Bambuterol

DB01408

small molecule investigational

Deskripsi

Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

Struktur Molekul 2D

Berat 367.44
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 13 hours for bambuterol and 21 hours for the primary active metabolite terbutaline.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Bioavailability is 20% following oral administration.

Metabolisme

Hepatic, extensive. Further metabolized to terbutaline by plasma cholinesterase.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

896 Data
Loxapine The therapeutic efficacy of Bambuterol can be decreased when used in combination with Loxapine.
Valsartan Bambuterol may decrease the antihypertensive activities of Valsartan.
Reserpine Bambuterol may decrease the antihypertensive activities of Reserpine.
Remikiren Bambuterol may decrease the antihypertensive activities of Remikiren.
Isradipine Bambuterol may decrease the antihypertensive activities of Isradipine.
Olmesartan Bambuterol may decrease the antihypertensive activities of Olmesartan.
Nitroprusside Bambuterol may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Bambuterol may decrease the antihypertensive activities of Diltiazem.
Minoxidil Bambuterol may decrease the antihypertensive activities of Minoxidil.
Treprostinil Bambuterol may decrease the antihypertensive activities of Treprostinil.
Amlodipine Bambuterol may decrease the antihypertensive activities of Amlodipine.
Nimodipine Bambuterol may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Bambuterol may decrease the antihypertensive activities of Nisoldipine.
Fosinopril Bambuterol may decrease the antihypertensive activities of Fosinopril.
Trandolapril Bambuterol may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Bambuterol may decrease the antihypertensive activities of Lercanidipine.
Benazepril Bambuterol may decrease the antihypertensive activities of Benazepril.
Bosentan Bambuterol may decrease the antihypertensive activities of Bosentan.
Enalapril Bambuterol may decrease the antihypertensive activities of Enalapril.
Candoxatril Bambuterol may decrease the antihypertensive activities of Candoxatril.
Losartan Bambuterol may decrease the antihypertensive activities of Losartan.
Moexipril Bambuterol may decrease the antihypertensive activities of Moexipril.
Eplerenone Bambuterol may decrease the antihypertensive activities of Eplerenone.
Lisinopril Bambuterol may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Bambuterol may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Bambuterol may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Bambuterol may decrease the antihypertensive activities of Cryptenamine.
Candesartan cilexetil Bambuterol may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Bambuterol may decrease the antihypertensive activities of Fenoldopam.
Tadalafil Bambuterol may decrease the antihypertensive activities of Tadalafil.
Eprosartan Bambuterol may decrease the antihypertensive activities of Eprosartan.
Quinapril Bambuterol may decrease the antihypertensive activities of Quinapril.
Telmisartan Bambuterol may decrease the antihypertensive activities of Telmisartan.
Methyldopa Bambuterol may decrease the antihypertensive activities of Methyldopa.
Irbesartan Bambuterol may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Bambuterol may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Bambuterol may decrease the antihypertensive activities of Deserpidine.
Diazoxide Bambuterol may decrease the antihypertensive activities of Diazoxide.
Captopril Bambuterol may decrease the antihypertensive activities of Captopril.
Epoprostenol Bambuterol may decrease the antihypertensive activities of Epoprostenol.
Bepridil Bambuterol may decrease the antihypertensive activities of Bepridil.
Hydralazine Bambuterol may decrease the antihypertensive activities of Hydralazine.
Cilazapril Bambuterol may decrease the antihypertensive activities of Cilazapril.
Saprisartan Bambuterol may decrease the antihypertensive activities of Saprisartan.
Spirapril Bambuterol may decrease the antihypertensive activities of Spirapril.
Mibefradil Bambuterol may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Bambuterol may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Bambuterol may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Bambuterol may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Bambuterol may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Bambuterol may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Bambuterol may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Bambuterol may decrease the antihypertensive activities of Pinacidil.
Temocapril Bambuterol may decrease the antihypertensive activities of Temocapril.
Riociguat Bambuterol may decrease the antihypertensive activities of Riociguat.
Macitentan Bambuterol may decrease the antihypertensive activities of Macitentan.
Aliskiren Bambuterol may decrease the antihypertensive activities of Aliskiren.
Nicorandil Bambuterol may decrease the antihypertensive activities of Nicorandil.
Efonidipine Bambuterol may decrease the antihypertensive activities of Efonidipine.
Lacidipine Bambuterol may decrease the antihypertensive activities of Lacidipine.
Manidipine Bambuterol may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Bambuterol may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Bambuterol may decrease the antihypertensive activities of Enalaprilat.
Selexipag Bambuterol may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Bambuterol may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Bambuterol may decrease the antihypertensive activities of Imidapril.
BQ-123 Bambuterol may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Bambuterol may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Bambuterol may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Bambuterol may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Bambuterol may decrease the antihypertensive activities of Zofenopril.
Guanoxan Bambuterol may decrease the antihypertensive activities of Guanoxan.
Delapril Bambuterol may decrease the antihypertensive activities of Delapril.
Vincamine Bambuterol may decrease the antihypertensive activities of Vincamine.
Linsidomine Bambuterol may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Bambuterol may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Bambuterol may decrease the antihypertensive activities of Tolonidine.
Endralazine Bambuterol may decrease the antihypertensive activities of Endralazine.
Cadralazine Bambuterol may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Bambuterol may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Bambuterol may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Bambuterol may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Bambuterol may decrease the antihypertensive activities of Guanoclor.
Muzolimine Bambuterol may decrease the antihypertensive activities of Muzolimine.
Xipamide Bambuterol may decrease the antihypertensive activities of Xipamide.
Candesartan Bambuterol may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Bambuterol may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Bambuterol may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Bambuterol may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Bambuterol may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Bambuterol may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Bambuterol may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Bambuterol may decrease the antihypertensive activities of Quinaprilat.
Felodipine Bambuterol may decrease the antihypertensive activities of Felodipine.
Ramipril Bambuterol may decrease the antihypertensive activities of Ramipril.
Perindopril Bambuterol may decrease the antihypertensive activities of Perindopril.
Levamlodipine Bambuterol may decrease the antihypertensive activities of Levamlodipine.
Azilsartan medoxomil Bambuterol may decrease the antihypertensive activities of Azilsartan medoxomil.
Succinylcholine The therapeutic efficacy of Succinylcholine can be increased when used in combination with Bambuterol.
Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Bambuterol.

Target Protein

Beta-2 adrenergic receptor ADRB2
Cholinesterase BCHE

Referensi & Sumber

Synthesis reference: Peter Jaksch, "Method of preparing an intermediate for the manufacture of bambuterol." U.S. Patent US5200551, issued May, 1986.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Bambec
  • Oxeol

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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