Antipyrine

DB01435

small molecule approved investigational

Deskripsi

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Struktur Molekul 2D

Berat 188.2258
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Take with or without food. When taken after meals, the Cmax and Tmax of oral antipyrine are reduced, but the overall bioavailability is not significantly impacted.

Interaksi Obat

1871 Data
Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Antipyrine.
Peginterferon alfa-2b The serum concentration of Antipyrine can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Antipyrine can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Antipyrine can be decreased when it is combined with Teriflunomide.
Amlodipine The metabolism of Antipyrine can be decreased when combined with Amlodipine.
Isoetharine The risk or severity of hypertension can be increased when Isoetharine is combined with Antipyrine.
Norepinephrine The risk or severity of hypertension can be increased when Norepinephrine is combined with Antipyrine.
Phenylpropanolamine The risk or severity of hypertension can be increased when Phenylpropanolamine is combined with Antipyrine.
Droperidol The risk or severity of hypertension can be increased when Droperidol is combined with Antipyrine.
Doxapram The risk or severity of hypertension can be increased when Doxapram is combined with Antipyrine.
Atropine The risk or severity of hypertension can be increased when Atropine is combined with Antipyrine.
Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Antipyrine.
Metaraminol The risk or severity of hypertension can be increased when Metaraminol is combined with Antipyrine.
Furazolidone The risk or severity of hypertension can be increased when Furazolidone is combined with Antipyrine.
Methoxamine The risk or severity of hypertension can be increased when Methoxamine is combined with Antipyrine.
Propiomazine The risk or severity of hypertension can be increased when Propiomazine is combined with Antipyrine.
Orciprenaline The risk or severity of hypertension can be increased when Orciprenaline is combined with Antipyrine.
Phenmetrazine The risk or severity of hypertension can be increased when Phenmetrazine is combined with Antipyrine.
Pseudoephedrine The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Antipyrine.
Ritodrine The risk or severity of hypertension can be increased when Ritodrine is combined with Antipyrine.
Flupentixol The risk or severity of hypertension can be increased when Flupentixol is combined with Antipyrine.
Remifentanil The risk or severity of hypertension can be increased when Remifentanil is combined with Antipyrine.
Bitolterol The risk or severity of hypertension can be increased when Bitolterol is combined with Antipyrine.
Oxymetazoline The risk or severity of hypertension can be increased when Oxymetazoline is combined with Antipyrine.
Diethylpropion The risk or severity of hypertension can be increased when Diethylpropion is combined with Antipyrine.
Naratriptan The risk or severity of hypertension can be increased when Naratriptan is combined with Antipyrine.
Isoprenaline The risk or severity of hypertension can be increased when Isoprenaline is combined with Antipyrine.
Arbutamine The risk or severity of hypertension can be increased when Arbutamine is combined with Antipyrine.
Desflurane The risk or severity of hypertension can be increased when Desflurane is combined with Antipyrine.
Isocarboxazid The risk or severity of hypertension can be increased when Isocarboxazid is combined with Antipyrine.
Fenoterol The risk or severity of hypertension can be increased when Fenoterol is combined with Antipyrine.
Pirbuterol The risk or severity of hypertension can be increased when Pirbuterol is combined with Antipyrine.
Ephedra sinica root The risk or severity of hypertension can be increased when Ephedra sinica root is combined with Antipyrine.
Ephedrine The risk or severity of hypertension can be increased when Ephedrine is combined with Antipyrine.
Mephentermine The risk or severity of hypertension can be increased when Mephentermine is combined with Antipyrine.
Procaterol The risk or severity of hypertension can be increased when Procaterol is combined with Antipyrine.
Clenbuterol The risk or severity of hypertension can be increased when Clenbuterol is combined with Antipyrine.
Bambuterol The risk or severity of hypertension can be increased when Bambuterol is combined with Antipyrine.
MMDA The risk or severity of hypertension can be increased when Antipyrine is combined with MMDA.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of hypertension can be increased when Antipyrine is combined with 2,5-Dimethoxy-4-ethylamphetamine.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of hypertension can be increased when Antipyrine is combined with 4-Bromo-2,5-dimethoxyamphetamine.
Tenamfetamine The risk or severity of hypertension can be increased when Antipyrine is combined with Tenamfetamine.
Chlorphentermine The risk or severity of hypertension can be increased when Antipyrine is combined with Chlorphentermine.
Phendimetrazine The risk or severity of hypertension can be increased when Antipyrine is combined with Phendimetrazine.
Periciazine The risk or severity of hypertension can be increased when Antipyrine is combined with Periciazine.
Acepromazine The risk or severity of hypertension can be increased when Antipyrine is combined with Acepromazine.
Thioproperazine The risk or severity of hypertension can be increased when Antipyrine is combined with Thioproperazine.
Epicaptopril The risk or severity of hypertension can be increased when Antipyrine is combined with Epicaptopril.
Clorgiline The risk or severity of hypertension can be increased when Antipyrine is combined with Clorgiline.
1-benzylimidazole The risk or severity of hypertension can be increased when Antipyrine is combined with 1-benzylimidazole.
Nialamide The risk or severity of hypertension can be increased when Antipyrine is combined with Nialamide.
Amibegron The risk or severity of hypertension can be increased when Antipyrine is combined with Amibegron.
Naluzotan The risk or severity of hypertension can be increased when Antipyrine is combined with Naluzotan.
Pizotifen The risk or severity of hypertension can be increased when Antipyrine is combined with Pizotifen.
Solabegron The risk or severity of hypertension can be increased when Antipyrine is combined with Solabegron.
Xylometazoline The risk or severity of hypertension can be increased when Antipyrine is combined with Xylometazoline.
Dexmethylphenidate The risk or severity of hypertension can be increased when Antipyrine is combined with Dexmethylphenidate.
Levonordefrin The risk or severity of hypertension can be increased when Antipyrine is combined with Levonordefrin.
Naphazoline The risk or severity of hypertension can be increased when Antipyrine is combined with Naphazoline.
Tetryzoline The risk or severity of hypertension can be increased when Antipyrine is combined with Tetryzoline.
Cinitapride The risk or severity of hypertension can be increased when Antipyrine is combined with Cinitapride.
Tyramine The risk or severity of hypertension can be increased when Antipyrine is combined with Tyramine.
Adrafinil The risk or severity of hypertension can be increased when Antipyrine is combined with Adrafinil.
Isoxsuprine The risk or severity of hypertension can be increased when Antipyrine is combined with Isoxsuprine.
Ifenprodil The risk or severity of hypertension can be increased when Antipyrine is combined with Ifenprodil.
Hexoprenaline The risk or severity of hypertension can be increased when Antipyrine is combined with Hexoprenaline.
Etilefrine The risk or severity of hypertension can be increased when Antipyrine is combined with Etilefrine.
Cirazoline The risk or severity of hypertension can be increased when Antipyrine is combined with Cirazoline.
Synephrine The risk or severity of hypertension can be increased when Antipyrine is combined with Synephrine.
Hydracarbazine The risk or severity of hypertension can be increased when Antipyrine is combined with Hydracarbazine.
Benmoxin The risk or severity of hypertension can be increased when Antipyrine is combined with Benmoxin.
Mebanazine The risk or severity of hypertension can be increased when Antipyrine is combined with Mebanazine.
Octamoxin The risk or severity of hypertension can be increased when Antipyrine is combined with Octamoxin.
Pheniprazine The risk or severity of hypertension can be increased when Antipyrine is combined with Pheniprazine.
Phenoxypropazine The risk or severity of hypertension can be increased when Antipyrine is combined with Phenoxypropazine.
Pivhydrazine The risk or severity of hypertension can be increased when Antipyrine is combined with Pivhydrazine.
Safrazine The risk or severity of hypertension can be increased when Antipyrine is combined with Safrazine.
Caroxazone The risk or severity of hypertension can be increased when Antipyrine is combined with Caroxazone.
Iofetamine I-123 The risk or severity of hypertension can be increased when Antipyrine is combined with Iofetamine I-123.
Racepinephrine The risk or severity of hypertension can be increased when Antipyrine is combined with Racepinephrine.
Amitraz The risk or severity of hypertension can be increased when Antipyrine is combined with Amitraz.
Medetomidine The risk or severity of hypertension can be increased when Antipyrine is combined with Medetomidine.
Xylazine The risk or severity of hypertension can be increased when Antipyrine is combined with Xylazine.
Atipamezole The risk or severity of hypertension can be increased when Antipyrine is combined with Atipamezole.
Ractopamine The risk or severity of hypertension can be increased when Antipyrine is combined with Ractopamine.
Romifidine The risk or severity of hypertension can be increased when Antipyrine is combined with Romifidine.
Detomidine The risk or severity of hypertension can be increased when Antipyrine is combined with Detomidine.
Tetrahydrocannabivarin The risk or severity of hypertension can be increased when Antipyrine is combined with Tetrahydrocannabivarin.
PF-00610355 The risk or severity of hypertension can be increased when Antipyrine is combined with PF-00610355.
Ritobegron The risk or severity of hypertension can be increased when Antipyrine is combined with Ritobegron.
Abediterol The risk or severity of hypertension can be increased when Antipyrine is combined with Abediterol.
Tulobuterol The risk or severity of hypertension can be increased when Antipyrine is combined with Tulobuterol.
Dopexamine The risk or severity of hypertension can be increased when Antipyrine is combined with Dopexamine.
Piclozotan The risk or severity of hypertension can be increased when Antipyrine is combined with Piclozotan.
Idazoxan The risk or severity of hypertension can be increased when Antipyrine is combined with Idazoxan.
Higenamine The risk or severity of hypertension can be increased when Antipyrine is combined with Higenamine.
Reproterol The risk or severity of hypertension can be increased when Antipyrine is combined with Reproterol.
Tramazoline The risk or severity of hypertension can be increased when Antipyrine is combined with Tramazoline.
Mephedrone The risk or severity of hypertension can be increased when Antipyrine is combined with Mephedrone.
Octopamine The risk or severity of hypertension can be increased when Antipyrine is combined with Octopamine.

Target Protein

Prostaglandin G/H synthase 1 PTGS1
Prostaglandin G/H synthase 2 PTGS2

Referensi & Sumber

Synthesis reference: Andreas Burgard, "Xanthine-and phenazone-acesulfame-H complexes having improved taste, process for their preparation and their use." U.S. Patent US20030008865, issued January 09, 2003.

Contoh Produk & Brand

Produk: 41 • International brands: 0
Produk
  • Acella Antipyrine and Benzocaine Otic
    Solution • - • Auricular (otic) • US
  • Acella Antipyrine and Benzocaine Otic
    Solution • - • Auricular (otic) • US
  • Antidouleurs Rezall
    Liquid • - • Oral • Canada • OTC • Approved
  • Antipyrine and Benzocaine
    Solution • - • Auricular (otic) • US
  • Antipyrine and Benzocaine
    Solution • - • Auricular (otic) • US
  • Antipyrine and Benzocaine
    Solution • - • Auricular (otic) • US
  • Antipyrine and Benzocaine
    Liquid • - • Topical • US
  • Antipyrine and Benzocaine
    Solution • - • Auricular (otic) • US
Menampilkan 8 dari 41 produk.

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