Dichloralphenazone

DB01495

small molecule approved illicit

Deskripsi

Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension and vascular headaches. It is a US Schedule IV drug and its clinical use is limited.

Struktur Molekul 2D

Berat 519.032
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid alcohol.

Interaksi Obat

665 Data
Buprenorphine Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Hydrocodone Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Magnesium sulfate The therapeutic efficacy of Dichloralphenazone can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Dichloralphenazone may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Mirtazapine Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Orphenadrine Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Pramipexole Dichloralphenazone may increase the sedative activities of Pramipexole.
Ropinirole Dichloralphenazone may increase the sedative activities of Ropinirole.
Rotigotine Dichloralphenazone may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Dichloralphenazone.
Suvorexant Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Thalidomide Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Dichloralphenazone.
Sodium oxybate Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Ethanol Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Dichloralphenazone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Fluvoxamine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Alaproclate.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Dichloralphenazone.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Dichloralphenazone.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with Dichloralphenazone.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with Dichloralphenazone.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with Dichloralphenazone.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Dichloralphenazone.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with Dichloralphenazone.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with Dichloralphenazone.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with Dichloralphenazone.
Pizotifen The risk or severity of CNS depression can be increased when Dichloralphenazone is combined with Pizotifen.
Dosulepin The risk or severity of CNS depression can be increased when Dichloralphenazone is combined with Dosulepin.
Zopiclone The risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Dichloralphenazone.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Dichloralphenazone.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Dichloralphenazone.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dichloralphenazone.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Dichloralphenazone.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Dichloralphenazone.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Dichloralphenazone.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Dichloralphenazone.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Dichloralphenazone.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Dichloralphenazone.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Dichloralphenazone.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Dichloralphenazone.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Dichloralphenazone.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Dichloralphenazone.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Dichloralphenazone.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Dichloralphenazone.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Dichloralphenazone.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Dichloralphenazone.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Dichloralphenazone.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Dichloralphenazone.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Dichloralphenazone.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Dichloralphenazone.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Dichloralphenazone.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Dichloralphenazone.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Dichloralphenazone.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Dichloralphenazone.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Dichloralphenazone.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Dichloralphenazone.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Dichloralphenazone.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Dichloralphenazone.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Dichloralphenazone.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Dichloralphenazone.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Dichloralphenazone.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Dichloralphenazone.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Dichloralphenazone.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Dichloralphenazone.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Dichloralphenazone.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Dichloralphenazone.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Dichloralphenazone.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Dichloralphenazone.
Sulpiride The risk or severity of CNS depression can be increased when Sulpiride is combined with Dichloralphenazone.
Alprazolam The risk or severity of CNS depression can be increased when Alprazolam is combined with Dichloralphenazone.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Dichloralphenazone.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 6106498
    Hindmarch I, Parrott AC: The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses. Arzneimittelforschung. 1980;30(6):1025-8.

Contoh Produk & Brand

Produk: 9 • International brands: 0
Produk
  • Isometheptene Mucate, Dichloralphenazone, and Acetaminophen
    Capsule • - • Oral • US
  • Isometheptene Mucate, Dichloralphenazone, and Acetaminophen
    Capsule • - • Oral • US
  • Isometheptene Mucate, Dichloralphenazone, and Acetaminophen
    Capsule, gelatin coated • - • Oral • US
  • Isometheptene Mucate/Dichloralphenazone/Acetaminophen
    Capsule • - • Oral • US
  • Isometheptene Mucate/Dichloralphenazone/Acetaminophen
    Capsule • - • Oral • US
  • Isometheptene-Dichloral-APAP Oral
    Capsule • - • Oral • US
  • Isometheptene-Dichloral-APAP Oral
    Capsule • - • Oral • US
  • LarkaDrin
    Capsule • - • Oral • US
Menampilkan 8 dari 9 produk.

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