Peringatan Keamanan

Overdose symptoms include nausea, emesis (vomiting), hypotension, hypoventilation, dyspnea (shortness of breath), and syncope (fainting)

Amyl Nitrite

DB01612

small molecule approved

Deskripsi

Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use.

Struktur Molekul 2D

Berat 117.1463
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Amyl nitrite vapors are absorbed rapidly through the pulmonary alveoli, manifesting therapeutic effects within one minute after inhalation.

Metabolisme

Hepatic. The drug is metabolized rapidly, probably by hydrolytic denitration; approximately one-third of the inhaled amyl nitrite is excreted in the urine.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid alcohol. The use of alcohol with amyl nitrite may worsen hypotension and has the potential to cause cardiovascular collapse.

Interaksi Obat

380 Data
Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Amyl Nitrite is combined with Duloxetine.
Levodopa The risk or severity of hypotension and orthostatic hypotension can be increased when Amyl Nitrite is combined with Levodopa.
Risperidone Amyl Nitrite may increase the hypotensive activities of Risperidone.
Sildenafil The risk or severity of hypotension can be increased when Amyl Nitrite is combined with Sildenafil.
Tadalafil The risk or severity of hypotension can be increased when Tadalafil is combined with Amyl Nitrite.
Vardenafil The risk or severity of hypotension can be increased when Vardenafil is combined with Amyl Nitrite.
Dipyridamole The risk or severity of hypotension can be increased when Dipyridamole is combined with Amyl Nitrite.
Ibudilast The risk or severity of hypotension can be increased when Ibudilast is combined with Amyl Nitrite.
Avanafil Avanafil may increase the hypotensive activities of Amyl Nitrite.
Udenafil The risk or severity of hypotension can be increased when Udenafil is combined with Amyl Nitrite.
Doxofylline The risk or severity of hypotension can be increased when Doxofylline is combined with Amyl Nitrite.
Mirodenafil The risk or severity of hypotension can be increased when Mirodenafil is combined with Amyl Nitrite.
Fostamatinib The risk or severity of hypotension can be increased when Fostamatinib is combined with Amyl Nitrite.
Prilocaine The risk or severity of methemoglobinemia can be increased when Amyl Nitrite is combined with Prilocaine.
Dapoxetine Dapoxetine may increase the orthostatic hypotensive and hypotensive activities of Amyl Nitrite.
Riociguat Amyl Nitrite may increase the hypotensive activities of Riociguat.
Rosiglitazone The risk or severity of adverse effects can be increased when Amyl Nitrite is combined with Rosiglitazone.
Aripiprazole Aripiprazole may increase the hypotensive activities of Amyl Nitrite.
Aripiprazole lauroxil Aripiprazole lauroxil may increase the hypotensive activities of Amyl Nitrite.
Molsidomine Molsidomine may increase the hypotensive activities of Amyl Nitrite.
Nicorandil Nicorandil may increase the hypotensive activities of Amyl Nitrite.
Dapsone The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Amyl Nitrite.
Ethanol Ethanol may increase the hypotensive and vasodilatory activities of Amyl Nitrite.
Linezolid Linezolid may increase the orthostatic hypotensive activities of Amyl Nitrite.
Furazolidone Furazolidone may increase the orthostatic hypotensive activities of Amyl Nitrite.
Tranylcypromine Tranylcypromine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Phenelzine Phenelzine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Minaprine Minaprine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Selegiline Selegiline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Procarbazine Procarbazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Moclobemide Moclobemide may increase the orthostatic hypotensive activities of Amyl Nitrite.
Isocarboxazid Isocarboxazid may increase the orthostatic hypotensive activities of Amyl Nitrite.
Rasagiline Rasagiline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Pargyline Pargyline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Clorgiline Clorgiline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Iproniazid Iproniazid may increase the orthostatic hypotensive activities of Amyl Nitrite.
Nialamide Nialamide may increase the orthostatic hypotensive activities of Amyl Nitrite.
Safinamide Safinamide may increase the orthostatic hypotensive activities of Amyl Nitrite.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Methylene blue Methylene blue may increase the orthostatic hypotensive activities of Amyl Nitrite.
Hydracarbazine Hydracarbazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Pirlindole Pirlindole may increase the orthostatic hypotensive activities of Amyl Nitrite.
Toloxatone Toloxatone may increase the orthostatic hypotensive activities of Amyl Nitrite.
Benmoxin Benmoxin may increase the orthostatic hypotensive activities of Amyl Nitrite.
Mebanazine Mebanazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Octamoxin Octamoxin may increase the orthostatic hypotensive activities of Amyl Nitrite.
Pheniprazine Pheniprazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Phenoxypropazine Phenoxypropazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Pivhydrazine Pivhydrazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Safrazine Safrazine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Caroxazone Caroxazone may increase the orthostatic hypotensive activities of Amyl Nitrite.
Harmaline Harmaline may increase the orthostatic hypotensive activities of Amyl Nitrite.
Brofaromine Brofaromine may increase the orthostatic hypotensive activities of Amyl Nitrite.
Pentobarbital Pentobarbital may increase the hypotensive activities of Amyl Nitrite.
Secobarbital Secobarbital may increase the hypotensive activities of Amyl Nitrite.
Methohexital Methohexital may increase the hypotensive activities of Amyl Nitrite.
Thiopental Thiopental may increase the hypotensive activities of Amyl Nitrite.
Primidone Primidone may increase the hypotensive activities of Amyl Nitrite.
Methylphenobarbital Methylphenobarbital may increase the hypotensive activities of Amyl Nitrite.
Thiamylal Thiamylal may increase the hypotensive activities of Amyl Nitrite.
Amobarbital Amobarbital may increase the hypotensive activities of Amyl Nitrite.
Hexobarbital Hexobarbital may increase the hypotensive activities of Amyl Nitrite.
Barbital Barbital may increase the hypotensive activities of Amyl Nitrite.
Barbexaclone Barbexaclone may increase the hypotensive activities of Amyl Nitrite.
Butabarbital Butabarbital may increase the hypotensive activities of Amyl Nitrite.
Aldesleukin The risk or severity of adverse effects can be increased when Aldesleukin is combined with Amyl Nitrite.
Streptokinase The risk or severity of adverse effects can be increased when Streptokinase is combined with Amyl Nitrite.
Methyclothiazide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Amyl Nitrite.
Ropinirole The risk or severity of adverse effects can be increased when Ropinirole is combined with Amyl Nitrite.
Morphine The risk or severity of adverse effects can be increased when Morphine is combined with Amyl Nitrite.
Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Amyl Nitrite.
Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Amyl Nitrite.
Clozapine The risk or severity of adverse effects can be increased when Clozapine is combined with Amyl Nitrite.
Triamterene The risk or severity of adverse effects can be increased when Triamterene is combined with Amyl Nitrite.
Pramipexole The risk or severity of adverse effects can be increased when Pramipexole is combined with Amyl Nitrite.
Spironolactone The risk or severity of adverse effects can be increased when Spironolactone is combined with Amyl Nitrite.
Imipramine The risk or severity of adverse effects can be increased when Imipramine is combined with Amyl Nitrite.
Chlorpromazine The risk or severity of adverse effects can be increased when Chlorpromazine is combined with Amyl Nitrite.
Nabilone The risk or severity of adverse effects can be increased when Nabilone is combined with Amyl Nitrite.
Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Amyl Nitrite.
Amiloride The risk or severity of adverse effects can be increased when Amiloride is combined with Amyl Nitrite.
Clofarabine The risk or severity of adverse effects can be increased when Clofarabine is combined with Amyl Nitrite.
Dexmedetomidine The risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Amyl Nitrite.
Thioridazine The risk or severity of adverse effects can be increased when Thioridazine is combined with Amyl Nitrite.
Amphotericin B The risk or severity of adverse effects can be increased when Amphotericin B is combined with Amyl Nitrite.
Furosemide The risk or severity of adverse effects can be increased when Furosemide is combined with Amyl Nitrite.
Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Amyl Nitrite.
Methazolamide The risk or severity of adverse effects can be increased when Methazolamide is combined with Amyl Nitrite.
Tamsulosin The risk or severity of adverse effects can be increased when Tamsulosin is combined with Amyl Nitrite.
Sufentanil The risk or severity of adverse effects can be increased when Sufentanil is combined with Amyl Nitrite.
Apomorphine The risk or severity of adverse effects can be increased when Apomorphine is combined with Amyl Nitrite.
Mannitol The risk or severity of adverse effects can be increased when Mannitol is combined with Amyl Nitrite.
Isoflurane The risk or severity of adverse effects can be increased when Isoflurane is combined with Amyl Nitrite.
Propofol The risk or severity of adverse effects can be increased when Propofol is combined with Amyl Nitrite.
Conivaptan The risk or severity of adverse effects can be increased when Conivaptan is combined with Amyl Nitrite.
Bumetanide The risk or severity of adverse effects can be increased when Bumetanide is combined with Amyl Nitrite.
Remifentanil The risk or severity of adverse effects can be increased when Remifentanil is combined with Amyl Nitrite.
Etacrynic acid The risk or severity of adverse effects can be increased when Etacrynic acid is combined with Amyl Nitrite.
Levosimendan The risk or severity of adverse effects can be increased when Levosimendan is combined with Amyl Nitrite.
Levobupivacaine The risk or severity of adverse effects can be increased when Levobupivacaine is combined with Amyl Nitrite.

Target Protein

Atrial natriuretic peptide receptor 1 NPR1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 3 • International brands: 2
Produk
  • Amyl Nitrite
    Inhalant • 0.3 g/0.3mL • Respiratory (inhalation) • US
  • Amyl Nitrite Vitrellae Bpc Liq 0.33 Ml/cap
    Liquid • 0.33 mL • Respiratory (inhalation) • Canada • Approved
  • Amylnitrite Glass Cap 5min
    Liquid • .3 mL / amp • Respiratory (inhalation) • Canada • Approved
International Brands
  • Aspiral
  • Vaporole

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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