Salicylate intoxication, known as salicylism, may occur with large doses or extended therapy. Common symptoms of salicylism include headache, dizziness, tinnitus, hearing impairment, confusion, drowsiness, sweating, vomiting, diarrhea, and hyperventilation. A more severe degree of salicylate intoxication can lead to CNS disturbances, alteration in electrolyte balance, respiratory and metabolic acidosis, hyperthermia, and dehydration.
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% A19653, A19654.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Amlodipine | Choline magnesium trisalicylate may decrease the antihypertensive activities of Amlodipine. |
| Phentermine | The risk or severity of hypertension can be increased when Phentermine is combined with Choline magnesium trisalicylate. |
| Midodrine | The risk or severity of hypertension can be increased when Midodrine is combined with Choline magnesium trisalicylate. |
| Eletriptan | The risk or severity of hypertension can be increased when Eletriptan is combined with Choline magnesium trisalicylate. |
| Isoetharine | The risk or severity of hypertension can be increased when Isoetharine is combined with Choline magnesium trisalicylate. |
| Ziprasidone | The risk or severity of hypertension can be increased when Ziprasidone is combined with Choline magnesium trisalicylate. |
| Methysergide | The risk or severity of hypertension can be increased when Methysergide is combined with Choline magnesium trisalicylate. |
| Cabergoline | The risk or severity of hypertension can be increased when Cabergoline is combined with Choline magnesium trisalicylate. |
| Zolmitriptan | The risk or severity of hypertension can be increased when Zolmitriptan is combined with Choline magnesium trisalicylate. |
| Dihydroergotamine | The risk or severity of hypertension can be increased when Dihydroergotamine is combined with Choline magnesium trisalicylate. |
| Methylergometrine | The risk or severity of hypertension can be increased when Methylergometrine is combined with Choline magnesium trisalicylate. |
| Norepinephrine | The risk or severity of hypertension can be increased when Norepinephrine is combined with Choline magnesium trisalicylate. |
| Mirtazapine | The risk or severity of hypertension can be increased when Mirtazapine is combined with Choline magnesium trisalicylate. |
| Phenylephrine | The risk or severity of hypertension can be increased when Phenylephrine is combined with Choline magnesium trisalicylate. |
| Phenylpropanolamine | The risk or severity of hypertension can be increased when Phenylpropanolamine is combined with Choline magnesium trisalicylate. |
| Promazine | The risk or severity of hypertension can be increased when Promazine is combined with Choline magnesium trisalicylate. |
| Droperidol | The risk or severity of hypertension can be increased when Droperidol is combined with Choline magnesium trisalicylate. |
| Doxapram | The risk or severity of hypertension can be increased when Doxapram is combined with Choline magnesium trisalicylate. |
| Atropine | The risk or severity of hypertension can be increased when Atropine is combined with Choline magnesium trisalicylate. |
| Lisuride | The risk or severity of hypertension can be increased when Lisuride is combined with Choline magnesium trisalicylate. |
| Linezolid | The risk or severity of hypertension can be increased when Linezolid is combined with Choline magnesium trisalicylate. |
| Metaraminol | The risk or severity of hypertension can be increased when Metaraminol is combined with Choline magnesium trisalicylate. |
| Furazolidone | The risk or severity of hypertension can be increased when Furazolidone is combined with Choline magnesium trisalicylate. |
| Epinephrine | The risk or severity of hypertension can be increased when Epinephrine is combined with Choline magnesium trisalicylate. |
| Thioridazine | The risk or severity of hypertension can be increased when Thioridazine is combined with Choline magnesium trisalicylate. |
| Ergotamine | The risk or severity of hypertension can be increased when Ergotamine is combined with Choline magnesium trisalicylate. |
| Nicergoline | The risk or severity of hypertension can be increased when Nicergoline is combined with Choline magnesium trisalicylate. |
| Sufentanil | The risk or severity of hypertension can be increased when Sufentanil is combined with Choline magnesium trisalicylate. |
| Methoxamine | The risk or severity of hypertension can be increased when Methoxamine is combined with Choline magnesium trisalicylate. |
| Risperidone | The risk or severity of hypertension can be increased when Risperidone is combined with Choline magnesium trisalicylate. |
| Tranylcypromine | The risk or severity of hypertension can be increased when Tranylcypromine is combined with Choline magnesium trisalicylate. |
| Isoflurane | The risk or severity of hypertension can be increased when Isoflurane is combined with Choline magnesium trisalicylate. |
| Propiomazine | The risk or severity of hypertension can be increased when Propiomazine is combined with Choline magnesium trisalicylate. |
| Alfentanil | The risk or severity of hypertension can be increased when Alfentanil is combined with Choline magnesium trisalicylate. |
| Minaprine | The risk or severity of hypertension can be increased when Minaprine is combined with Choline magnesium trisalicylate. |
| Orciprenaline | The risk or severity of hypertension can be increased when Orciprenaline is combined with Choline magnesium trisalicylate. |
| Propofol | The risk or severity of hypertension can be increased when Propofol is combined with Choline magnesium trisalicylate. |
| Phenmetrazine | The risk or severity of hypertension can be increased when Phenmetrazine is combined with Choline magnesium trisalicylate. |
| Trifluoperazine | The risk or severity of hypertension can be increased when Trifluoperazine is combined with Choline magnesium trisalicylate. |
| Pseudoephedrine | The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Choline magnesium trisalicylate. |
| Benzphetamine | The risk or severity of hypertension can be increased when Benzphetamine is combined with Choline magnesium trisalicylate. |
| Ritodrine | The risk or severity of hypertension can be increased when Ritodrine is combined with Choline magnesium trisalicylate. |
| Flupentixol | The risk or severity of hypertension can be increased when Flupentixol is combined with Choline magnesium trisalicylate. |
| Remifentanil | The risk or severity of hypertension can be increased when Remifentanil is combined with Choline magnesium trisalicylate. |
| Bitolterol | The risk or severity of hypertension can be increased when Bitolterol is combined with Choline magnesium trisalicylate. |
| Oxymetazoline | The risk or severity of hypertension can be increased when Oxymetazoline is combined with Choline magnesium trisalicylate. |
| Diethylpropion | The risk or severity of hypertension can be increased when Diethylpropion is combined with Choline magnesium trisalicylate. |
| Salmeterol | The risk or severity of hypertension can be increased when Salmeterol is combined with Choline magnesium trisalicylate. |
| Naratriptan | The risk or severity of hypertension can be increased when Naratriptan is combined with Choline magnesium trisalicylate. |
| Formoterol | The risk or severity of hypertension can be increased when Formoterol is combined with Choline magnesium trisalicylate. |
| Frovatriptan | The risk or severity of hypertension can be increased when Frovatriptan is combined with Choline magnesium trisalicylate. |
| Methoxyflurane | The risk or severity of hypertension can be increased when Methoxyflurane is combined with Choline magnesium trisalicylate. |
| Selegiline | The risk or severity of hypertension can be increased when Selegiline is combined with Choline magnesium trisalicylate. |
| Ergoloid mesylate | The risk or severity of hypertension can be increased when Ergoloid mesylate is combined with Choline magnesium trisalicylate. |
| Isoprenaline | The risk or severity of hypertension can be increased when Isoprenaline is combined with Choline magnesium trisalicylate. |
| Arbutamine | The risk or severity of hypertension can be increased when Arbutamine is combined with Choline magnesium trisalicylate. |
| Dutasteride | The risk or severity of hypertension can be increased when Dutasteride is combined with Choline magnesium trisalicylate. |
| Halothane | The risk or severity of hypertension can be increased when Halothane is combined with Choline magnesium trisalicylate. |
| Moclobemide | The risk or severity of hypertension can be increased when Moclobemide is combined with Choline magnesium trisalicylate. |
| Pergolide | The risk or severity of hypertension can be increased when Pergolide is combined with Choline magnesium trisalicylate. |
| Desflurane | The risk or severity of hypertension can be increased when Desflurane is combined with Choline magnesium trisalicylate. |
| Bromocriptine | The risk or severity of hypertension can be increased when Bromocriptine is combined with Choline magnesium trisalicylate. |
| Finasteride | The risk or severity of hypertension can be increased when Finasteride is combined with Choline magnesium trisalicylate. |
| Aripiprazole | The risk or severity of hypertension can be increased when Aripiprazole is combined with Choline magnesium trisalicylate. |
| Isocarboxazid | The risk or severity of hypertension can be increased when Isocarboxazid is combined with Choline magnesium trisalicylate. |
| Ergometrine | The risk or severity of hypertension can be increased when Ergometrine is combined with Choline magnesium trisalicylate. |
| Lisdexamfetamine | The risk or severity of hypertension can be increased when Lisdexamfetamine is combined with Choline magnesium trisalicylate. |
| Fenoterol | The risk or severity of hypertension can be increased when Fenoterol is combined with Choline magnesium trisalicylate. |
| Pirbuterol | The risk or severity of hypertension can be increased when Pirbuterol is combined with Choline magnesium trisalicylate. |
| Ephedra sinica root | The risk or severity of hypertension can be increased when Ephedra sinica root is combined with Choline magnesium trisalicylate. |
| Ephedrine | The risk or severity of hypertension can be increased when Ephedrine is combined with Choline magnesium trisalicylate. |
| Mephentermine | The risk or severity of hypertension can be increased when Mephentermine is combined with Choline magnesium trisalicylate. |
| Procaterol | The risk or severity of hypertension can be increased when Procaterol is combined with Choline magnesium trisalicylate. |
| Yohimbine | The risk or severity of hypertension can be increased when Yohimbine is combined with Choline magnesium trisalicylate. |
| Methotrimeprazine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Methotrimeprazine. |
| Clenbuterol | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Clenbuterol. |
| Bambuterol | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Bambuterol. |
| MMDA | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with MMDA. |
| Midomafetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Midomafetamine. |
| 2,5-Dimethoxy-4-ethylamphetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with 2,5-Dimethoxy-4-ethylamphetamine. |
| 4-Methoxyamphetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with 4-Methoxyamphetamine. |
| 4-Bromo-2,5-dimethoxyamphetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with 4-Bromo-2,5-dimethoxyamphetamine. |
| Tenamfetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Tenamfetamine. |
| Chlorphentermine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Chlorphentermine. |
| Dextroamphetamine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Dextroamphetamine. |
| Phendimetrazine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Phendimetrazine. |
| Solifenacin | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Solifenacin. |
| Periciazine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Periciazine. |
| Acepromazine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Acepromazine. |
| Thioproperazine | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Thioproperazine. |
| Zuclopenthixol | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Zuclopenthixol. |
| Epicaptopril | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Epicaptopril. |
| Clorgiline | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Clorgiline. |
| 1-benzylimidazole | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with 1-benzylimidazole. |
| Iproniazid | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Iproniazid. |
| Nialamide | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Nialamide. |
| Lysergic acid diethylamide | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Lysergic acid diethylamide. |
| Dronedarone | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Dronedarone. |
| Flibanserin | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Flibanserin. |
| Iloperidone | The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Iloperidone. |