Dimethyltryptamine

DB01488

small molecule experimental illicit

Deskripsi

An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.

Struktur Molekul 2D

Berat 188.2688
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

703 Data
Buprenorphine Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Hydrocodone Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Magnesium sulfate The therapeutic efficacy of Dimethyltryptamine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Dimethyltryptamine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Orphenadrine Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Pramipexole Dimethyltryptamine may increase the sedative activities of Pramipexole.
Ropinirole Dimethyltryptamine may increase the sedative activities of Ropinirole.
Rotigotine Dimethyltryptamine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Dimethyltryptamine.
Sodium oxybate Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Thalidomide Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Dimethyltryptamine.
Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Dimethyltryptamine.
Dicoumarol The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with (S)-Warfarin.
Mirtazapine Dimethyltryptamine may increase the serotonergic activities of Mirtazapine.
Ethanol Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Dimethyltryptamine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Zimelidine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Nefazodone.
Milnacipran The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Milnacipran.
Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Dimethyltryptamine.
Levomilnacipran The risk or severity of serotonin syndrome can be increased when Dimethyltryptamine is combined with Levomilnacipran.
Indalpine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Alaproclate.
Methylene blue Dimethyltryptamine may increase the serotonergic activities of Methylene blue.
Zopiclone The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Dimethyltryptamine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Dimethyltryptamine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dimethyltryptamine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Dimethyltryptamine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Dimethyltryptamine.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Dimethyltryptamine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Dimethyltryptamine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Dimethyltryptamine.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Dimethyltryptamine.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Dimethyltryptamine.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Dimethyltryptamine.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Dimethyltryptamine.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Dimethyltryptamine.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Dimethyltryptamine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Dimethyltryptamine.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Dimethyltryptamine.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Dimethyltryptamine.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Dimethyltryptamine.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Dimethyltryptamine.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Dimethyltryptamine.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Dimethyltryptamine.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Dimethyltryptamine.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Dimethyltryptamine.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Dimethyltryptamine.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Dimethyltryptamine.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Dimethyltryptamine.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Dimethyltryptamine.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Dimethyltryptamine.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Dimethyltryptamine.
Metocurine iodide The risk or severity of CNS depression can be increased when Metocurine iodide is combined with Dimethyltryptamine.
Secobarbital The risk or severity of CNS depression can be increased when Secobarbital is combined with Dimethyltryptamine.
Methocarbamol The risk or severity of CNS depression can be increased when Methocarbamol is combined with Dimethyltryptamine.
Triprolidine The risk or severity of CNS depression can be increased when Triprolidine is combined with Dimethyltryptamine.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Dimethyltryptamine.
Meperidine The risk or severity of CNS depression can be increased when Meperidine is combined with Dimethyltryptamine.
Metharbital The risk or severity of CNS depression can be increased when Metharbital is combined with Dimethyltryptamine.
Quinine The risk or severity of CNS depression can be increased when Quinine is combined with Dimethyltryptamine.
Methohexital The risk or severity of CNS depression can be increased when Methohexital is combined with Dimethyltryptamine.
Gallamine triethiodide The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Dimethyltryptamine.

Target Protein

5-hydroxytryptamine receptor 6 HTR6
Sigma non-opioid intracellular receptor 1 SIGMAR1
5-hydroxytryptamine receptor 2A HTR2A

Referensi & Sumber

Artikel (PubMed)
  • PMID: 8297216
    Strassman RJ, Qualls CR: Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects. Arch Gen Psychiatry. 1994 Feb;51(2):85-97.
  • PMID: 3412201
    Callaway JC: A proposed mechanism for the visions of dream sleep. Med Hypotheses. 1988 Jun;26(2):119-24.

Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

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