Pivampicillin

DB01604

small molecule approved

Deskripsi

Pivalate ester analog of ampicillin.

Struktur Molekul 2D

Berat 463.547
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Approximately 1 hour.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorbed following oral administration.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Take with or without food. The absorption is unaffected by food.

Interaksi Obat

192 Data
Methotrexate The excretion of Methotrexate can be decreased when combined with Pivampicillin.
Probenecid The excretion of Pivampicillin can be decreased when combined with Probenecid.
Doxycycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Lymecycline.
Clomocycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Clomocycline.
Tigecycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Oxytetracycline.
Demeclocycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Demeclocycline.
Tetracycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Tetracycline.
Metacycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Metacycline.
Minocycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Minocycline.
Rolitetracycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Rolitetracycline.
Sarecycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Sarecycline.
Eravacycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Eravacycline.
Omadacycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Omadacycline.
Penimepicycline The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Penimepicycline.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Pivampicillin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Pivampicillin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Pivampicillin.
Dicoumarol Pivampicillin may increase the anticoagulant activities of Dicoumarol.
Phenindione Pivampicillin may increase the anticoagulant activities of Phenindione.
Warfarin Pivampicillin may increase the anticoagulant activities of Warfarin.
Phenprocoumon Pivampicillin may increase the anticoagulant activities of Phenprocoumon.
Acenocoumarol Pivampicillin may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin Pivampicillin may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin Pivampicillin may increase the anticoagulant activities of Coumarin.
(R)-warfarin Pivampicillin may increase the anticoagulant activities of (R)-warfarin.
Ethyl biscoumacetate Pivampicillin may increase the anticoagulant activities of Ethyl biscoumacetate.
Fluindione Pivampicillin may increase the anticoagulant activities of Fluindione.
Clorindione Pivampicillin may increase the anticoagulant activities of Clorindione.
Diphenadione Pivampicillin may increase the anticoagulant activities of Diphenadione.
Tioclomarol Pivampicillin may increase the anticoagulant activities of Tioclomarol.
(S)-Warfarin Pivampicillin may increase the anticoagulant activities of (S)-Warfarin.
Diethylstilbestrol The therapeutic efficacy of Diethylstilbestrol can be decreased when used in combination with Pivampicillin.
Etonogestrel The therapeutic efficacy of Etonogestrel can be decreased when used in combination with Pivampicillin.
Desogestrel The therapeutic efficacy of Desogestrel can be decreased when used in combination with Pivampicillin.
Megestrol acetate The therapeutic efficacy of Megestrol acetate can be decreased when used in combination with Pivampicillin.
Levonorgestrel The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Pivampicillin.
Progesterone The therapeutic efficacy of Progesterone can be decreased when used in combination with Pivampicillin.
Medroxyprogesterone acetate The therapeutic efficacy of Medroxyprogesterone acetate can be decreased when used in combination with Pivampicillin.
Norethisterone The therapeutic efficacy of Norethisterone can be decreased when used in combination with Pivampicillin.
Estradiol The therapeutic efficacy of Estradiol can be decreased when used in combination with Pivampicillin.
Ethynodiol diacetate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Pivampicillin.
Mifepristone The therapeutic efficacy of Mifepristone can be decreased when used in combination with Pivampicillin.
Norgestimate The therapeutic efficacy of Norgestimate can be decreased when used in combination with Pivampicillin.
Ethinylestradiol The therapeutic efficacy of Ethinylestradiol can be decreased when used in combination with Pivampicillin.
Mestranol The therapeutic efficacy of Mestranol can be decreased when used in combination with Pivampicillin.
Drospirenone The therapeutic efficacy of Drospirenone can be decreased when used in combination with Pivampicillin.
Estrone sulfate The therapeutic efficacy of Estrone sulfate can be decreased when used in combination with Pivampicillin.
Octylphenoxy polyethoxyethanol The therapeutic efficacy of Octylphenoxy polyethoxyethanol can be decreased when used in combination with Pivampicillin.
Cyproterone acetate The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Pivampicillin.
Trestolone The therapeutic efficacy of Trestolone can be decreased when used in combination with Pivampicillin.
Norelgestromin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Pivampicillin.
Gestodene The therapeutic efficacy of Gestodene can be decreased when used in combination with Pivampicillin.
Hydroxyprogesterone caproate The therapeutic efficacy of Hydroxyprogesterone caproate can be decreased when used in combination with Pivampicillin.
Ulipristal The therapeutic efficacy of Ulipristal can be decreased when used in combination with Pivampicillin.
Dienogest The therapeutic efficacy of Dienogest can be decreased when used in combination with Pivampicillin.
Norethynodrel The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Pivampicillin.
Norgestrel The therapeutic efficacy of Norgestrel can be decreased when used in combination with Pivampicillin.
Cloprostenol The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Pivampicillin.
Gestrinone The therapeutic efficacy of Gestrinone can be decreased when used in combination with Pivampicillin.
Nomegestrol The therapeutic efficacy of Nomegestrol can be decreased when used in combination with Pivampicillin.
Lynestrenol The therapeutic efficacy of Lynestrenol can be decreased when used in combination with Pivampicillin.
Gossypol The therapeutic efficacy of Gossypol can be decreased when used in combination with Pivampicillin.
Ormeloxifene The therapeutic efficacy of Ormeloxifene can be decreased when used in combination with Pivampicillin.
Chlormadinone The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Pivampicillin.
Norgestrienone The therapeutic efficacy of Norgestrienone can be decreased when used in combination with Pivampicillin.
Quingestanol The therapeutic efficacy of Quingestanol can be decreased when used in combination with Pivampicillin.
Demegestone The therapeutic efficacy of Demegestone can be decreased when used in combination with Pivampicillin.
Etynodiol The therapeutic efficacy of Etynodiol can be decreased when used in combination with Pivampicillin.
Testosterone enanthate The therapeutic efficacy of Testosterone enanthate can be decreased when used in combination with Pivampicillin.
Estradiol benzoate The therapeutic efficacy of Estradiol benzoate can be decreased when used in combination with Pivampicillin.
Estradiol cypionate The therapeutic efficacy of Estradiol cypionate can be decreased when used in combination with Pivampicillin.
Estradiol valerate The therapeutic efficacy of Estradiol valerate can be decreased when used in combination with Pivampicillin.
Nomegestrol acetate The therapeutic efficacy of Nomegestrol acetate can be decreased when used in combination with Pivampicillin.
Norethindrone enanthate The therapeutic efficacy of Norethindrone enanthate can be decreased when used in combination with Pivampicillin.
Capreomycin The serum concentration of Capreomycin can be decreased when it is combined with Pivampicillin.
Framycetin The serum concentration of Framycetin can be decreased when it is combined with Pivampicillin.
Amikacin The serum concentration of Amikacin can be decreased when it is combined with Pivampicillin.
Tobramycin The serum concentration of Tobramycin can be decreased when it is combined with Pivampicillin.
Gentamicin The serum concentration of Gentamicin can be decreased when it is combined with Pivampicillin.
Netilmicin The serum concentration of Netilmicin can be decreased when it is combined with Pivampicillin.
Neomycin The serum concentration of Neomycin can be decreased when it is combined with Pivampicillin.
Streptomycin The serum concentration of Streptomycin can be decreased when it is combined with Pivampicillin.
Kanamycin The serum concentration of Kanamycin can be decreased when it is combined with Pivampicillin.
Paromomycin The serum concentration of Paromomycin can be decreased when it is combined with Pivampicillin.
Ribostamycin The serum concentration of Ribostamycin can be decreased when it is combined with Pivampicillin.
Geneticin The serum concentration of Geneticin can be decreased when it is combined with Pivampicillin.
Apramycin The serum concentration of Apramycin can be decreased when it is combined with Pivampicillin.
Gentamicin C1a The serum concentration of Gentamicin C1a can be decreased when it is combined with Pivampicillin.
Neamine The serum concentration of Neamine can be decreased when it is combined with Pivampicillin.
Arbekacin The serum concentration of Arbekacin can be decreased when it is combined with Pivampicillin.
Puromycin The serum concentration of Puromycin can be decreased when it is combined with Pivampicillin.
Dihydrostreptomycin The serum concentration of Dihydrostreptomycin can be decreased when it is combined with Pivampicillin.
Hygromycin B The serum concentration of Hygromycin B can be decreased when it is combined with Pivampicillin.
Sisomicin The serum concentration of Sisomicin can be decreased when it is combined with Pivampicillin.
Plazomicin The serum concentration of Plazomicin can be decreased when it is combined with Pivampicillin.
Isepamicin The serum concentration of Isepamicin can be decreased when it is combined with Pivampicillin.
Colistin The serum concentration of Colistin can be decreased when it is combined with Pivampicillin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Pivampicillin.

Target Protein

Penicillin-binding protein 1A pbpA

Referensi & Sumber

Artikel (PubMed)
  • PMID: 20398122
    Albertson TE, Louie S, Chan AL: The diagnosis and treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease and chronic bronchitis. J Am Geriatr Soc. 2010 Mar;58(3):570-9. doi: 10.1111/j.1532-5415.2010.02741.x.
  • PMID: 15793098
    Chanteux H, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM: Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin. Antimicrob Agents Chemother. 2005 Apr;49(4):1279-88.

Contoh Produk & Brand

Produk: 2 • International brands: 1
Produk
  • Pondocillin Pws 175mg/5ml
    Powder, for solution • 175 mg / 5 mL • Oral • Canada • Approved
  • Pondocillin Tab 500mg
    Tablet • 500 mg • Oral • Canada • Approved
International Brands
  • Pondocillin

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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