Peringatan Keamanan

Symptoms of an overdose typically include sluggishness, incoordination, difficulty in thinking, slowness of speech, faulty judgment, drowsiness or coma, shallow breathing, staggering, and in severe cases coma and death.

Heptabarbital

DB01354

small molecule experimental

Deskripsi

Heptabarbital is an intermediate or short term barbiturate used mainly for sedation and hypnosis.

Struktur Molekul 2D

Berat 250.2936
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

882 Data
Buprenorphine Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Hydrocodone Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Magnesium sulfate The therapeutic efficacy of Heptabarbital can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Heptabarbital may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Mirtazapine Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Orphenadrine Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Pramipexole Heptabarbital may increase the sedative activities of Pramipexole.
Ropinirole Heptabarbital may increase the sedative activities of Ropinirole.
Rotigotine Heptabarbital may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Heptabarbital.
Suvorexant Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Thalidomide Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Heptabarbital.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Heptabarbital.
Sodium oxybate Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Heptabarbital is combined with Botulinum toxin type A.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Heptabarbital is combined with Botulinum toxin type B.
Ethanol Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Heptabarbital may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Heptabarbital.
Fluvoxamine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Heptabarbital is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Heptabarbital is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Heptabarbital is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Heptabarbital is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Heptabarbital is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Heptabarbital is combined with Alaproclate.
Naltrexone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Naltrexone.
Bezitramide The risk or severity of adverse effects can be increased when Heptabarbital is combined with Bezitramide.
Morphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Morphine.
Codeine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Codeine.
Hydromorphone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Hydromorphone.
Meperidine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Meperidine.
Oxycodone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Oxycodone.
Butorphanol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Butorphanol.
Dextropropoxyphene The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dextropropoxyphene.
Pentazocine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Pentazocine.
Sufentanil The risk or severity of adverse effects can be increased when Heptabarbital is combined with Sufentanil.
Alfentanil The risk or severity of adverse effects can be increased when Heptabarbital is combined with Alfentanil.
Fentanyl The risk or severity of adverse effects can be increased when Heptabarbital is combined with Fentanyl.
Nalbuphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Nalbuphine.
Levorphanol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Levorphanol.
Remifentanil The risk or severity of adverse effects can be increased when Heptabarbital is combined with Remifentanil.
Diphenoxylate The risk or severity of adverse effects can be increased when Heptabarbital is combined with Diphenoxylate.
Oxymorphone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Oxymorphone.
Dezocine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dezocine.
Levacetylmethadol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Levacetylmethadol.
Methadyl acetate The risk or severity of adverse effects can be increased when Heptabarbital is combined with Methadyl acetate.
Dihydroetorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dihydroetorphine.
Diamorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Diamorphine.
Ethylmorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Ethylmorphine.
Etorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Etorphine.
Dextromoramide The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dextromoramide.
Desomorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Desomorphine.
Carfentanil The risk or severity of adverse effects can be increased when Heptabarbital is combined with Carfentanil.
Dihydrocodeine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dihydrocodeine.
Alphacetylmethadol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Alphacetylmethadol.
Dihydromorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dihydromorphine.
Ketobemidone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Ketobemidone.
DPDPE The risk or severity of adverse effects can be increased when Heptabarbital is combined with DPDPE.
Lofentanil The risk or severity of adverse effects can be increased when Heptabarbital is combined with Lofentanil.
Opium The risk or severity of adverse effects can be increased when Heptabarbital is combined with Opium.
Normethadone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Normethadone.
Piritramide The risk or severity of adverse effects can be increased when Heptabarbital is combined with Piritramide.
Alphaprodine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Alphaprodine.
Nicomorphine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Nicomorphine.
Meptazinol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Meptazinol.
Phenoperidine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Phenoperidine.
Phenazocine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Phenazocine.
Tilidine The risk or severity of adverse effects can be increased when Heptabarbital is combined with Tilidine.
Carfentanil, C-11 The risk or severity of adverse effects can be increased when Heptabarbital is combined with Carfentanil, C-11.
Benzhydrocodone The risk or severity of adverse effects can be increased when Heptabarbital is combined with Benzhydrocodone.
Naloxegol The risk or severity of adverse effects can be increased when Heptabarbital is combined with Naloxegol.
Mecamylamine The risk or severity of adverse effects can be increased when Mecamylamine is combined with Heptabarbital.
Tropicamide The risk or severity of adverse effects can be increased when Tropicamide is combined with Heptabarbital.
Amantadine The risk or severity of adverse effects can be increased when Amantadine is combined with Heptabarbital.
Cyclopentolate The risk or severity of adverse effects can be increased when Cyclopentolate is combined with Heptabarbital.
Pentolinium The risk or severity of adverse effects can be increased when Pentolinium is combined with Heptabarbital.
Trimethaphan The risk or severity of adverse effects can be increased when Trimethaphan is combined with Heptabarbital.

Target Protein

Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1
Gamma-aminobutyric acid receptor subunit alpha-2 GABRA2
Gamma-aminobutyric acid receptor subunit alpha-3 GABRA3
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4
Gamma-aminobutyric acid receptor subunit alpha-5 GABRA5
Gamma-aminobutyric acid receptor subunit alpha-6 GABRA6
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4
Neuronal acetylcholine receptor subunit alpha-7 CHRNA7
Glutamate receptor 2 GRIA2
Glutamate receptor ionotropic, kainate 2 GRIK2

Referensi & Sumber

Synthesis reference: U.S. Patent 2,501,551.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Medomin — Geigy
  • Medomine — Ciba

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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