A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aripiprazole | The metabolism of Aripiprazole can be increased when combined with Amobarbital. |
| Aripiprazole lauroxil | The metabolism of Aripiprazole lauroxil can be increased when combined with Amobarbital. |
| Buprenorphine | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Hydrocodone | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Magnesium sulfate | The therapeutic efficacy of Amobarbital can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Amobarbital may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Mirtazapine | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Orphenadrine | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Pramipexole | Amobarbital may increase the sedative activities of Pramipexole. |
| Ropinirole | Amobarbital may increase the sedative activities of Ropinirole. |
| Rotigotine | Amobarbital may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Amobarbital. |
| Suvorexant | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Thalidomide | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Secretin porcine | The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Amobarbital. |
| Mefloquine | The therapeutic efficacy of Amobarbital can be decreased when used in combination with Mefloquine. |
| Orlistat | Orlistat can cause a decrease in the absorption of Amobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Acetaminophen | The metabolism of Acetaminophen can be increased when combined with Amobarbital. |
| Propacetamol | The metabolism of Propacetamol can be increased when combined with Amobarbital. |
| Chloramphenicol | The metabolism of Amobarbital can be decreased when combined with Chloramphenicol. |
| Doxycycline | The serum concentration of Doxycycline can be decreased when it is combined with Amobarbital. |
| Felbamate | The serum concentration of Amobarbital can be increased when it is combined with Felbamate. |
| Griseofulvin | The serum concentration of Griseofulvin can be decreased when it is combined with Amobarbital. |
| Lamotrigine | The serum concentration of Lamotrigine can be decreased when it is combined with Amobarbital. |
| Mianserin | The therapeutic efficacy of Amobarbital can be decreased when used in combination with Mianserin. |
| Primidone | The risk or severity of adverse effects can be increased when Primidone is combined with Amobarbital. |
| Methylphenobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Amobarbital. |
| Phenobarbital | The risk or severity of adverse effects can be increased when Phenobarbital is combined with Amobarbital. |
| Pyridoxine | The metabolism of Amobarbital can be increased when combined with Pyridoxine. |
| Teniposide | The serum concentration of Teniposide can be decreased when it is combined with Amobarbital. |
| Ulipristal | The serum concentration of Ulipristal can be decreased when it is combined with Amobarbital. |
| Voriconazole | The serum concentration of Voriconazole can be decreased when it is combined with Amobarbital. |
| Topotecan | Amobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Amobarbital. |
| Sodium oxybate | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Ifosfamide | The metabolism of Ifosfamide can be increased when combined with Amobarbital. |
| Perampanel | The metabolism of Perampanel can be increased when combined with Amobarbital. |
| Warfarin | The metabolism of Warfarin can be increased when combined with Amobarbital. |
| Acenocoumarol | The metabolism of Acenocoumarol can be increased when combined with Amobarbital. |
| (R)-warfarin | The metabolism of (R)-warfarin can be increased when combined with Amobarbital. |
| R,S-Warfarin alcohol | The metabolism of R,S-Warfarin alcohol can be increased when combined with Amobarbital. |
| S,R-Warfarin alcohol | The metabolism of S,R-Warfarin alcohol can be increased when combined with Amobarbital. |
| (S)-Warfarin | The metabolism of (S)-Warfarin can be increased when combined with Amobarbital. |
| Tetracosactide | The risk or severity of liver damage can be increased when Tetracosactide is combined with Amobarbital. |
| Aminophylline | The therapeutic efficacy of Amobarbital can be decreased when used in combination with Aminophylline. |
| Botulinum toxin type A | The risk or severity of adverse effects can be increased when Amobarbital is combined with Botulinum toxin type A. |
| Botulinum toxin type B | The risk or severity of adverse effects can be increased when Amobarbital is combined with Botulinum toxin type B. |
| Meperidine | Amobarbital may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine. |
| Somatostatin | The risk or severity of adverse effects can be increased when Somatostatin is combined with Amobarbital. |
| Ethanol | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Amobarbital may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Amobarbital. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Amobarbital is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Amobarbital is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Amobarbital is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Dapoxetine. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Seproxetine. |
| Indalpine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Amobarbital is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Amobarbital is combined with Alaproclate. |
| Naltrexone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Naltrexone. |
| Bezitramide | The risk or severity of adverse effects can be increased when Amobarbital is combined with Bezitramide. |
| Morphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Morphine. |
| Codeine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Codeine. |
| Hydromorphone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Hydromorphone. |
| Oxycodone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Oxycodone. |
| Butorphanol | The risk or severity of adverse effects can be increased when Amobarbital is combined with Butorphanol. |
| Dextropropoxyphene | The risk or severity of adverse effects can be increased when Amobarbital is combined with Dextropropoxyphene. |
| Pentazocine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Pentazocine. |
| Sufentanil | The risk or severity of adverse effects can be increased when Amobarbital is combined with Sufentanil. |
| Nalbuphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Nalbuphine. |
| Levorphanol | The risk or severity of adverse effects can be increased when Amobarbital is combined with Levorphanol. |
| Remifentanil | The risk or severity of adverse effects can be increased when Amobarbital is combined with Remifentanil. |
| Diphenoxylate | The risk or severity of adverse effects can be increased when Amobarbital is combined with Diphenoxylate. |
| Oxymorphone | The risk or severity of adverse effects can be increased when Amobarbital is combined with Oxymorphone. |
| Dezocine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Dezocine. |
| Methadyl acetate | The risk or severity of adverse effects can be increased when Amobarbital is combined with Methadyl acetate. |
| Dihydroetorphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Dihydroetorphine. |
| Diamorphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Diamorphine. |
| Ethylmorphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Ethylmorphine. |
| Etorphine | The risk or severity of adverse effects can be increased when Amobarbital is combined with Etorphine. |
| Dextromoramide | The risk or severity of adverse effects can be increased when Amobarbital is combined with Dextromoramide. |