1-Testosterone

DB01481

small molecule experimental illicit investigational

Deskripsi

1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.

Struktur Molekul 2D

Berat 288.4244
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

149 Data
Prasterone The serum concentration of 1-Testosterone can be increased when it is combined with Prasterone.
Dextrose, unspecified form The serum concentration of Dextrose, unspecified form can be decreased when it is combined with 1-Testosterone.
Propranolol 1-Testosterone may increase the excretion rate of Propranolol which could result in a lower serum level and potentially a reduction in efficacy.
Flunisolide The risk or severity of edema formation can be increased when 1-Testosterone is combined with Flunisolide.
Beclomethasone dipropionate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Beclomethasone dipropionate.
Betamethasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Betamethasone.
Fluticasone propionate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluticasone propionate.
Fluocinolone acetonide The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluocinolone acetonide.
Triamcinolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Triamcinolone.
Prednisone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisone.
Fludrocortisone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fludrocortisone.
Hydrocortisone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Hydrocortisone.
Prednisolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisolone.
Methylprednisolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Methylprednisolone.
Trilostane The risk or severity of edema formation can be increased when 1-Testosterone is combined with Trilostane.
Budesonide The risk or severity of edema formation can be increased when 1-Testosterone is combined with Budesonide.
Dexamethasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Dexamethasone.
Corticotropin The risk or severity of edema formation can be increased when 1-Testosterone is combined with Corticotropin.
Cortisone acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Cortisone acetate.
Paramethasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Paramethasone.
Ciclesonide The risk or severity of edema formation can be increased when 1-Testosterone is combined with Ciclesonide.
Aldosterone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Aldosterone.
Fluticasone furoate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluticasone furoate.
Fluprednidene The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluprednidene.
Tixocortol The risk or severity of edema formation can be increased when 1-Testosterone is combined with Tixocortol.
Fluprednisolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluprednisolone.
Meprednisone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Meprednisone.
Dexamethasone isonicotinate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Dexamethasone isonicotinate.
Melengestrol The risk or severity of edema formation can be increased when 1-Testosterone is combined with Melengestrol.
Deflazacort The risk or severity of edema formation can be increased when 1-Testosterone is combined with Deflazacort.
Cortivazol The risk or severity of edema formation can be increased when 1-Testosterone is combined with Cortivazol.
Prednylidene The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednylidene.
Fluocortin The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluocortin.
Fluperolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluperolone.
Cloprednol The risk or severity of edema formation can be increased when 1-Testosterone is combined with Cloprednol.
Fluclorolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluclorolone.
Fluticasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluticasone.
Mometasone furoate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Mometasone furoate.
Hydrocortisone acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Hydrocortisone acetate.
Hydrocortisone cypionate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Hydrocortisone cypionate.
Hydrocortisone succinate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Hydrocortisone succinate.
Prednisolone phosphate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisolone phosphate.
Prednisolone hemisuccinate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisolone hemisuccinate.
Methylprednisolone hemisuccinate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Methylprednisolone hemisuccinate.
Prednisone acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisone acetate.
Clocortolone acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Clocortolone acetate.
Melengestrol acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Melengestrol acetate.
Betamethasone phosphate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Betamethasone phosphate.
Cortisone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Cortisone.
Clobetasol propionate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Clobetasol propionate.
Fluocinonide The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluocinonide.
Hydrocortisone butyrate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Hydrocortisone butyrate.
Desoximetasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Desoximetasone.
Mometasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Mometasone.
Fluocortolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluocortolone.
Prednisolone acetate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Prednisolone acetate.
Fluorometholone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Fluorometholone.
Difluocortolone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Difluocortolone.
Flumethasone The risk or severity of edema formation can be increased when 1-Testosterone is combined with Flumethasone.
Methylprednisolone aceponate The risk or severity of edema formation can be increased when 1-Testosterone is combined with Methylprednisolone aceponate.
Lepirudin 1-Testosterone may increase the anticoagulant activities of Lepirudin.
Bivalirudin 1-Testosterone may increase the anticoagulant activities of Bivalirudin.
Alteplase 1-Testosterone may increase the anticoagulant activities of Alteplase.
Urokinase 1-Testosterone may increase the anticoagulant activities of Urokinase.
Reteplase 1-Testosterone may increase the anticoagulant activities of Reteplase.
Anistreplase 1-Testosterone may increase the anticoagulant activities of Anistreplase.
Tenecteplase 1-Testosterone may increase the anticoagulant activities of Tenecteplase.
Abciximab 1-Testosterone may increase the anticoagulant activities of Abciximab.
Drotrecogin alfa 1-Testosterone may increase the anticoagulant activities of Drotrecogin alfa.
Streptokinase 1-Testosterone may increase the anticoagulant activities of Streptokinase.
Dicoumarol 1-Testosterone may increase the anticoagulant activities of Dicoumarol.
Argatroban 1-Testosterone may increase the anticoagulant activities of Argatroban.
Ardeparin 1-Testosterone may increase the anticoagulant activities of Ardeparin.
Phenindione 1-Testosterone may increase the anticoagulant activities of Phenindione.
Fondaparinux 1-Testosterone may increase the anticoagulant activities of Fondaparinux.
Warfarin 1-Testosterone may increase the anticoagulant activities of Warfarin.
Pentosan polysulfate 1-Testosterone may increase the anticoagulant activities of Pentosan polysulfate.
Phenprocoumon 1-Testosterone may increase the anticoagulant activities of Phenprocoumon.
Dipyridamole 1-Testosterone may increase the anticoagulant activities of Dipyridamole.
Heparin 1-Testosterone may increase the anticoagulant activities of Heparin.
Enoxaparin 1-Testosterone may increase the anticoagulant activities of Enoxaparin.
Epoprostenol 1-Testosterone may increase the anticoagulant activities of Epoprostenol.
Acenocoumarol 1-Testosterone may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin 1-Testosterone may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin 1-Testosterone may increase the anticoagulant activities of Coumarin.
Ximelagatran 1-Testosterone may increase the anticoagulant activities of Ximelagatran.
Desmoteplase 1-Testosterone may increase the anticoagulant activities of Desmoteplase.
Defibrotide 1-Testosterone may increase the anticoagulant activities of Defibrotide.
Ancrod 1-Testosterone may increase the anticoagulant activities of Ancrod.
Beraprost 1-Testosterone may increase the anticoagulant activities of Beraprost.
Prasugrel 1-Testosterone may increase the anticoagulant activities of Prasugrel.
Rivaroxaban 1-Testosterone may increase the anticoagulant activities of Rivaroxaban.
Sulodexide 1-Testosterone may increase the anticoagulant activities of Sulodexide.
Semuloparin 1-Testosterone may increase the anticoagulant activities of Semuloparin.
Idraparinux 1-Testosterone may increase the anticoagulant activities of Idraparinux.
Cangrelor 1-Testosterone may increase the anticoagulant activities of Cangrelor.
Astaxanthin 1-Testosterone may increase the anticoagulant activities of Astaxanthin.
Apixaban 1-Testosterone may increase the anticoagulant activities of Apixaban.
Otamixaban 1-Testosterone may increase the anticoagulant activities of Otamixaban.
Amediplase 1-Testosterone may increase the anticoagulant activities of Amediplase.

Target Protein

Androgen receptor AR

Referensi & Sumber

Artikel (PubMed)
  • PMID: 16621347
    Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schanzer W, Thevis M, Vollmer G, Zierau O, Diel P: 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties. Toxicol Lett. 2006 Aug 20;165(2):149-55. Epub 2006 Apr 18.

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