Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially). Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 microgram. It is marketed under the trade name Wildnil as a general anaesthetic agent for large animals. Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans. Currently sufentanil, approximately 10–20 times less potent (500 to 1000 times the efficacy of morphine per weight) than carfentanil, is the maximum strength fentanyl analog for use in humans.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Hydrocodone | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Magnesium sulfate | The therapeutic efficacy of Carfentanil can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Carfentanil may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Orphenadrine | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Pramipexole | Carfentanil may increase the sedative activities of Pramipexole. |
| Ropinirole | Carfentanil may increase the sedative activities of Ropinirole. |
| Rotigotine | Carfentanil may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Carfentanil. |
| Sodium oxybate | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Thalidomide | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Alvimopan | The risk or severity of adverse effects can be increased when Carfentanil is combined with Alvimopan. |
| Desmopressin | The risk or severity of hyponatremia can be increased when Carfentanil is combined with Desmopressin. |
| Morphine | The risk or severity of adverse effects can be increased when Morphine is combined with Carfentanil. |
| Codeine | The risk or severity of adverse effects can be increased when Codeine is combined with Carfentanil. |
| Hydromorphone | The risk or severity of adverse effects can be increased when Hydromorphone is combined with Carfentanil. |
| Meperidine | The risk or severity of adverse effects can be increased when Meperidine is combined with Carfentanil. |
| Oxycodone | The risk or severity of adverse effects can be increased when Oxycodone is combined with Carfentanil. |
| Dextropropoxyphene | The risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Carfentanil. |
| Naltrexone | The therapeutic efficacy of Carfentanil can be decreased when used in combination with Naltrexone. |
| Sufentanil | The risk or severity of adverse effects can be increased when Sufentanil is combined with Carfentanil. |
| Alfentanil | The risk or severity of adverse effects can be increased when Alfentanil is combined with Carfentanil. |
| Fentanyl | The risk or severity of adverse effects can be increased when Fentanyl is combined with Carfentanil. |
| Levorphanol | The risk or severity of adverse effects can be increased when Levorphanol is combined with Carfentanil. |
| Remifentanil | The risk or severity of adverse effects can be increased when Remifentanil is combined with Carfentanil. |
| Diphenoxylate | The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Carfentanil. |
| Oxymorphone | The risk or severity of adverse effects can be increased when Oxymorphone is combined with Carfentanil. |
| Dezocine | The risk or severity of adverse effects can be increased when Dezocine is combined with Carfentanil. |
| Methadyl acetate | The risk or severity of adverse effects can be increased when Methadyl acetate is combined with Carfentanil. |
| Dihydroetorphine | The risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Carfentanil. |
| Diamorphine | The risk or severity of adverse effects can be increased when Diamorphine is combined with Carfentanil. |
| Bezitramide | The risk or severity of adverse effects can be increased when Bezitramide is combined with Carfentanil. |
| Ethylmorphine | The risk or severity of adverse effects can be increased when Ethylmorphine is combined with Carfentanil. |
| Etorphine | The risk or severity of adverse effects can be increased when Etorphine is combined with Carfentanil. |
| Dextromoramide | The risk or severity of adverse effects can be increased when Dextromoramide is combined with Carfentanil. |
| Desomorphine | The risk or severity of adverse effects can be increased when Desomorphine is combined with Carfentanil. |
| Dihydrocodeine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Dihydrocodeine. |
| Alphacetylmethadol | The risk or severity of adverse effects can be increased when Carfentanil is combined with Alphacetylmethadol. |
| Dihydromorphine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Dihydromorphine. |
| Ketobemidone | The risk or severity of adverse effects can be increased when Carfentanil is combined with Ketobemidone. |
| DPDPE | The risk or severity of adverse effects can be increased when Carfentanil is combined with DPDPE. |
| Lofentanil | The risk or severity of adverse effects can be increased when Carfentanil is combined with Lofentanil. |
| Opium | The risk or severity of adverse effects can be increased when Carfentanil is combined with Opium. |
| Normethadone | The risk or severity of adverse effects can be increased when Carfentanil is combined with Normethadone. |
| Piritramide | The risk or severity of adverse effects can be increased when Carfentanil is combined with Piritramide. |
| Alphaprodine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Alphaprodine. |
| Nicomorphine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Nicomorphine. |
| Meptazinol | The therapeutic efficacy of Carfentanil can be decreased when used in combination with Meptazinol. |
| Phenoperidine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Phenoperidine. |
| Phenazocine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Phenazocine. |
| Tilidine | The risk or severity of adverse effects can be increased when Carfentanil is combined with Tilidine. |
| Carfentanil, C-11 | The risk or severity of adverse effects can be increased when Carfentanil is combined with Carfentanil, C-11. |
| Naloxegol | The risk or severity of adverse effects can be increased when Carfentanil is combined with Naloxegol. |
| Benzhydrocodone | The risk or severity of adverse effects can be increased when Carfentanil is combined with Benzhydrocodone. |
| Pegvisomant | The therapeutic efficacy of Pegvisomant can be decreased when used in combination with Carfentanil. |
| Succinylcholine | The risk or severity of bradycardia can be increased when Succinylcholine is combined with Carfentanil. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Carfentanil. |
| Linezolid | The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Carfentanil. |
| Mirtazapine | Carfentanil may increase the serotonergic activities of Mirtazapine. |
| Fluvoxamine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Fluvoxamine. |
| Citalopram | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Citalopram. |
| Duloxetine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Duloxetine. |
| Paroxetine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Paroxetine. |
| Sertraline | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Sertraline. |
| Sibutramine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Sibutramine. |
| Nefazodone | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Nefazodone. |
| Zimelidine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Zimelidine. |
| Dapoxetine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Dapoxetine. |
| Milnacipran | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Carfentanil. |
| Seproxetine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Seproxetine. |
| Levomilnacipran | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Levomilnacipran. |
| Indalpine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Indalpine. |
| Ritanserin | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Ritanserin. |
| Alaproclate | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Alaproclate. |
| Ethanol | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Carfentanil may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Carfentanil. |
| Phentermine | Phentermine may increase the analgesic activities of Carfentanil. |
| Pseudoephedrine | Pseudoephedrine may increase the analgesic activities of Carfentanil. |
| Benzphetamine | Benzphetamine may increase the analgesic activities of Carfentanil. |
| Diethylpropion | Diethylpropion may increase the analgesic activities of Carfentanil. |
| Lisdexamfetamine | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Lisdexamfetamine. |
| Mephentermine | Mephentermine may increase the analgesic activities of Carfentanil. |
| MMDA | MMDA may increase the analgesic activities of Carfentanil. |
| Midomafetamine | Midomafetamine may increase the analgesic activities of Carfentanil. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may increase the analgesic activities of Carfentanil. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may increase the analgesic activities of Carfentanil. |