Peringatan Keamanan

In milder cases of phenothiazine overdosage the patient may be agitated, delirious and confused. Frequently he is lethargic or in a comatose state. Twitching, dystonic movements or convulsions may be present and hypotension, cardiovascular collapse, arrhythmias and hypothermia might be observed.

Periciazine

DB01608

small molecule approved investigational

Deskripsi

Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine effects and an action on the extrapyramidal system. It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing hostility, impulsiveness and aggressiveness. Pericyazine, like other phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a central adrenergic blockade.

Struktur Molekul 2D

Berat 365.492
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid alcohol.
  • 2. Take with food. Food reduces irritation.

Interaksi Obat

1241 Data
Valsartan Periciazine may decrease the antihypertensive activities of Valsartan.
Ramipril Periciazine may decrease the antihypertensive activities of Ramipril.
Remikiren Periciazine may decrease the antihypertensive activities of Remikiren.
Torasemide Periciazine may decrease the antihypertensive activities of Torasemide.
Guanadrel Periciazine may decrease the antihypertensive activities of Guanadrel.
Olmesartan Periciazine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Periciazine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Periciazine may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Periciazine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Periciazine may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Periciazine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Periciazine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Periciazine may decrease the antihypertensive activities of Trandolapril.
Metolazone Periciazine may decrease the antihypertensive activities of Metolazone.
Benazepril Periciazine may decrease the antihypertensive activities of Benazepril.
Bosentan Periciazine may decrease the antihypertensive activities of Bosentan.
Enalapril Periciazine may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Periciazine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Periciazine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Periciazine may decrease the antihypertensive activities of Mecamylamine.
Losartan Periciazine may decrease the antihypertensive activities of Losartan.
Moexipril Periciazine may decrease the antihypertensive activities of Moexipril.
Eplerenone Periciazine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Periciazine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Periciazine may decrease the antihypertensive activities of Nitroglycerin.
Hydroflumethiazide Periciazine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Periciazine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Periciazine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Periciazine may decrease the antihypertensive activities of Candesartan cilexetil.
Indapamide Periciazine may decrease the antihypertensive activities of Indapamide.
Eprosartan Periciazine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Periciazine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Periciazine may decrease the antihypertensive activities of Quinapril.
Telmisartan Periciazine may decrease the antihypertensive activities of Telmisartan.
Hydrochlorothiazide Periciazine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Periciazine may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Periciazine may decrease the antihypertensive activities of Irbesartan.
Deserpidine Periciazine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Periciazine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Periciazine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Periciazine may decrease the antihypertensive activities of Diazoxide.
Bretylium Periciazine may decrease the antihypertensive activities of Bretylium.
Guanethidine Periciazine may decrease the antihypertensive activities of Guanethidine.
Captopril Periciazine may decrease the antihypertensive activities of Captopril.
Epoprostenol Periciazine may decrease the antihypertensive activities of Epoprostenol.
Hydralazine Periciazine may decrease the antihypertensive activities of Hydralazine.
Polythiazide Periciazine may decrease the antihypertensive activities of Polythiazide.
Cilazapril Periciazine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Periciazine may decrease the antihypertensive activities of Saprisartan.
Spirapril Periciazine may decrease the antihypertensive activities of Spirapril.
Tienilic acid Periciazine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Periciazine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Periciazine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Periciazine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Periciazine may decrease the antihypertensive activities of Diethylnorspermine.
Pinacidil Periciazine may decrease the antihypertensive activities of Pinacidil.
Temocapril Periciazine may decrease the antihypertensive activities of Temocapril.
Riociguat Periciazine may decrease the antihypertensive activities of Riociguat.
Macitentan Periciazine may decrease the antihypertensive activities of Macitentan.
Aliskiren Periciazine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Periciazine may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Periciazine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Periciazine may decrease the antihypertensive activities of Enalaprilat.
Selexipag Periciazine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Periciazine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Periciazine may decrease the antihypertensive activities of Imidapril.
BQ-123 Periciazine may decrease the antihypertensive activities of BQ-123.
Cicletanine Periciazine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Periciazine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Periciazine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Periciazine may decrease the antihypertensive activities of Guanoxan.
Delapril Periciazine may decrease the antihypertensive activities of Delapril.
Vincamine Periciazine may decrease the antihypertensive activities of Vincamine.
Linsidomine Periciazine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Periciazine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Periciazine may decrease the antihypertensive activities of Tolonidine.
Endralazine Periciazine may decrease the antihypertensive activities of Endralazine.
Cadralazine Periciazine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Periciazine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Periciazine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Periciazine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Periciazine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Periciazine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Periciazine may decrease the antihypertensive activities of Muzolimine.
Xipamide Periciazine may decrease the antihypertensive activities of Xipamide.
Candesartan Periciazine may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Periciazine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Periciazine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Periciazine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Periciazine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Periciazine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Periciazine may decrease the antihypertensive activities of Quinaprilat.
Furosemide Periciazine may decrease the antihypertensive activities of Furosemide.
Levamlodipine Periciazine may decrease the antihypertensive activities of Levamlodipine.
Buthiazide Periciazine may decrease the antihypertensive activities of Buthiazide.
Azilsartan medoxomil Periciazine may decrease the antihypertensive activities of Azilsartan medoxomil.
Buprenorphine Periciazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Periciazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Periciazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Periciazine.

Target Protein

D(1A) dopamine receptor DRD1
Alpha-2A adrenergic receptor ADRA2A
Alpha-1B adrenergic receptor ADRA1B
Androgen receptor AR

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

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International Brands
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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