Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Spirapril. |
| Amifostine | Spirapril may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Spirapril. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Spirapril. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Spirapril. |
| Obinutuzumab | Spirapril may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Spirapril. |
| Rituximab | Spirapril may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Spirapril. |
| Phentermine | Phentermine may decrease the antihypertensive activities of Spirapril. |
| Midodrine | Midodrine may decrease the antihypertensive activities of Spirapril. |
| Eletriptan | Eletriptan may decrease the antihypertensive activities of Spirapril. |
| Isoetharine | Isoetharine may decrease the antihypertensive activities of Spirapril. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Spirapril. |
| Cabergoline | Cabergoline may decrease the antihypertensive activities of Spirapril. |
| Atomoxetine | Atomoxetine may decrease the antihypertensive activities of Spirapril. |
| Etomidate | Etomidate may decrease the antihypertensive activities of Spirapril. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Spirapril. |
| Dihydroergotamine | Dihydroergotamine may decrease the antihypertensive activities of Spirapril. |
| Amitriptyline | Amitriptyline may decrease the antihypertensive activities of Spirapril. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Spirapril. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Spirapril. |
| Norepinephrine | Norepinephrine may decrease the antihypertensive activities of Spirapril. |
| Mirtazapine | Mirtazapine may decrease the antihypertensive activities of Spirapril. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Spirapril. |
| Phenylpropanolamine | Phenylpropanolamine may decrease the antihypertensive activities of Spirapril. |
| Promazine | Promazine may decrease the antihypertensive activities of Spirapril. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Spirapril. |
| Buspirone | Buspirone may decrease the antihypertensive activities of Spirapril. |
| Nortriptyline | Nortriptyline may decrease the antihypertensive activities of Spirapril. |
| Amoxapine | Amoxapine may decrease the antihypertensive activities of Spirapril. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Spirapril. |
| Atropine | Atropine may decrease the antihypertensive activities of Spirapril. |
| Lisuride | Lisuride may decrease the antihypertensive activities of Spirapril. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Spirapril. |
| Trazodone | Trazodone may decrease the antihypertensive activities of Spirapril. |
| Epinephrine | Epinephrine may decrease the antihypertensive activities of Spirapril. |
| Sumatriptan | Sumatriptan may decrease the antihypertensive activities of Spirapril. |
| Ergotamine | Ergotamine may decrease the antihypertensive activities of Spirapril. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Spirapril. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Spirapril. |
| Trimipramine | Trimipramine may decrease the antihypertensive activities of Spirapril. |
| Risperidone | Risperidone may decrease the antihypertensive activities of Spirapril. |
| Propiomazine | Propiomazine may decrease the antihypertensive activities of Spirapril. |
| Alfentanil | Alfentanil may decrease the antihypertensive activities of Spirapril. |
| Fentanyl | Fentanyl may decrease the antihypertensive activities of Spirapril. |
| Orciprenaline | Orciprenaline may decrease the antihypertensive activities of Spirapril. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Spirapril. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Spirapril. |
| Dobutamine | Dobutamine may decrease the antihypertensive activities of Spirapril. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Spirapril. |
| Benzphetamine | Benzphetamine may decrease the antihypertensive activities of Spirapril. |
| Ritodrine | Ritodrine may decrease the antihypertensive activities of Spirapril. |
| Terbutaline | Terbutaline may decrease the antihypertensive activities of Spirapril. |
| Flupentixol | Flupentixol may decrease the antihypertensive activities of Spirapril. |
| Bitolterol | Bitolterol may decrease the antihypertensive activities of Spirapril. |
| Quinidine | Quinidine may decrease the antihypertensive activities of Spirapril. |
| Almotriptan | Almotriptan may decrease the antihypertensive activities of Spirapril. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Spirapril. |
| Salmeterol | Salmeterol may decrease the antihypertensive activities of Spirapril. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Spirapril. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Spirapril. |
| Formoterol | Formoterol may decrease the antihypertensive activities of Spirapril. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Spirapril. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Spirapril. |
| Albuterol | Salbutamol may decrease the antihypertensive activities of Spirapril. |
| Methoxyflurane | Methoxyflurane may decrease the antihypertensive activities of Spirapril. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Spirapril. |
| Isoprenaline | Isoprenaline may decrease the antihypertensive activities of Spirapril. |
| Arbutamine | Arbutamine may decrease the antihypertensive activities of Spirapril. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Spirapril. |
| Doxepin | Doxepin may decrease the antihypertensive activities of Spirapril. |
| Nefazodone | Nefazodone may decrease the antihypertensive activities of Spirapril. |
| Desipramine | Desipramine may decrease the antihypertensive activities of Spirapril. |
| Pergolide | Pergolide may decrease the antihypertensive activities of Spirapril. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Spirapril. |
| Ergometrine | Ergometrine may decrease the antihypertensive activities of Spirapril. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Spirapril. |
| Paliperidone | Paliperidone may decrease the antihypertensive activities of Spirapril. |
| Arformoterol | Arformoterol may decrease the antihypertensive activities of Spirapril. |
| Fenoterol | Fenoterol may decrease the antihypertensive activities of Spirapril. |
| Pirbuterol | Pirbuterol may decrease the antihypertensive activities of Spirapril. |
| Ephedra sinica root | Ephedra sinica root may decrease the antihypertensive activities of Spirapril. |
| Ephedrine | Ephedrine may decrease the antihypertensive activities of Spirapril. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Spirapril. |
| Procaterol | Procaterol may decrease the antihypertensive activities of Spirapril. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Spirapril. |
| Methotrimeprazine | Methotrimeprazine may decrease the antihypertensive activities of Spirapril. |
| Clenbuterol | Clenbuterol may decrease the antihypertensive activities of Spirapril. |
| Bambuterol | Bambuterol may decrease the antihypertensive activities of Spirapril. |
| MMDA | MMDA may decrease the antihypertensive activities of Spirapril. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Spirapril. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Spirapril. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Spirapril. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Spirapril. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Spirapril. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Spirapril. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Spirapril. |
| Metamfetamine | Metamfetamine may decrease the antihypertensive activities of Spirapril. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Spirapril. |