Ephedra sinica root

DB01363

biotech nutraceutical

Deskripsi

Ephedra is an alkaloid chemical compound traditionally obtained from the plant Ephedra sinica. The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for clinical effectiveness. The drug is still sold in Canada in OTC formulations for respiratory conditions associated with bronchial asthma.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

886 Data
Valsartan Ephedra sinica root may decrease the antihypertensive activities of Valsartan.
Ramipril Ephedra sinica root may decrease the antihypertensive activities of Ramipril.
Reserpine Ephedra sinica root may decrease the antihypertensive activities of Reserpine.
Remikiren Ephedra sinica root may decrease the antihypertensive activities of Remikiren.
Isradipine Ephedra sinica root may decrease the antihypertensive activities of Isradipine.
Olmesartan Ephedra sinica root may decrease the antihypertensive activities of Olmesartan.
Nitroprusside Ephedra sinica root may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Ephedra sinica root may decrease the antihypertensive activities of Diltiazem.
Minoxidil Ephedra sinica root may decrease the antihypertensive activities of Minoxidil.
Treprostinil Ephedra sinica root may decrease the antihypertensive activities of Treprostinil.
Amlodipine Ephedra sinica root may decrease the antihypertensive activities of Amlodipine.
Nimodipine Ephedra sinica root may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Ephedra sinica root may decrease the antihypertensive activities of Nisoldipine.
Fosinopril Ephedra sinica root may decrease the antihypertensive activities of Fosinopril.
Trandolapril Ephedra sinica root may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Ephedra sinica root may decrease the antihypertensive activities of Lercanidipine.
Benazepril Ephedra sinica root may decrease the antihypertensive activities of Benazepril.
Bosentan Ephedra sinica root may decrease the antihypertensive activities of Bosentan.
Enalapril Ephedra sinica root may decrease the antihypertensive activities of Enalapril.
Candoxatril Ephedra sinica root may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Ephedra sinica root may decrease the antihypertensive activities of Mecamylamine.
Losartan Ephedra sinica root may decrease the antihypertensive activities of Losartan.
Moexipril Ephedra sinica root may decrease the antihypertensive activities of Moexipril.
Eplerenone Ephedra sinica root may decrease the antihypertensive activities of Eplerenone.
Lisinopril Ephedra sinica root may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Ephedra sinica root may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Ephedra sinica root may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Ephedra sinica root may decrease the antihypertensive activities of Cryptenamine.
Perindopril Ephedra sinica root may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Ephedra sinica root may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Ephedra sinica root may decrease the antihypertensive activities of Fenoldopam.
Tadalafil Ephedra sinica root may decrease the antihypertensive activities of Tadalafil.
Eprosartan Ephedra sinica root may decrease the antihypertensive activities of Eprosartan.
Quinapril Ephedra sinica root may decrease the antihypertensive activities of Quinapril.
Telmisartan Ephedra sinica root may decrease the antihypertensive activities of Telmisartan.
Methyldopa Ephedra sinica root may decrease the antihypertensive activities of Methyldopa.
Irbesartan Ephedra sinica root may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Ephedra sinica root may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Ephedra sinica root may decrease the antihypertensive activities of Deserpidine.
Pentolinium Ephedra sinica root may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Ephedra sinica root may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Ephedra sinica root may decrease the antihypertensive activities of Diazoxide.
Captopril Ephedra sinica root may decrease the antihypertensive activities of Captopril.
Epoprostenol Ephedra sinica root may decrease the antihypertensive activities of Epoprostenol.
Bepridil Ephedra sinica root may decrease the antihypertensive activities of Bepridil.
Hydralazine Ephedra sinica root may decrease the antihypertensive activities of Hydralazine.
Cilazapril Ephedra sinica root may decrease the antihypertensive activities of Cilazapril.
Saprisartan Ephedra sinica root may decrease the antihypertensive activities of Saprisartan.
Spirapril Ephedra sinica root may decrease the antihypertensive activities of Spirapril.
Mibefradil Ephedra sinica root may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Ephedra sinica root may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Ephedra sinica root may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Ephedra sinica root may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Ephedra sinica root may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Ephedra sinica root may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Ephedra sinica root may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Ephedra sinica root may decrease the antihypertensive activities of Pinacidil.
Temocapril Ephedra sinica root may decrease the antihypertensive activities of Temocapril.
Riociguat Ephedra sinica root may decrease the antihypertensive activities of Riociguat.
Macitentan Ephedra sinica root may decrease the antihypertensive activities of Macitentan.
Hexamethonium Ephedra sinica root may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Ephedra sinica root may decrease the antihypertensive activities of Aliskiren.
Nicorandil Ephedra sinica root may decrease the antihypertensive activities of Nicorandil.
Efonidipine Ephedra sinica root may decrease the antihypertensive activities of Efonidipine.
Lacidipine Ephedra sinica root may decrease the antihypertensive activities of Lacidipine.
Manidipine Ephedra sinica root may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Ephedra sinica root may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Ephedra sinica root may decrease the antihypertensive activities of Enalaprilat.
Selexipag Ephedra sinica root may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Ephedra sinica root may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Ephedra sinica root may decrease the antihypertensive activities of Imidapril.
BQ-123 Ephedra sinica root may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Ephedra sinica root may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Ephedra sinica root may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Ephedra sinica root may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Ephedra sinica root may decrease the antihypertensive activities of Zofenopril.
Guanoxan Ephedra sinica root may decrease the antihypertensive activities of Guanoxan.
Delapril Ephedra sinica root may decrease the antihypertensive activities of Delapril.
Vincamine Ephedra sinica root may decrease the antihypertensive activities of Vincamine.
Linsidomine Ephedra sinica root may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Ephedra sinica root may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Ephedra sinica root may decrease the antihypertensive activities of Tolonidine.
Endralazine Ephedra sinica root may decrease the antihypertensive activities of Endralazine.
Cadralazine Ephedra sinica root may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Ephedra sinica root may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Ephedra sinica root may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Ephedra sinica root may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Ephedra sinica root may decrease the antihypertensive activities of Guanoclor.
Muzolimine Ephedra sinica root may decrease the antihypertensive activities of Muzolimine.
Xipamide Ephedra sinica root may decrease the antihypertensive activities of Xipamide.
Candesartan Ephedra sinica root may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Ephedra sinica root may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Ephedra sinica root may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Ephedra sinica root may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Ephedra sinica root may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Ephedra sinica root may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Ephedra sinica root may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Ephedra sinica root may decrease the antihypertensive activities of Quinaprilat.
Felodipine Ephedra sinica root may decrease the antihypertensive activities of Felodipine.
Levamlodipine Ephedra sinica root may decrease the antihypertensive activities of Levamlodipine.

Target Protein

Sodium-dependent dopamine transporter SLC6A3
Sodium-dependent noradrenaline transporter SLC6A2
Alpha-2A adrenergic receptor ADRA2A
Alpha-2B adrenergic receptor ADRA2B
Alpha-2C adrenergic receptor ADRA2C
Amine oxidase [flavin-containing] A MAOA
Amine oxidase [flavin-containing] B MAOB
Beta-1 adrenergic receptor ADRB1
Beta-2 adrenergic receptor ADRB2
Beta-3 adrenergic receptor ADRB3
Sodium-dependent serotonin transporter SLC6A4
Synaptic vesicular amine transporter SLC18A2
Chromaffin granule amine transporter SLC18A1

Referensi & Sumber

Artikel (PubMed)
  • PMID: 10189265
    Gurley BJ, Wang P, Gardner SF: Ephedrine-type alkaloid content of nutritional supplements containing Ephedra sinica (Ma-huang) as determined by high performance liquid chromatography. J Pharm Sci. 1998 Dec;87(12):1547-53.
  • PMID: 12916063
    Abourashed EA, El-Alfy AT, Khan IA, Walker L: Ephedra in perspective--a current review. Phytother Res. 2003 Aug;17(7):703-12.
  • PMID: 11117974
    Haller CA, Benowitz NL: Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med. 2000 Dec 21;343(25):1833-8.
  • PMID: 12639079
    Bent S, Tiedt TN, Odden MC, Shlipak MG: The relative safety of ephedra compared with other herbal products. Ann Intern Med. 2003 Mar 18;138(6):468-71.

Contoh Produk & Brand

Produk: 26 • International brands: 1
Produk
  • Citrivate
    Capsule • 84 mg • Oral • Canada • OTC • Approved
  • Decongestionnant - Cap Orl
    Capsule • 250 mg / cap • Oral • Canada • OTC • Approved
  • Dp Formula
    Tablet • 107 mg • Oral • Canada • OTC • Approved
  • Dp Formula - 133mg Tab
    Tablet • 133 mg • Oral • Canada • OTC • Approved
  • Dr. Miller's Formula No. 1
    Tablet • - • Oral • Canada • OTC • Approved
  • Ephedra
    Capsule • 300 mg / cap • Oral • Canada • OTC • Approved
  • Ephedra - Cap 300mg
    Capsule • 300 mg / cap • Oral • Canada • OTC • Approved
  • Ephedra -tab 100mg
    Tablet • 100 mg • Oral • Canada • OTC • Approved
Menampilkan 8 dari 26 produk.
International Brands
  • Sinueaze

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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