Aceprometazine

DB01615

small molecule experimental

Deskripsi

Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.

Struktur Molekul 2D

Berat 326.456
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed following oral administration.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1084 Data
Ivabradine Ivabradine may increase the QTc-prolonging activities of Aceprometazine.
Buprenorphine Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Hydrocodone Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Magnesium sulfate The therapeutic efficacy of Aceprometazine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Mirtazapine Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Orphenadrine Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Rotigotine Aceprometazine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Aceprometazine.
Sodium oxybate Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Thalidomide Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Amisulpride Aceprometazine may increase the antipsychotic activities of Amisulpride.
Methylphenidate The risk or severity of adverse effects can be increased when Aceprometazine is combined with Methylphenidate.
Dexmethylphenidate The risk or severity of adverse effects can be increased when Aceprometazine is combined with Dexmethylphenidate.
Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Aceprometazine.
Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Aceprometazine.
Sulpiride Aceprometazine may increase the antipsychotic activities of Sulpiride.
Benzylpenicilloyl polylysine Aceprometazine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Aceprometazine.
Hyaluronidase (ovine) The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Aceprometazine.
Hyaluronidase (human recombinant) The therapeutic efficacy of Hyaluronidase (human recombinant) can be decreased when used in combination with Aceprometazine.
Hyaluronidase The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Aceprometazine.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Aceprometazine.
Lithium citrate Lithium citrate may increase the neurotoxic activities of Aceprometazine.
Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Aceprometazine.
Mequitazine Aceprometazine may increase the arrhythmogenic activities of Mequitazine.
Thiopental The risk or severity of adverse effects can be increased when Aceprometazine is combined with Thiopental.
Metyrosine The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Aceprometazine.
Ethanol Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Aceprometazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
Zimelidine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Fluvoxamine.
Duloxetine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Aceprometazine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Aceprometazine is combined with Nefazodone.
Milnacipran The risk or severity of adverse effects can be increased when Aceprometazine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Aceprometazine.
Indalpine The risk or severity of adverse effects can be increased when Aceprometazine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Aceprometazine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Aceprometazine is combined with Alaproclate.
Amphetamine Amphetamine may decrease the sedative activities of Aceprometazine.
Phentermine Phentermine may decrease the sedative activities of Aceprometazine.
Pseudoephedrine Pseudoephedrine may decrease the sedative activities of Aceprometazine.
Benzphetamine Benzphetamine may decrease the sedative activities of Aceprometazine.
Diethylpropion Diethylpropion may decrease the sedative activities of Aceprometazine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Aceprometazine.
Mephentermine Mephentermine may decrease the sedative activities of Aceprometazine.
MMDA MMDA may decrease the sedative activities of Aceprometazine.
Midomafetamine Midomafetamine may decrease the sedative activities of Aceprometazine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Aceprometazine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Aceprometazine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Aceprometazine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Aceprometazine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Aceprometazine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Aceprometazine.
Metamfetamine Metamfetamine may decrease the sedative activities of Aceprometazine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Aceprometazine.
Ritobegron Ritobegron may decrease the sedative activities of Aceprometazine.
Mephedrone Mephedrone may decrease the sedative activities of Aceprometazine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Aceprometazine.
Gepefrine Gepefrine may decrease the sedative activities of Aceprometazine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Aceprometazine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Aceprometazine.
Esmolol The serum concentration of Esmolol can be increased when it is combined with Aceprometazine.
Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Aceprometazine.
Metoprolol The serum concentration of Metoprolol can be increased when it is combined with Aceprometazine.
Atenolol The serum concentration of Atenolol can be increased when it is combined with Aceprometazine.
Timolol The serum concentration of Timolol can be increased when it is combined with Aceprometazine.
Propranolol The serum concentration of Propranolol can be increased when it is combined with Aceprometazine.
Labetalol The serum concentration of Labetalol can be increased when it is combined with Aceprometazine.
Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Aceprometazine.
Alprenolol The serum concentration of Alprenolol can be increased when it is combined with Aceprometazine.
Pindolol The serum concentration of Pindolol can be increased when it is combined with Aceprometazine.
Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Aceprometazine.
Propafenone The serum concentration of Propafenone can be increased when it is combined with Aceprometazine.
Acebutolol The serum concentration of Acebutolol can be increased when it is combined with Aceprometazine.
Nadolol The serum concentration of Nadolol can be increased when it is combined with Aceprometazine.
Bevantolol The serum concentration of Bevantolol can be increased when it is combined with Aceprometazine.
Practolol The serum concentration of Practolol can be increased when it is combined with Aceprometazine.
Penbutolol The serum concentration of Penbutolol can be increased when it is combined with Aceprometazine.
Oxprenolol The serum concentration of Oxprenolol can be increased when it is combined with Aceprometazine.
Dexpropranolol The serum concentration of Dexpropranolol can be increased when it is combined with Aceprometazine.
Celiprolol The serum concentration of Celiprolol can be increased when it is combined with Aceprometazine.
Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Aceprometazine.

Target Protein

Histamine H1 receptor HRH1

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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