Etorphine

DB01497

small molecule illicit vet_approved

Deskripsi

A narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for research purposes. Etorphine is only available to the patients under an official prescription. In the US, Etorphine is listed as a Schedule I drug, although Etorphine hydrochloride is classified as Schedule II.

Struktur Molekul 2D

Berat 411.5338
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

915 Data
Buprenorphine Etorphine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Hydrocodone Etorphine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Magnesium sulfate The therapeutic efficacy of Etorphine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Etorphine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Etorphine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Orphenadrine Etorphine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Etorphine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Pramipexole Etorphine may increase the sedative activities of Pramipexole.
Ropinirole Etorphine may increase the sedative activities of Ropinirole.
Rotigotine Etorphine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Etorphine.
Sodium oxybate Etorphine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Etorphine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Thalidomide Etorphine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Etorphine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Alvimopan The risk or severity of adverse effects can be increased when Etorphine is combined with Alvimopan.
Desmopressin The risk or severity of hyponatremia can be increased when Etorphine is combined with Desmopressin.
Morphine The risk or severity of adverse effects can be increased when Morphine is combined with Etorphine.
Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Etorphine.
Hydromorphone The risk or severity of adverse effects can be increased when Hydromorphone is combined with Etorphine.
Meperidine The risk or severity of adverse effects can be increased when Meperidine is combined with Etorphine.
Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Etorphine.
Dextropropoxyphene The risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Etorphine.
Naltrexone The therapeutic efficacy of Etorphine can be decreased when used in combination with Naltrexone.
Sufentanil The risk or severity of adverse effects can be increased when Sufentanil is combined with Etorphine.
Alfentanil The risk or severity of adverse effects can be increased when Alfentanil is combined with Etorphine.
Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Etorphine.
Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Etorphine.
Remifentanil The risk or severity of adverse effects can be increased when Remifentanil is combined with Etorphine.
Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Etorphine.
Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Etorphine.
Dezocine The risk or severity of adverse effects can be increased when Dezocine is combined with Etorphine.
Methadyl acetate The risk or severity of adverse effects can be increased when Methadyl acetate is combined with Etorphine.
Dihydroetorphine The risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Etorphine.
Diamorphine The risk or severity of adverse effects can be increased when Diamorphine is combined with Etorphine.
Bezitramide The risk or severity of adverse effects can be increased when Bezitramide is combined with Etorphine.
Ethylmorphine The risk or severity of adverse effects can be increased when Ethylmorphine is combined with Etorphine.
Dextromoramide The risk or severity of adverse effects can be increased when Etorphine is combined with Dextromoramide.
Desomorphine The risk or severity of adverse effects can be increased when Etorphine is combined with Desomorphine.
Carfentanil The risk or severity of adverse effects can be increased when Etorphine is combined with Carfentanil.
Dihydrocodeine The risk or severity of adverse effects can be increased when Etorphine is combined with Dihydrocodeine.
Alphacetylmethadol The risk or severity of adverse effects can be increased when Etorphine is combined with Alphacetylmethadol.
Dihydromorphine The risk or severity of adverse effects can be increased when Etorphine is combined with Dihydromorphine.
Ketobemidone The risk or severity of adverse effects can be increased when Etorphine is combined with Ketobemidone.
DPDPE The risk or severity of adverse effects can be increased when Etorphine is combined with DPDPE.
Lofentanil The risk or severity of adverse effects can be increased when Etorphine is combined with Lofentanil.
Opium The risk or severity of adverse effects can be increased when Etorphine is combined with Opium.
Normethadone The risk or severity of adverse effects can be increased when Etorphine is combined with Normethadone.
Piritramide The risk or severity of adverse effects can be increased when Etorphine is combined with Piritramide.
Alphaprodine The risk or severity of adverse effects can be increased when Etorphine is combined with Alphaprodine.
Nicomorphine The risk or severity of adverse effects can be increased when Etorphine is combined with Nicomorphine.
Meptazinol The therapeutic efficacy of Etorphine can be decreased when used in combination with Meptazinol.
Phenoperidine The risk or severity of adverse effects can be increased when Etorphine is combined with Phenoperidine.
Phenazocine The risk or severity of adverse effects can be increased when Etorphine is combined with Phenazocine.
Tilidine The risk or severity of adverse effects can be increased when Etorphine is combined with Tilidine.
Carfentanil, C-11 The risk or severity of adverse effects can be increased when Etorphine is combined with Carfentanil, C-11.
Naloxegol The risk or severity of adverse effects can be increased when Etorphine is combined with Naloxegol.
Benzhydrocodone The risk or severity of adverse effects can be increased when Etorphine is combined with Benzhydrocodone.
Pegvisomant The therapeutic efficacy of Pegvisomant can be decreased when used in combination with Etorphine.
Succinylcholine The risk or severity of bradycardia can be increased when Succinylcholine is combined with Etorphine.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Etorphine.
Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Etorphine.
Mirtazapine Etorphine may increase the serotonergic activities of Mirtazapine.
Fluvoxamine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Fluvoxamine.
Citalopram The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Citalopram.
Duloxetine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Duloxetine.
Paroxetine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Paroxetine.
Sertraline The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Sertraline.
Sibutramine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Sibutramine.
Nefazodone The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Nefazodone.
Zimelidine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Zimelidine.
Dapoxetine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Dapoxetine.
Milnacipran The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Milnacipran.
Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Etorphine.
Seproxetine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Seproxetine.
Levomilnacipran The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Levomilnacipran.
Indalpine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Indalpine.
Ritanserin The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Ritanserin.
Alaproclate The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Alaproclate.
Ethanol Etorphine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Etorphine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
Phentermine Phentermine may increase the analgesic activities of Etorphine.
Pseudoephedrine Pseudoephedrine may increase the analgesic activities of Etorphine.
Benzphetamine Benzphetamine may increase the analgesic activities of Etorphine.
Diethylpropion Diethylpropion may increase the analgesic activities of Etorphine.
Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Lisdexamfetamine.
Mephentermine Mephentermine may increase the analgesic activities of Etorphine.
MMDA MMDA may increase the analgesic activities of Etorphine.
Midomafetamine Midomafetamine may increase the analgesic activities of Etorphine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may increase the analgesic activities of Etorphine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may increase the analgesic activities of Etorphine.

Target Protein

Mu-type opioid receptor OPRM1
Delta-type opioid receptor OPRD1
Kappa-type opioid receptor OPRK1
Nociceptin receptor OPRL1
E3 ubiquitin-protein ligase TRIM13 TRIM13
Pro-opiomelanocortin POMC

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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