Androstenedione

DB01536

small molecule experimental illicit

Deskripsi

A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.

Struktur Molekul 2D

Berat 286.4085
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

168 Data
Flunisolide The risk or severity of edema formation can be increased when Androstenedione is combined with Flunisolide.
Beclomethasone dipropionate The risk or severity of edema formation can be increased when Androstenedione is combined with Beclomethasone dipropionate.
Betamethasone The risk or severity of edema formation can be increased when Androstenedione is combined with Betamethasone.
Fluticasone propionate The risk or severity of edema formation can be increased when Androstenedione is combined with Fluticasone propionate.
Fluocinolone acetonide The risk or severity of edema formation can be increased when Androstenedione is combined with Fluocinolone acetonide.
Triamcinolone The risk or severity of edema formation can be increased when Androstenedione is combined with Triamcinolone.
Prednisone The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisone.
Fludrocortisone The risk or severity of edema formation can be increased when Androstenedione is combined with Fludrocortisone.
Hydrocortisone The risk or severity of edema formation can be increased when Androstenedione is combined with Hydrocortisone.
Prednisolone The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisolone.
Methylprednisolone The risk or severity of edema formation can be increased when Androstenedione is combined with Methylprednisolone.
Trilostane The risk or severity of edema formation can be increased when Androstenedione is combined with Trilostane.
Corticotropin The risk or severity of edema formation can be increased when Androstenedione is combined with Corticotropin.
Cortisone acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Cortisone acetate.
Paramethasone The risk or severity of edema formation can be increased when Androstenedione is combined with Paramethasone.
Ciclesonide The risk or severity of edema formation can be increased when Androstenedione is combined with Ciclesonide.
Aldosterone The risk or severity of edema formation can be increased when Androstenedione is combined with Aldosterone.
Fluticasone furoate The risk or severity of edema formation can be increased when Androstenedione is combined with Fluticasone furoate.
Fluprednidene The risk or severity of edema formation can be increased when Androstenedione is combined with Fluprednidene.
Tixocortol The risk or severity of edema formation can be increased when Androstenedione is combined with Tixocortol.
Fluprednisolone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluprednisolone.
Meprednisone The risk or severity of edema formation can be increased when Androstenedione is combined with Meprednisone.
Dexamethasone isonicotinate The risk or severity of edema formation can be increased when Androstenedione is combined with Dexamethasone isonicotinate.
Melengestrol The risk or severity of edema formation can be increased when Androstenedione is combined with Melengestrol.
Deflazacort The risk or severity of edema formation can be increased when Androstenedione is combined with Deflazacort.
Cortivazol The risk or severity of edema formation can be increased when Androstenedione is combined with Cortivazol.
Prednylidene The risk or severity of edema formation can be increased when Androstenedione is combined with Prednylidene.
Fluocortin The risk or severity of edema formation can be increased when Androstenedione is combined with Fluocortin.
Fluperolone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluperolone.
Cloprednol The risk or severity of edema formation can be increased when Androstenedione is combined with Cloprednol.
Fluclorolone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluclorolone.
Fluticasone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluticasone.
Mometasone furoate The risk or severity of edema formation can be increased when Androstenedione is combined with Mometasone furoate.
Hydrocortisone acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Hydrocortisone acetate.
Hydrocortisone cypionate The risk or severity of edema formation can be increased when Androstenedione is combined with Hydrocortisone cypionate.
Hydrocortisone succinate The risk or severity of edema formation can be increased when Androstenedione is combined with Hydrocortisone succinate.
Prednisolone phosphate The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisolone phosphate.
Prednisolone hemisuccinate The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisolone hemisuccinate.
Methylprednisolone hemisuccinate The risk or severity of edema formation can be increased when Androstenedione is combined with Methylprednisolone hemisuccinate.
Prednisone acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisone acetate.
Clocortolone acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Clocortolone acetate.
Melengestrol acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Melengestrol acetate.
Betamethasone phosphate The risk or severity of edema formation can be increased when Androstenedione is combined with Betamethasone phosphate.
Cortisone The risk or severity of edema formation can be increased when Androstenedione is combined with Cortisone.
Dexamethasone The risk or severity of edema formation can be increased when Androstenedione is combined with Dexamethasone.
Budesonide The risk or severity of edema formation can be increased when Androstenedione is combined with Budesonide.
Clobetasol propionate The risk or severity of edema formation can be increased when Androstenedione is combined with Clobetasol propionate.
Fluocinonide The risk or severity of edema formation can be increased when Androstenedione is combined with Fluocinonide.
Hydrocortisone butyrate The risk or severity of edema formation can be increased when Androstenedione is combined with Hydrocortisone butyrate.
Desoximetasone The risk or severity of edema formation can be increased when Androstenedione is combined with Desoximetasone.
Mometasone The risk or severity of edema formation can be increased when Androstenedione is combined with Mometasone.
Fluocortolone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluocortolone.
Prednisolone acetate The risk or severity of edema formation can be increased when Androstenedione is combined with Prednisolone acetate.
Fluorometholone The risk or severity of edema formation can be increased when Androstenedione is combined with Fluorometholone.
Difluocortolone The risk or severity of edema formation can be increased when Androstenedione is combined with Difluocortolone.
Flumethasone The risk or severity of edema formation can be increased when Androstenedione is combined with Flumethasone.
Methylprednisolone aceponate The risk or severity of edema formation can be increased when Androstenedione is combined with Methylprednisolone aceponate.
Pitolisant The serum concentration of Androstenedione can be decreased when it is combined with Pitolisant.
Metreleptin The metabolism of Androstenedione can be increased when combined with Metreleptin.
Cenobamate The serum concentration of Androstenedione can be decreased when it is combined with Cenobamate.
Ritonavir The serum concentration of Androstenedione can be increased when it is combined with Ritonavir.
Haloperidol The serum concentration of Haloperidol can be increased when it is combined with Androstenedione.
Tucatinib The metabolism of Tucatinib can be decreased when combined with Androstenedione.
Abametapir The serum concentration of Androstenedione can be increased when it is combined with Abametapir.
Satralizumab The serum concentration of Androstenedione can be decreased when it is combined with Satralizumab.
Sotorasib The serum concentration of Androstenedione can be decreased when it is combined with Sotorasib.
Cyclosporine The metabolism of Androstenedione can be decreased when combined with Cyclosporine.
Fluvoxamine The metabolism of Androstenedione can be decreased when combined with Fluvoxamine.
Fluconazole The metabolism of Androstenedione can be decreased when combined with Fluconazole.
Erythromycin The serum concentration of Androstenedione can be increased when it is combined with Erythromycin.
Ziprasidone The metabolism of Androstenedione can be decreased when combined with Ziprasidone.
Isradipine The metabolism of Androstenedione can be decreased when combined with Isradipine.
Diltiazem The metabolism of Androstenedione can be decreased when combined with Diltiazem.
Clozapine The metabolism of Androstenedione can be decreased when combined with Clozapine.
Ciprofloxacin The metabolism of Androstenedione can be decreased when combined with Ciprofloxacin.
Nicardipine The metabolism of Androstenedione can be decreased when combined with Nicardipine.
Verapamil The metabolism of Androstenedione can be decreased when combined with Verapamil.
Aprepitant The metabolism of Androstenedione can be decreased when combined with Aprepitant.
Isoniazid The metabolism of Androstenedione can be decreased when combined with Isoniazid.
Primaquine The metabolism of Androstenedione can be decreased when combined with Primaquine.
Miconazole The metabolism of Androstenedione can be decreased when combined with Miconazole.
Fusidic acid The metabolism of Androstenedione can be decreased when combined with Fusidic acid.
Zimelidine The metabolism of Androstenedione can be decreased when combined with Zimelidine.
Dronedarone The metabolism of Androstenedione can be decreased when combined with Dronedarone.
Milnacipran The metabolism of Androstenedione can be decreased when combined with Milnacipran.
Simeprevir The metabolism of Androstenedione can be decreased when combined with Simeprevir.
Isavuconazonium The metabolism of Androstenedione can be decreased when combined with Isavuconazonium.
Desvenlafaxine The metabolism of Androstenedione can be decreased when combined with Desvenlafaxine.
Nilvadipine The metabolism of Androstenedione can be decreased when combined with Nilvadipine.
Seproxetine The metabolism of Androstenedione can be decreased when combined with Seproxetine.
Linagliptin The metabolism of Androstenedione can be decreased when combined with Linagliptin.
Indalpine The metabolism of Androstenedione can be decreased when combined with Indalpine.
Netupitant The metabolism of Androstenedione can be decreased when combined with Netupitant.
Barnidipine The metabolism of Androstenedione can be decreased when combined with Barnidipine.
Benidipine The metabolism of Androstenedione can be decreased when combined with Benidipine.
Venetoclax The metabolism of Androstenedione can be decreased when combined with Venetoclax.
Isavuconazole The metabolism of Androstenedione can be decreased when combined with Isavuconazole.
Fosnetupitant The metabolism of Androstenedione can be decreased when combined with Fosnetupitant.
Berotralstat The metabolism of Androstenedione can be decreased when combined with Berotralstat.
Midostaurin The metabolism of Androstenedione can be decreased when combined with Midostaurin.

Target Protein

Aromatase CYP19A1
17-beta-hydroxysteroid dehydrogenase type 1 HSD17B1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1
Aldo-keto reductase family 1 member C3 AKR1C3
6-deoxyerythronolide B hydroxylase eryF

Referensi & Sumber

Synthesis reference: Angela M. H. Brodie, Harry J. Brodie, David A. Marsh, "Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis." U.S. Patent US4235893, issued October, 1962.

Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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