Peringatan Keamanan

Sulfamerazine may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns.

Sulfamerazine

DB01581

small molecule approved vet_approved

Deskripsi

A sulfanilamide that is used as an antibacterial agent.

Struktur Molekul 2D

Berat 264.304
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed following oral administration.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

167 Data
Nicotine The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Nicotine.
Mecamylamine The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Mecamylamine.
Pentolinium The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Pentolinium.
Trimethaphan The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Trimethaphan.
Hexamethonium The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Hexamethonium.
Cyclopentamine The risk or severity of adverse effects can be increased when Sulfamerazine is combined with Cyclopentamine.
Methotrexate The protein binding of Methotrexate can be increased when combined with Sulfamerazine.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Sulfamerazine.
Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Sulfamerazine.
Dexketoprofen The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Sulfamerazine.
Cyclosporine The risk or severity of renal failure can be increased when Sulfamerazine is combined with Cyclosporine.
Methenamine Methenamine can cause a decrease in the absorption of Sulfamerazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Sulfamerazine.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Sulfamerazine.
Insulin human The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin human.
Insulin lispro The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin lispro.
Insulin glargine The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin glargine.
Insulin pork The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin pork.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Sulfamerazine.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Sulfamerazine.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Sulfamerazine.
Disopyramide The therapeutic efficacy of Disopyramide can be increased when used in combination with Sulfamerazine.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfamerazine.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Sulfamerazine.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Sulfamerazine.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfamerazine.
Quinine The therapeutic efficacy of Quinine can be increased when used in combination with Sulfamerazine.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Sulfamerazine.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Sulfamerazine.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Sulfamerazine.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Sulfamerazine.
Mifepristone The therapeutic efficacy of Mifepristone can be increased when used in combination with Sulfamerazine.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Sulfamerazine.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Sulfamerazine.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Sulfamerazine.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Sulfamerazine.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Sulfamerazine.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Sulfamerazine.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Sulfamerazine.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Sulfamerazine.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Sulfamerazine.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sulfamerazine.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Sulfamerazine.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sulfamerazine.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Sulfamerazine.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Sulfamerazine.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Sulfamerazine.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Sulfamerazine.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Sulfamerazine.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Sulfamerazine.
Insulin aspart The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin aspart.
Insulin detemir The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin detemir.
Insulin glulisine The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin glulisine.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Sulfamerazine.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Sulfamerazine.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Sulfamerazine.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Sulfamerazine.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Sulfamerazine.
NN344 The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with NN344.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Sulfamerazine.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Sulfamerazine.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfamerazine.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Sulfamerazine.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Sulfamerazine.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Sulfamerazine.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Sulfamerazine.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Sulfamerazine.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sulfamerazine.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Sulfamerazine.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Sulfamerazine.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Sulfamerazine.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfamerazine.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Sulfamerazine.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Sulfamerazine.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Sulfamerazine.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Sulfamerazine.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Sulfamerazine.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Sulfamerazine.
Insulin beef The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin beef.
Insulin degludec The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin degludec.
Insulin peglispro The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin peglispro.
Insulin tregopil The risk or severity of hypoglycemia can be increased when Sulfamerazine is combined with Insulin tregopil.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Sulfamerazine.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Sulfamerazine.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Sulfamerazine.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Sulfamerazine.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Sulfamerazine.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sulfamerazine.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Sulfamerazine.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Sulfamerazine.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Sulfamerazine.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sulfamerazine.
Anagliptin The therapeutic efficacy of Anagliptin can be increased when used in combination with Sulfamerazine.
Evogliptin The therapeutic efficacy of Evogliptin can be increased when used in combination with Sulfamerazine.
Sotagliflozin The therapeutic efficacy of Sotagliflozin can be increased when used in combination with Sulfamerazine.
Balaglitazone The therapeutic efficacy of Balaglitazone can be increased when used in combination with Sulfamerazine.
Remogliflozin etabonate The therapeutic efficacy of Remogliflozin etabonate can be increased when used in combination with Sulfamerazine.
Carbutamide The therapeutic efficacy of Carbutamide can be increased when used in combination with Sulfamerazine.
Guar gum The therapeutic efficacy of Guar gum can be increased when used in combination with Sulfamerazine.
Metahexamide The therapeutic efficacy of Metahexamide can be increased when used in combination with Sulfamerazine.

Target Protein

Dihydropteroate synthase folP

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 2 • International brands: 0
Produk
  • Trisulfaminic Sus
    Suspension • - • Oral • Canada • Approved
  • Trisulfaminic Tab
    Tablet • - • Oral • Canada • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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