Can cause life-threatening agranulocytosis.
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.A254242,L43942
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Cilostazol | The serum concentration of Cilostazol can be increased when it is combined with Aminophenazone. |
| Peginterferon alfa-2b | The serum concentration of Aminophenazone can be increased when it is combined with Peginterferon alfa-2b. |
| Leflunomide | The serum concentration of Aminophenazone can be decreased when it is combined with Leflunomide. |
| Teriflunomide | The serum concentration of Aminophenazone can be decreased when it is combined with Teriflunomide. |
| Amlodipine | The metabolism of Aminophenazone can be decreased when combined with Amlodipine. |
| Isoetharine | The risk or severity of hypertension can be increased when Isoetharine is combined with Aminophenazone. |
| Norepinephrine | The risk or severity of hypertension can be increased when Norepinephrine is combined with Aminophenazone. |
| Phenylpropanolamine | The risk or severity of hypertension can be increased when Phenylpropanolamine is combined with Aminophenazone. |
| Droperidol | The risk or severity of hypertension can be increased when Droperidol is combined with Aminophenazone. |
| Doxapram | The risk or severity of hypertension can be increased when Doxapram is combined with Aminophenazone. |
| Atropine | The risk or severity of hypertension can be increased when Atropine is combined with Aminophenazone. |
| Linezolid | The risk or severity of hypertension can be increased when Linezolid is combined with Aminophenazone. |
| Metaraminol | The risk or severity of hypertension can be increased when Metaraminol is combined with Aminophenazone. |
| Furazolidone | The risk or severity of hypertension can be increased when Furazolidone is combined with Aminophenazone. |
| Methoxamine | The risk or severity of hypertension can be increased when Methoxamine is combined with Aminophenazone. |
| Isoflurane | The risk or severity of hypertension can be increased when Isoflurane is combined with Aminophenazone. |
| Propiomazine | The risk or severity of hypertension can be increased when Propiomazine is combined with Aminophenazone. |
| Orciprenaline | The risk or severity of hypertension can be increased when Orciprenaline is combined with Aminophenazone. |
| Phenmetrazine | The risk or severity of hypertension can be increased when Phenmetrazine is combined with Aminophenazone. |
| Pseudoephedrine | The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Aminophenazone. |
| Ritodrine | The risk or severity of hypertension can be increased when Ritodrine is combined with Aminophenazone. |
| Flupentixol | The risk or severity of hypertension can be increased when Flupentixol is combined with Aminophenazone. |
| Remifentanil | The risk or severity of hypertension can be increased when Remifentanil is combined with Aminophenazone. |
| Bitolterol | The risk or severity of hypertension can be increased when Bitolterol is combined with Aminophenazone. |
| Oxymetazoline | The risk or severity of hypertension can be increased when Oxymetazoline is combined with Aminophenazone. |
| Diethylpropion | The risk or severity of hypertension can be increased when Diethylpropion is combined with Aminophenazone. |
| Naratriptan | The risk or severity of hypertension can be increased when Naratriptan is combined with Aminophenazone. |
| Isoprenaline | The risk or severity of hypertension can be increased when Isoprenaline is combined with Aminophenazone. |
| Arbutamine | The risk or severity of hypertension can be increased when Arbutamine is combined with Aminophenazone. |
| Desflurane | The risk or severity of hypertension can be increased when Desflurane is combined with Aminophenazone. |
| Isocarboxazid | The risk or severity of hypertension can be increased when Isocarboxazid is combined with Aminophenazone. |
| Lisdexamfetamine | The risk or severity of hypertension can be increased when Lisdexamfetamine is combined with Aminophenazone. |
| Fenoterol | The risk or severity of hypertension can be increased when Fenoterol is combined with Aminophenazone. |
| Pirbuterol | The risk or severity of hypertension can be increased when Pirbuterol is combined with Aminophenazone. |
| Ephedra sinica root | The risk or severity of hypertension can be increased when Ephedra sinica root is combined with Aminophenazone. |
| Ephedrine | The risk or severity of hypertension can be increased when Ephedrine is combined with Aminophenazone. |
| Mephentermine | The risk or severity of hypertension can be increased when Mephentermine is combined with Aminophenazone. |
| Procaterol | The risk or severity of hypertension can be increased when Procaterol is combined with Aminophenazone. |
| Clenbuterol | The risk or severity of hypertension can be increased when Clenbuterol is combined with Aminophenazone. |
| Bambuterol | The risk or severity of hypertension can be increased when Bambuterol is combined with Aminophenazone. |
| MMDA | The risk or severity of hypertension can be increased when Aminophenazone is combined with MMDA. |
| 2,5-Dimethoxy-4-ethylamphetamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with 2,5-Dimethoxy-4-ethylamphetamine. |
| 4-Bromo-2,5-dimethoxyamphetamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with 4-Bromo-2,5-dimethoxyamphetamine. |
| Tenamfetamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Tenamfetamine. |
| Chlorphentermine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Chlorphentermine. |
| Dextroamphetamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Dextroamphetamine. |
| Phendimetrazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Phendimetrazine. |
| Periciazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Periciazine. |
| Acepromazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Acepromazine. |
| Thioproperazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Thioproperazine. |
| Epicaptopril | The risk or severity of hypertension can be increased when Aminophenazone is combined with Epicaptopril. |
| Clorgiline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Clorgiline. |
| 1-benzylimidazole | The risk or severity of hypertension can be increased when Aminophenazone is combined with 1-benzylimidazole. |
| Nialamide | The risk or severity of hypertension can be increased when Aminophenazone is combined with Nialamide. |
| Amibegron | The risk or severity of hypertension can be increased when Aminophenazone is combined with Amibegron. |
| Naluzotan | The risk or severity of hypertension can be increased when Aminophenazone is combined with Naluzotan. |
| Pizotifen | The risk or severity of hypertension can be increased when Aminophenazone is combined with Pizotifen. |
| Solabegron | The risk or severity of hypertension can be increased when Aminophenazone is combined with Solabegron. |
| Nitrous oxide | The risk or severity of hypertension can be increased when Aminophenazone is combined with Nitrous oxide. |
| Xylometazoline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Xylometazoline. |
| Dexmethylphenidate | The risk or severity of hypertension can be increased when Aminophenazone is combined with Dexmethylphenidate. |
| Isometheptene | The risk or severity of hypertension can be increased when Aminophenazone is combined with Isometheptene. |
| Levonordefrin | The risk or severity of hypertension can be increased when Aminophenazone is combined with Levonordefrin. |
| Naphazoline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Naphazoline. |
| Tetryzoline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Tetryzoline. |
| Cinitapride | The risk or severity of hypertension can be increased when Aminophenazone is combined with Cinitapride. |
| Tyramine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Tyramine. |
| Adrafinil | The risk or severity of hypertension can be increased when Aminophenazone is combined with Adrafinil. |
| Isoxsuprine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Isoxsuprine. |
| Ifenprodil | The risk or severity of hypertension can be increased when Aminophenazone is combined with Ifenprodil. |
| Hexoprenaline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Hexoprenaline. |
| Etilefrine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Etilefrine. |
| Cirazoline | The risk or severity of hypertension can be increased when Aminophenazone is combined with Cirazoline. |
| Synephrine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Synephrine. |
| Hydracarbazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Hydracarbazine. |
| Benmoxin | The risk or severity of hypertension can be increased when Aminophenazone is combined with Benmoxin. |
| Mebanazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Mebanazine. |
| Octamoxin | The risk or severity of hypertension can be increased when Aminophenazone is combined with Octamoxin. |
| Pheniprazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Pheniprazine. |
| Phenoxypropazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Phenoxypropazine. |
| Pivhydrazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Pivhydrazine. |
| Safrazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Safrazine. |
| Caroxazone | The risk or severity of hypertension can be increased when Aminophenazone is combined with Caroxazone. |
| Iofetamine I-123 | The risk or severity of hypertension can be increased when Aminophenazone is combined with Iofetamine I-123. |
| Racepinephrine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Racepinephrine. |
| Amitraz | The risk or severity of hypertension can be increased when Aminophenazone is combined with Amitraz. |
| Medetomidine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Medetomidine. |
| Xylazine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Xylazine. |
| Atipamezole | The risk or severity of hypertension can be increased when Aminophenazone is combined with Atipamezole. |
| Ractopamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Ractopamine. |
| Romifidine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Romifidine. |
| Detomidine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Detomidine. |
| Tetrahydrocannabivarin | The risk or severity of hypertension can be increased when Aminophenazone is combined with Tetrahydrocannabivarin. |
| PF-00610355 | The risk or severity of hypertension can be increased when Aminophenazone is combined with PF-00610355. |
| Ritobegron | The risk or severity of hypertension can be increased when Aminophenazone is combined with Ritobegron. |
| Abediterol | The risk or severity of hypertension can be increased when Aminophenazone is combined with Abediterol. |
| Tulobuterol | The risk or severity of hypertension can be increased when Aminophenazone is combined with Tulobuterol. |
| Dopexamine | The risk or severity of hypertension can be increased when Aminophenazone is combined with Dopexamine. |
| Piclozotan | The risk or severity of hypertension can be increased when Aminophenazone is combined with Piclozotan. |
| Idazoxan | The risk or severity of hypertension can be increased when Aminophenazone is combined with Idazoxan. |