Peringatan Keamanan

Symptoms of an overdose typically include sluggishness, incoordination, difficulty in thinking, slowness of speech, faulty judgment, drowsiness or coma, shallow breathing, staggering, and in severe cases coma and death.

Hexobarbital

DB01355

small molecule experimental

Deskripsi

A barbiturate that is effective as a hypnotic and sedative.

Struktur Molekul 2D

Berat 236.267
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1461 Data
Buprenorphine Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Hydrocodone Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Magnesium sulfate The therapeutic efficacy of Hexobarbital can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Hexobarbital may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Mirtazapine Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Orphenadrine Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Pramipexole Hexobarbital may increase the sedative activities of Pramipexole.
Ropinirole Hexobarbital may increase the sedative activities of Ropinirole.
Rotigotine Hexobarbital may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Hexobarbital.
Suvorexant Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Thalidomide Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Dabrafenib The serum concentration of Hexobarbital can be decreased when it is combined with Dabrafenib.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Hexobarbital.
Luliconazole The serum concentration of Hexobarbital can be increased when it is combined with Luliconazole.
Mefloquine The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Mefloquine.
Orlistat Orlistat can cause a decrease in the absorption of Hexobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy.
Acetaminophen The metabolism of Acetaminophen can be increased when combined with Hexobarbital.
Propacetamol The metabolism of Propacetamol can be increased when combined with Hexobarbital.
Chloramphenicol The metabolism of Hexobarbital can be decreased when combined with Chloramphenicol.
Doxycycline The serum concentration of Doxycycline can be decreased when it is combined with Hexobarbital.
Felbamate The serum concentration of Hexobarbital can be increased when it is combined with Felbamate.
Griseofulvin The serum concentration of Griseofulvin can be decreased when it is combined with Hexobarbital.
Lamotrigine The serum concentration of Lamotrigine can be decreased when it is combined with Hexobarbital.
Mianserin The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Mianserin.
Methylphenobarbital The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Hexobarbital.
Pyridoxine The metabolism of Hexobarbital can be increased when combined with Pyridoxine.
Teniposide The serum concentration of Teniposide can be decreased when it is combined with Hexobarbital.
Ulipristal The serum concentration of Ulipristal can be decreased when it is combined with Hexobarbital.
Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with Hexobarbital.
Topotecan Hexobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Hexobarbital.
Sodium oxybate Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Tetracosactide The risk or severity of liver damage can be increased when Tetracosactide is combined with Hexobarbital.
Aminophylline The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Aminophylline.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Hexobarbital is combined with Botulinum toxin type A.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Hexobarbital is combined with Botulinum toxin type B.
Meperidine Hexobarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine.
Somatostatin The risk or severity of adverse effects can be increased when Somatostatin is combined with Hexobarbital.
Ethanol Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Hexobarbital may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
Citalopram The risk or severity of adverse effects can be increased when Hexobarbital is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Hexobarbital is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Sibutramine.
Escitalopram The risk or severity of adverse effects can be increased when Hexobarbital is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dapoxetine.
Desvenlafaxine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Hexobarbital is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Hexobarbital is combined with Alaproclate.
Nefazodone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Nefazodone.
Milnacipran The risk or severity of adverse effects can be increased when Hexobarbital is combined with Milnacipran.
Naltrexone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Naltrexone.
Bezitramide The risk or severity of adverse effects can be increased when Hexobarbital is combined with Bezitramide.
Morphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Morphine.
Codeine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Codeine.
Hydromorphone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Hydromorphone.
Oxycodone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Oxycodone.
Butorphanol The risk or severity of adverse effects can be increased when Hexobarbital is combined with Butorphanol.
Dextropropoxyphene The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dextropropoxyphene.
Pentazocine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Pentazocine.
Sufentanil The risk or severity of adverse effects can be increased when Hexobarbital is combined with Sufentanil.
Nalbuphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Nalbuphine.
Levorphanol The risk or severity of adverse effects can be increased when Hexobarbital is combined with Levorphanol.
Remifentanil The risk or severity of adverse effects can be increased when Hexobarbital is combined with Remifentanil.
Diphenoxylate The risk or severity of adverse effects can be increased when Hexobarbital is combined with Diphenoxylate.
Oxymorphone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Oxymorphone.
Dezocine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dezocine.
Methadyl acetate The risk or severity of adverse effects can be increased when Hexobarbital is combined with Methadyl acetate.
Dihydroetorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dihydroetorphine.
Diamorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Diamorphine.
Ethylmorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Ethylmorphine.
Etorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Etorphine.
Dextromoramide The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dextromoramide.
Desomorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Desomorphine.
Carfentanil The risk or severity of adverse effects can be increased when Hexobarbital is combined with Carfentanil.
Dihydrocodeine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dihydrocodeine.
Alphacetylmethadol The risk or severity of adverse effects can be increased when Hexobarbital is combined with Alphacetylmethadol.
Dihydromorphine The risk or severity of adverse effects can be increased when Hexobarbital is combined with Dihydromorphine.
Ketobemidone The risk or severity of adverse effects can be increased when Hexobarbital is combined with Ketobemidone.
DPDPE The risk or severity of adverse effects can be increased when Hexobarbital is combined with DPDPE.
Lofentanil The risk or severity of adverse effects can be increased when Hexobarbital is combined with Lofentanil.
Opium The risk or severity of adverse effects can be increased when Hexobarbital is combined with Opium.

Target Protein

Gamma-aminobutyric acid receptor subunit alpha-2 GABRA2
Gamma-aminobutyric acid receptor subunit alpha-3 GABRA3
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4
Gamma-aminobutyric acid receptor subunit alpha-5 GABRA5
Gamma-aminobutyric acid receptor subunit alpha-6 GABRA6
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4
Neuronal acetylcholine receptor subunit alpha-7 CHRNA7
Glutamate receptor 2 GRIA2
Glutamate receptor ionotropic, kainate 2 GRIK2

Referensi & Sumber

Artikel (PubMed)

Contoh Produk & Brand

Produk: 0 • International brands: 4
International Brands
  • Citopan
  • Evipal
  • Evipan
  • Tobinal

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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