The onset of impairment of consciousness is relatively rapid in benzodiazepine poisoning. Onset is more rapid following larger doses and with agents of shorter duration of action. The most common and initial symptom is somnolence. This may progress to coma Grade I or Grade II following very large ingestions.
Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Hydrocodone | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Magnesium sulfate | The therapeutic efficacy of Cinolazepam can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Cinolazepam may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Mirtazapine | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Orphenadrine | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Pramipexole | Cinolazepam may increase the sedative activities of Pramipexole. |
| Ropinirole | Cinolazepam may increase the sedative activities of Ropinirole. |
| Rotigotine | Cinolazepam may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Cinolazepam. |
| Suvorexant | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Thalidomide | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Clozapine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Clozapine. |
| Methadone | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Methadone. |
| Phenytoin | The serum concentration of Phenytoin can be increased when it is combined with Cinolazepam. |
| Fosphenytoin | The serum concentration of Fosphenytoin can be increased when it is combined with Cinolazepam. |
| Sodium oxybate | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Teduglutide | The serum concentration of Cinolazepam can be increased when it is combined with Teduglutide. |
| Flumazenil | Flumazenil may decrease the sedative activities of Cinolazepam. |
| Ethanol | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Cinolazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Cinolazepam. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Dapoxetine. |
| Milnacipran | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Seproxetine. |
| Indalpine | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Alaproclate. |
| Amitriptyline | The risk or severity of CNS depression can be increased when Amitriptyline is combined with Cinolazepam. |
| Cyproheptadine | The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Cinolazepam. |
| Imipramine | The risk or severity of CNS depression can be increased when Imipramine is combined with Cinolazepam. |
| Nortriptyline | The risk or severity of CNS depression can be increased when Nortriptyline is combined with Cinolazepam. |
| Amoxapine | The risk or severity of CNS depression can be increased when Amoxapine is combined with Cinolazepam. |
| Propiomazine | The risk or severity of CNS depression can be increased when Propiomazine is combined with Cinolazepam. |
| Maprotiline | The risk or severity of CNS depression can be increased when Maprotiline is combined with Cinolazepam. |
| Doxepin | The risk or severity of CNS depression can be increased when Doxepin is combined with Cinolazepam. |
| Desipramine | The risk or severity of CNS depression can be increased when Desipramine is combined with Cinolazepam. |
| Pizotifen | The risk or severity of CNS depression can be increased when Cinolazepam is combined with Pizotifen. |
| Dosulepin | The risk or severity of CNS depression can be increased when Cinolazepam is combined with Dosulepin. |
| Olanzapine | The risk or severity of CNS depression can be increased when Olanzapine is combined with Cinolazepam. |
| Zopiclone | The risk or severity of adverse effects can be increased when Cinolazepam is combined with Zopiclone. |
| Caffeine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Caffeine. |
| Theophylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Theophylline. |
| Dyphylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Dyphylline. |
| Pentoxifylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Pentoxifylline. |
| Mercaptopurine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Mercaptopurine. |
| Aminophylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Aminophylline. |
| Oxtriphylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Oxtriphylline. |
| Theobromine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Theobromine. |
| Fenethylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Fenethylline. |
| 8-azaguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 8-azaguanine. |
| 7,9-Dimethylguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 7,9-Dimethylguanine. |
| Xanthine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Xanthine. |
| 7-Deazaguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 7-Deazaguanine. |
| Guanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Guanine. |
| 9-Methylguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 9-Methylguanine. |
| Peldesine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Peldesine. |
| Hypoxanthine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Hypoxanthine. |
| 9-Deazaguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 9-Deazaguanine. |
| Propentofylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Propentofylline. |
| Valomaciclovir | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Valomaciclovir. |
| 3-isobutyl-1-methyl-7H-xanthine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 3-isobutyl-1-methyl-7H-xanthine. |
| Uric acid | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Uric acid. |
| Doxofylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Doxofylline. |
| 6-O-benzylguanine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 6-O-benzylguanine. |
| Lisofylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Lisofylline. |
| Lobucavir | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Lobucavir. |
| Cafedrine | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Cafedrine. |
| Theodrenaline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Theodrenaline. |
| Bamifylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Bamifylline. |
| Proxyphylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Proxyphylline. |
| Acefylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Acefylline. |
| Etamiphylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Etamiphylline. |
| Pentifylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Pentifylline. |
| Bufylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Bufylline. |
| Bromotheophylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Bromotheophylline. |
| Furafylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with Furafylline. |
| 8-chlorotheophylline | The therapeutic efficacy of Cinolazepam can be decreased when used in combination with 8-chlorotheophylline. |