Peringatan Keamanan

Agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, restlessness

Acepromazine

DB01614

small molecule experimental vet_approved

Deskripsi

Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.

Struktur Molekul 2D

Berat 326.456
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 3 hours in horses.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid alcohol.
  • 2. Take with food. Food reduces irritation.

Interaksi Obat

1232 Data
Valsartan Acepromazine may decrease the antihypertensive activities of Valsartan.
Ramipril Acepromazine may decrease the antihypertensive activities of Ramipril.
Remikiren Acepromazine may decrease the antihypertensive activities of Remikiren.
Torasemide Acepromazine may decrease the antihypertensive activities of Torasemide.
Guanadrel Acepromazine may decrease the antihypertensive activities of Guanadrel.
Olmesartan Acepromazine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Acepromazine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Acepromazine may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Acepromazine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Acepromazine may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Acepromazine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Acepromazine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Acepromazine may decrease the antihypertensive activities of Trandolapril.
Metolazone Acepromazine may decrease the antihypertensive activities of Metolazone.
Benazepril Acepromazine may decrease the antihypertensive activities of Benazepril.
Bosentan Acepromazine may decrease the antihypertensive activities of Bosentan.
Enalapril Acepromazine may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Acepromazine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Acepromazine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Acepromazine may decrease the antihypertensive activities of Mecamylamine.
Losartan Acepromazine may decrease the antihypertensive activities of Losartan.
Moexipril Acepromazine may decrease the antihypertensive activities of Moexipril.
Eplerenone Acepromazine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Acepromazine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Acepromazine may decrease the antihypertensive activities of Nitroglycerin.
Hydroflumethiazide Acepromazine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Acepromazine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Acepromazine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Acepromazine may decrease the antihypertensive activities of Candesartan cilexetil.
Indapamide Acepromazine may decrease the antihypertensive activities of Indapamide.
Eprosartan Acepromazine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Acepromazine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Acepromazine may decrease the antihypertensive activities of Quinapril.
Telmisartan Acepromazine may decrease the antihypertensive activities of Telmisartan.
Hydrochlorothiazide Acepromazine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Acepromazine may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Acepromazine may decrease the antihypertensive activities of Irbesartan.
Deserpidine Acepromazine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Acepromazine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Acepromazine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Acepromazine may decrease the antihypertensive activities of Diazoxide.
Bretylium Acepromazine may decrease the antihypertensive activities of Bretylium.
Guanethidine Acepromazine may decrease the antihypertensive activities of Guanethidine.
Captopril Acepromazine may decrease the antihypertensive activities of Captopril.
Epoprostenol Acepromazine may decrease the antihypertensive activities of Epoprostenol.
Hydralazine Acepromazine may decrease the antihypertensive activities of Hydralazine.
Polythiazide Acepromazine may decrease the antihypertensive activities of Polythiazide.
Cilazapril Acepromazine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Acepromazine may decrease the antihypertensive activities of Saprisartan.
Spirapril Acepromazine may decrease the antihypertensive activities of Spirapril.
Tienilic acid Acepromazine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Acepromazine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Acepromazine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Acepromazine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Acepromazine may decrease the antihypertensive activities of Diethylnorspermine.
Pinacidil Acepromazine may decrease the antihypertensive activities of Pinacidil.
Temocapril Acepromazine may decrease the antihypertensive activities of Temocapril.
Riociguat Acepromazine may decrease the antihypertensive activities of Riociguat.
Macitentan Acepromazine may decrease the antihypertensive activities of Macitentan.
Aliskiren Acepromazine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Acepromazine may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Acepromazine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Acepromazine may decrease the antihypertensive activities of Enalaprilat.
Selexipag Acepromazine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Acepromazine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Acepromazine may decrease the antihypertensive activities of Imidapril.
BQ-123 Acepromazine may decrease the antihypertensive activities of BQ-123.
Cicletanine Acepromazine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Acepromazine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Acepromazine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Acepromazine may decrease the antihypertensive activities of Guanoxan.
Delapril Acepromazine may decrease the antihypertensive activities of Delapril.
Vincamine Acepromazine may decrease the antihypertensive activities of Vincamine.
Linsidomine Acepromazine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Acepromazine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Acepromazine may decrease the antihypertensive activities of Tolonidine.
Endralazine Acepromazine may decrease the antihypertensive activities of Endralazine.
Cadralazine Acepromazine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Acepromazine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Acepromazine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Acepromazine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Acepromazine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Acepromazine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Acepromazine may decrease the antihypertensive activities of Muzolimine.
Xipamide Acepromazine may decrease the antihypertensive activities of Xipamide.
Candesartan Acepromazine may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Acepromazine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Acepromazine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Acepromazine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Acepromazine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Acepromazine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Acepromazine may decrease the antihypertensive activities of Quinaprilat.
Furosemide Acepromazine may decrease the antihypertensive activities of Furosemide.
Levamlodipine Acepromazine may decrease the antihypertensive activities of Levamlodipine.
Buthiazide Acepromazine may decrease the antihypertensive activities of Buthiazide.
Azilsartan medoxomil Acepromazine may decrease the antihypertensive activities of Azilsartan medoxomil.
Buprenorphine Acepromazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Acepromazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Acepromazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Acepromazine.

Target Protein

D(2) dopamine receptor DRD2
D(1A) dopamine receptor DRD1
5-hydroxytryptamine receptor 2A HTR2A
5-hydroxytryptamine receptor 1A HTR1A
Alpha-1A adrenergic receptor ADRA1A
Alpha-1B adrenergic receptor ADRA1B

Referensi & Sumber

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