mazaticol can be decreased when used in combination with Molindone. |
| Etybenzatropine | The therapeutic efficacy of Etybenzatropine can be decreased when used in combination with Molindone. |
| Budipine | The therapeutic efficacy of Budipine can be decreased when used in combination with Molindone. |
| Bornaprine | The therapeutic efficacy of Bornaprine can be decreased when used in combination with Molindone. |
| Etanautine | The therapeutic efficacy of Etanautine can be decreased when used in combination with Molindone. |
| Dexpramipexole | The therapeutic efficacy of Dexpramipexole can be decreased when used in combination with Molindone. |
| Cabergoline | The therapeutic efficacy of Cabergoline can be decreased when used in combination with Molindone. |
| Bromocriptine | The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Molindone. |
| Rasagiline | The therapeutic efficacy of Rasagiline can be decreased when used in combination with Molindone. |
| Tolcapone | The therapeutic efficacy of Tolcapone can be decreased when used in combination with Molindone. |
| Entacapone | The therapeutic efficacy of Entacapone can be decreased when used in combination with Molindone. |